Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase

Treatment with ETC-1002 alone and in combination with ezetimibe lowers LDL cholesterol in hypercholesterolemic patients with or without statin intolerance

(2016) Paul D. Thompson et al.   Journal of Clinical Lipidology

Residual dyslipidemia according to low-density lipoprotein cholesterol, non–high-density lipoprotein cholesterol, and apolipoprotein B among statin-treated US adults: National Health and Nutrition Examination Survey 2009-2010

(2015) Nathan D. Wong et al.   Journal of Clinical Lipidology

Adenosine triphosphate citrate lyase: Emerging target in the treatment of dyslipidemia

(2015) Hernán N. Lemus et al.   Journal of Clinical Lipidology

Use of ETC-1002 to treat hypercholesterolemia in patients with statin intolerance

(2015) Paul D. Thompson et al.   Journal of Clinical Lipidology

Efficacy and Safety of ETC-1002, a Novel Investigational Low-Density Lipoprotein-Cholesterol–Lowering Therapy for the Treatment of Patients With Hypercholesterolemia and Type 2 Diabetes Mellitus

(2014) Maria J. Gutierrez et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Is High-Intensity Statin Therapy Associated With Lower Statin Adherence Compared With Low- to Moderate-Intensity Statin Therapy? Implications of the 2013 American College of Cardiology/American Heart Association Cholesterol Management Guidelines

(2014) Salim S. Virani et al.   CLINICAL CARDIOLOGY

De novo lipogenesis in health and disease

(2014) Fatima Ameer et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

ETC-1002 regulates immune response, leukocyte homing, and adipose tissue inflammation via LKB1-dependent activation of macrophage AMPK

(2013) Sergey Filippov et al.   JOURNAL OF LIPID RESEARCH

Efficacy and Safety of a Novel Dual Modulator of Adenosine Triphosphate-Citrate Lyase and Adenosine Monophosphate-Activated Protein Kinase in Patients With Hypercholesterolemia

(2013) Christie M. Ballantyne et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Contemporary Management and Attainment of Cholesterol Targets for Patients with Dyslipidemia in China

(2013) Fei Gao et al.   PLoS One

Statin Use and Risk of Diabetes Mellitus in Postmenopausal Women in the Women's Health Initiative

(2012) Annie L. Culver   ARCHIVES OF INTERNAL MEDICINE

AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism

(2012) Stephen L. Pinkosky et al.   JOURNAL OF LIPID RESEARCH

Adverse events associated with individual statin treatments for cardiovascular disease: an indirect comparison meta-analysis

(2011) M. Alberton et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice

(2010) Qiong Wang et al.   JOURNAL OF LIPID RESEARCH