Article
Engineering, Environmental
Bo Situ, Bairong He, Xu Chen, Xiaojing He, Weiwei Feng, Xinyi Ye, Yifang Huang, Xiaolei Xue, Shan Liu, Qiong Xia, Jianjun Zou, Ben Zhong Tang, Lei Zheng
Summary: MASPB is a density-responsive bioprobe for fluorescent sensing of cell nucleus density, capable of distinguishing between tumor cells and normal cells based on nuclear condensation and cellular distribution, providing a rapid tool for nucleus density mapping with potential applications in cancer diagnosis.
CHEMICAL ENGINEERING JOURNAL
(2021)
Review
Chemistry, Analytical
Yanhong Duo, Zhongyuan Xiang, Ge Gao, Guanghong Luo, Ben Zhong Tang
Summary: Fluorescent biosensors have limitations due to the quenching effects of traditional fluorophores, but the discovery of AIEgens has provided opportunities for designing novel turn-on biosensors. Recent developments in AIEgens have shown great potential for molecular design and clinical applications in the field of biomedicine.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Inorganic & Nuclear
Xiaojing Nan, Yuchen Huyan, Hongjuan Li, Shiguo Sun, Yongqian Xu
Summary: Transition metal ions play crucial roles in medicine, life sciences, and environmental science, but some like mercury, copper, and iron ions pose serious health and environmental risks due to biomagnification. Monitoring metal ion levels in organisms and the environment is urgent, and reaction-based fluorescent probes offer higher sensitivity and selectivity than traditional methods. Research on these probes for Hg2+, Cu2+, and Fe2+/Fe2+ detection has advanced in the past decade, with potential for interdisciplinary development in the future.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Chemistry, Multidisciplinary
Hongmin Hao, Chao Xu, Haiyuan Luo, Jinglian Yang, Cong Liu, Bingjia Xu, Guang Shi, Xiaobo Xing, Zhenguo Chi
Summary: A highly emissive photofunctional porous organic polymer film (polyPhTPECz) was constructed using an in situ electropolymerization method. The film showed excellent multifunctional and reusable luminescent sensor abilities for 2,4,6-trinitrophenol (TNP) and Fe3+ in aqueous media, with low detection limits and sensitive detection for TNP vapor. The fluorescence-quenching mechanism for TNP was a combination of electron transfer and resonance energy transfer due to the high fluorescence property and cross-linked porous texture of the polyPhTPECz films.
MATERIALS CHEMISTRY FRONTIERS
(2021)
Article
Biochemistry & Molecular Biology
Dongmi Li, Panpan Lv, Xiao-Wen Han, Zhilei Jia, Min Zheng, Hai-Tao Feng
Summary: A simple tetraphenylethene (TPE) derivative with aggregation-induced emission (AIE) characteristics was synthesized and used as a fluorescent sensor for the detection of nitrophenolic explosives with high selectivity. The sensor could identify nitroaromatic compounds in water solution and solid state, and only hydroxyl-containing nitrophenolic explosives caused fluorescence quenching. The sensing mechanism was investigated using fluorescence titration and H-1 NMR spectra. This AIE-active probe has the potential to be applied in the development of portable explosive detection devices.
Article
Chemistry, Multidisciplinary
Beidou Feng, Kui Wang, Zhe Wang, Huiyu Niu, Ge Wang, Yuehua Chen, Hua Zhang
Summary: A mitochondrial-targeted probe MBI-OMe was developed to specifically detect changes in ferroptosis-induced ClO-. It showed a ratiometric signal in living cells in response to ferroptosis-induced ClO-.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Analytical
Ming Zheng, Qiang Yin, Dongyuan Wang, Zixuan Zhao, Qinghua Hu, Hongqing Wang
Summary: A novel triphenylamine-based fluorescent sensor (USC-001) has been designed and prepared for the detection of uranyl ions in acidic and high water ratio environments, showing good selectivity and potential applications. The sensor has been successfully utilized for the detection of uranyl ions in actual water samples and biological cells.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Wenjie Liang, Gang Nie, Jinjin Che, Zhengjiang Zhang, Dugang Chen, Wenbo Wu
Summary: There is a lack of effective and friendly diagnostic technique for alcoholic liver disease (ALD). Fluorescence imaging, which has been widely applied in disease diagnostic ascribed to the merits of high sensitivity, excellent temporal resolution and minimal invasiveness, is probably a good candidate for ALD studying.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Engineering, Electrical & Electronic
Tonglei Cheng, Wei Liu, Dianchang Song, Zhiyuan Yin, Fan Zhang, Bin Li, Xuenan Zhang, Takenobu Suzuki, Yasutake Ohishi, Fang Wang
Summary: This paper proposes a compact fluorescent probe based on the fluorescence intensity ratio (FIR) technique for real-time thermal monitoring of chips. The sensing unit uses a self-made tellurite optical fiber (TOF) co-doped with Er3+/Yb3+ ions. The temperature information is demodulated by analyzing the up-conversion fluorescence emission spectra generated using a 980 nm laser pump. The probe shows fast response and small error in real-time thermal monitoring of the CPU. It provides a novel and reliable method for chip temperature monitoring.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2022)
Article
Chemistry, Analytical
Dimitrios A. Diamantis, Adamantia Agalou, Maria Chatziathanasiadou, Georgios S. Markopoulos, Sofia Bellou, Zoi Kanaki, Timothy Crook, Nelofer Syed, Theodoros Rampias, Apostolos Klinakis, Evangelos Kolettas, Dimitris Beis, Andreas G. Tzakos
Summary: Biotin-Yellow, a tumor-targeting fluorescent and colorimetric probe, shows unprecedented turn-on near-infrared fluorescence properties and can effectively recognize and discriminate cancer cells. It is also capable of real-time bioimaging tracking of upregulated biothiol activity in cancer cells, as validated in zebrafish and mice xenografts.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Dingyuan Yan, Miao Wang, Qian Wu, Niu Niu, Meng Li, Ruixiang Song, Jie Rao, Miaomiao Kang, Zhijun Zhang, Feifan Zhou, Dong Wang, Ben Zhong Tang
Summary: A versatile theranostic agent, TPA-BT-DPTQ, was designed and prepared for simultaneous fluorescence imaging, photoacoustic imaging, photothermal imaging, and thermal eradication of tumors. The photothermal therapy mediated by TPA-BT-DPTQ nanoparticles not only destroys the primary tumor but also enhances immunogenicity for further suppressing the growth of distant tumors. Combining photothermal therapy with a PD-L1 antibody prevents cancer metastasis and recurrence.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Spectroscopy
Pai Liu, Yu-ling Liu, He Huang, Guang Bai, Yong-jin Peng
Summary: The level of hydrogen sulfide (H2S) in the human body is associated with various diseases. Therefore, the detection of H2S level in biological systems is important and has attracted attention from researchers. This study thoroughly investigated the mechanisms of a highly efficient fluorescent probe based on the Fluorescence Resonance Energy Transfer (FRET), providing insights for designing new probes applicable in biological systems.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Shouxin Zhang, Bo Yang, Bo Yuan, Chuan Zhou, Min Zhang, Yue Zhao, Pingwei Ye, Li Li, Heguo Li
Summary: A probe (PQSP) based on quinoxalinone unit and styrene pyridine group was developed for visually detecting a sarin simulant diethyl chlorophosphate (DCP) with excellent sensing properties. The probe showed an intramolecular charge-transfer process and had a fast response time and high sensitivity for detecting DCP vapor.
Article
Engineering, Environmental
Farid Ahmed, Weiqing Xu, Muhammad Muzammal Hussain, Waheed Ullah Khan, Hai Xiong
Summary: In this study, a novel fluorescent probe using silver-mediated red emissive carbon dots (RCDs@Ag+) was developed to distinguish cancer cells from normal cells through the bioimaging of glutathione (GSH). The probe showed high selectivity and fluorescence intensity changes upon GSH detection. The method can be used to identify cancer cells overexpressing GSH.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Wei Wang, Min Ji, Junqing Chen, Peng Wang
Summary: In this study, a turn-on type aggregation-induced emission (AIE) fluorescent probe BQM-NBD was developed for selective detection of Cys and Hcy in organisms, showing good selectivity. Additionally, BQM-NBD exhibited low cytotoxicity when used for imaging Cys in living cells.
Article
Chemistry, Multidisciplinary
Jiameng Li, Hang Xu, Zian Zhang, Yafeng Hao, Hanjie Wang, Xian Huang
ADVANCED FUNCTIONAL MATERIALS
(2020)
Article
Biochemical Research Methods
Minye Yang, Meihui Cui, Weixun Wang, Yaodong Yang, Jin Chang, Jianye Hao, Hanjie Wang
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2020)
Article
Engineering, Environmental
Yingying Zhang, Hongbin Chen, Hanjie Wang, Tiange Wang, Huizhuo Pan, Wanying Ji, Jin Chang
CHEMICAL ENGINEERING JOURNAL
(2020)
Article
Oncology
Congcong Wang, Ruiguo Zhang, Jian Tan, Zhaowei Meng, Yueqian Zhang, Ning Li, Hanjie Wang, Jin Chang, Renfei Wang
Article
Biotechnology & Applied Microbiology
Tao Sun, Yingying Zhang, Chaonan Zhang, Hanjie Wang, Huizhuo Pan, Jing Liu, Zhixiang Li, Lei Chen, Jin Chang, Weiwen Zhang
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2020)
Article
Chemistry, Multidisciplinary
Wei Ling, Jingxian Yu, Ning Ma, Ya Li, Ziyue Wu, Rong Liang, Yafeng Hao, Huizhuo Pan, Wentao Liu, Bo Fu, Kun Wang, Hanjie Wang, Lizhu Li, Xing Sheng, Hui Peng, Baoan Ning, Jiajia Yang, Xian Huang
ADVANCED FUNCTIONAL MATERIALS
(2020)
Article
Engineering, Environmental
Guohui Cheng, Hanjie Wang, Chaonan Zhang, Yafeng Hao, Tiange Wang, Yingying Zhang, Yu Tian, Jin Chang
CHEMICAL ENGINEERING JOURNAL
(2020)
Article
Chemistry, Multidisciplinary
Yingying Zhang, Xin Zhang, Hanjie Wang, Yu Tian, Huizhuo Pan, Lili Zhang, Feng Wang, Jin Chang
Summary: A magneto-luminescence microdevice (MLMD) was developed in this study to achieve optical emission through non-contact excitation using a rotating magnetic field, allowing for remote stimulation of biological tissues. This innovative approach has the potential to inspire new applications in biomedicine.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Engineering, Environmental
Tiandi He, HanJie Wang, Tiange Wang, GaoJu Pang, YingYing Zhang, Chaonan Zhang, Peng Yu, Jin Chang
Summary: The study presents a novel approach using a sonogenetic nanosystem for cancer immunotherapy, which activates mechanosensitive ion channels to induce cell apoptosis for precise cancer treatment. This system shows potential for expanding the application of sonogenetics in cancer therapy.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Jingxian Yu, Wei Ling, Ya Li, Ning Ma, Ziyue Wu, Rong Liang, Huizhuo Pan, Wentao Liu, Bo Fu, Kun Wang, Chenxi Li, Hanjie Wang, Hui Peng, Baoan Ning, Jiajia Yang, Xian Huang
Summary: The integration of optical fibers and flexible electronics allows for more sophisticated applications in biomedicine and biology. A multi-channel flexible device has been demonstrated in vivo with rats for optical stimulation and simultaneous monitoring of spontaneous/evoked signals using microelectrode arrays. The device's biocompatibility has been characterized, showing potential for long-term animal studies.
Review
Nanoscience & Nanotechnology
Jun Kang, Ayesha Tahir, Hanjie Wang, Jin Chang
Summary: Viruses, highly infectious pathogens, cause significant global fatalities. Nanotechnology shows promise in virus detection and tracking, but faces challenges such as clinical false positives, limitations of QDs, and the need for improved real-time tracking.
WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY
(2021)
Article
Engineering, Electrical & Electronic
Shi Zaifeng, Ye Peng, Sun Cheng, Luo Tao, Wang Hanjie, Pan Huizhuo
LASER & OPTOELECTRONICS PROGRESS
(2020)
Correction
Materials Science, Biomaterials
Han Yang, Hong-sheng Liu, Wen Hou, Jun-xiao Gao, Yue Duan, Daohe Wei, Xiao-qun Gong, Han-jie Wang, Xiao-li Wu, Jin Chang
JOURNAL OF MATERIALS CHEMISTRY B
(2020)
Article
Materials Science, Biomaterials
Hanjie Wang, Chaonan Zhang, Yingying Zhang, Ran Tian, Guohui Cheng, Huizhuo Pan, Meihui Cui, Jin Chang
JOURNAL OF MATERIALS CHEMISTRY B
(2020)
Article
Materials Science, Biomaterials
Han Yang, Hong-sheng Liu, Wen Hou, Jun-xiao Gao, Yue Duan, Daohe Wei, Xiao-qun Gong, Han-jie Wang, Xiao-li Wu, Jin Chang
JOURNAL OF MATERIALS CHEMISTRY B
(2020)