A pathogenic and clonally expanded B cell transcriptome in active multiple sclerosis

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

(2020) David Schafflick et al.   Nature Communications

Association of intrathecal pleocytosis and IgG synthesis with axonal damage in early MS

(2020) Sinah Engel et al.   Neurology-Neuroimmunology & Neuroinflammation

Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation

(2020) Ekaterina Esaulova et al.   Neurology-Neuroimmunology & Neuroinflammation

Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

(2019) Dvir Aran et al.   NATURE IMMUNOLOGY

High frequency of shared clonotypes in human B cell receptor repertoires

(2019) Cinque Soto et al.   NATURE

Silent Progression in Disease Activity-Free Relapsing Multiple Sclerosis

(2019) et al.   ANNALS OF NEUROLOGY

Induction of brain‐infiltrating T‐bet‐expressing B cells in multiple sclerosis

(2019) Jamie Langelaar et al.   ANNALS OF NEUROLOGY

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

(2019) Christopher S. McGinnis et al.   Cell Systems

Metagenomic next-generation sequencing of samples from pediatric febrile illness in Tororo, Uganda

(2019) Akshaya Ramesh et al.   PLoS One

Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens

(2019) Senjuti Saha et al.   mBio

B-cell Therapy for Multiple Sclerosis: Entering an era

(2018) Ariele L. Greenfield et al.   ANNALS OF NEUROLOGY

The prevalence of hyperkalemia in the United States

(2018) Keith A. Betts et al.   CURRENT MEDICAL RESEARCH AND OPINION

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

(2018) Alan J Thompson et al.   LANCET NEUROLOGY

Detection and removal of barcode swapping in single-cell RNA-seq data

(2018) Jonathan A. Griffiths et al.   Nature Communications

A general and flexible method for signal extraction from single-cell RNA-seq data

(2018) Davide Risso et al.   Nature Communications

Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing

(2018) Michael R. Wilson et al.   JAMA Neurology

Optimized Threshold Inference for Partitioning of Clones From High-Throughput B Cell Repertoire Sequencing Data

(2018) Nima Nouri et al.   Frontiers in Immunology

Dimensionality reduction for visualizing single-cell data using UMAP

(2018) Etienne Becht et al.   NATURE BIOTECHNOLOGY

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

(2017) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis

(2017) Xavier Montalban et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives

(2017) Alessandra Tammaro et al.   PHARMACOLOGY & THERAPEUTICS

Long-term evolution of multiple sclerosis disability in the treatment era

(2016) et al.   ANNALS OF NEUROLOGY

GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis

(2016) J P Hussman et al.   GENES AND IMMUNITY

Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity

(2016) Matthew A. Care et al.   JOURNAL OF IMMUNOLOGY

No evidence for an effect on brain atrophy rate of atorvastatin add-on to interferon β1b therapy in relapsing–remitting multiple sclerosis (the ARIANNA study)

(2016) Roberta Lanzillo et al.   Multiple Sclerosis Journal

gEVE: a genome-based endogenous viral element database provides comprehensive viral protein-coding sequences in mammalian genomes

(2016) So Nakagawa et al.   Database-The Journal of Biological Databases and Curation

Immune cell-specific transcriptional profiling highlights distinct molecular pathways controlled by Tob1 upon experimental autoimmune encephalomyelitis

(2016) Alessandro Didonna et al.   Scientific Reports

No evidence for an effect on brain atrophy rate of atorvastatin add-on to interferon β1b therapy in relapsing–remitting multiple sclerosis (the ARIANNA study)

(2016) Roberta Lanzillo et al.   Multiple Sclerosis Journal

The BLUEPRINT Data Analysis Portal

(2016) José María Fernández et al.   Cell Systems

DiagnosingBalamuthia mandrillarisEncephalitis With Metagenomic Deep Sequencing

(2015) Michael R. Wilson et al.   ANNALS OF NEUROLOGY

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data: Table 1.

(2015) Namita T. Gupta et al.   BIOINFORMATICS

Emerging role of IL-16 in cytokine-mediated regulation of multiple sclerosis

(2015) Dusanka S. Skundric et al.   CYTOKINE

MiXCR: software for comprehensive adaptive immunity profiling

(2015) Dmitriy A Bolotin et al.   NATURE METHODS

ENCODE data at the ENCODE portal

(2015) Cricket A. Sloan et al.   NUCLEIC ACIDS RESEARCH

Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli

(2015) William J. Housley et al.   Science Translational Medicine

pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires

(2014) Jason A. Vander Heiden et al.   BIOINFORMATICS

Intrathecal somatic hypermutation of IgM in multiple sclerosis and neuroinflammation

(2014) Eduardo Beltrán et al.   BRAIN

Effect of high-dose simvastatin on brain atrophy and disability in secondary progressive multiple sclerosis (MS-STAT): a randomised, placebo-controlled, phase 2 trial

(2014) Jeremy Chataway et al.   LANCET

Transcriptomic Meta-Analysis of Multiple Sclerosis and Its Experimental Models

(2014) Barbara B. R. Raddatz et al.   PLoS One

Immunoglobulin class-switched B cells form an active immune axis between CNS and periphery in multiple sclerosis

(2014) A. Palanichamy et al.   Science Translational Medicine

B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

(2014) J. N. H. Stern et al.   Science Translational Medicine

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls

(2013) Dorothee Nickles et al.   HUMAN MOLECULAR GENETICS

Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity

(2013) Ulf Schulze-Topphoff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Gene expression analysis of relapsing–remitting, primary progressive and secondary progressive multiple sclerosis

(2013) R Ratzer et al.   Multiple Sclerosis Journal

PRICE: Software for the Targeted Assembly of Components of (Meta) Genomic Sequence Data

(2013) J. Graham Ruby et al.   G3-Genes Genomes Genetics

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Atorvastatin added to interferon beta for relapsing multiple sclerosis: a randomized controlled trial

(2012) Christian Philipp Kamm et al.   JOURNAL OF NEUROLOGY

Randomized controlled trial of atorvastatin in clinically isolated syndrome: The STAyCIS study

(2012) E. Waubant et al.   NEUROLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

An RNA Profile Identifies Two Subsets of Multiple Sclerosis Patients Differing in Disease Activity

(2012) L. Ottoboni et al.   Science Translational Medicine

Epstein-Barr virus in the multiple sclerosis brain: a controversial issue--report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria

(2011) H. Lassmann et al.   BRAIN

More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases

(2011) Niannian Ji et al.   Immunotherapy

Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse

(2011) Ana Longhini et al.   Journal of Neuroinflammation

Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial

(2011) Ludwig Kappos et al.   LANCET

Simvastatin as add-on therapy to interferon beta-1a for relapsing-remitting multiple sclerosis (SIMCOMBIN study): a placebo-controlled randomised phase 4 trial

(2011) Per Soelberg Sorensen et al.   LANCET NEUROLOGY

Identification of IgG subclasses' oligoclonal bands in multiple sclerosis CSF

(2010) J. Losy et al.   ACTA NEUROLOGICA SCANDINAVICA

Primary infection with the epstein-barr virus and risk of multiple sclerosis

(2010) Lynn I. Levin et al.   ANNALS OF NEUROLOGY

Detection of Epstein–Barr virus and B-cell follicles in the multiple sclerosis brain: what you find depends on how and where you look

(2010) Francesca Aloisi et al.   BRAIN

Central memory CD4+ T cells dominate the normal cerebrospinal fluid

(2010) Marieke T. de Graaf et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Gene expression profiling in multiple sclerosis brain

(2010) Ranjan Dutta et al.   NEUROBIOLOGY OF DISEASE

Absence of Epstein-Barr virus in the brain and CSF of patients with multiple sclerosis

(2010) S. A. Sargsyan et al.   NEUROLOGY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain

(2009) Simon N. Willis et al.   BRAIN

Refined characterization and reference values of the pediatric T- and B-cell compartments

(2009) R. van Gent et al.   CLINICAL IMMUNOLOGY

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis

(2008) Birgit Obermeier et al.   NATURE MEDICINE

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event

(2008) J.-C. Corvol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phenotypic and functional heterogeneity of human memory B cells

(2008) Iñaki Sanz et al.   SEMINARS IN IMMUNOLOGY