Highly Active Anti-Diabetic Metal-Organic Framework

We have synthesized a novel zinc metal organic framework (MOP) under mild hydrothermal routes using 5-aminotetrazole and methyl-2-amino-4-isonicotinate anionic ligands. The MOF exhibits a three-dimensional structure with intense blue-greenish photoluminescence emission at room temperature in the solid state. The luminescence, porosity, and adsorption capacity for CO2 and H-2 of the Zn-based MOF have been fully determined using a combination of computational methods and experimental techniques. The synthesized Zn-based compound in this study exhibited a remarkable in vivo anti-diabetic activity and low in vitro cell toxicity.