Review
Infectious Diseases
Luis E. Escobar, Scott Carver, Paul C. Cross, Luca Rossi, Emily S. Almberg, Michael J. Yabsley, Kevin D. Niedringhaus, Peach Van Wick, Ernesto Dominguez-Villegas, Francis Gakuya, Yue Xie, Samer Angelone, Christian Gortazar, Francisca Astorga
Summary: Sarcoptic mange, caused by the mite Sarcoptes scabiei, is an emerging disease threatening the welfare and conservation of wildlife. The disease has a global distribution and affects a wide range of host species. Recent research shows increasing transmission and virulence of sarcoptic mange in wildlife populations.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Parasitology
Vicky Wilkinson, Kotaro Tokano, David Nichols, Alynn Martin, Roz Holme, David Phalen, Kate Mounsey, Michael Charleston, Alexandre Kreiss, Ruth Pye, Elizabeth Browne, Christina Naesborg-Nielsen, Shane A. Richards, Scott Carver
Summary: The study found that Fluralaner is a safe and effective treatment for sarcoptic mange in bare-nosed wombats, with a single dose lasting over 1-3 months. It has economic and treatment-effort-related advantages over moxidectin, the most commonly used alternative. The recommended dose for adult bare-nosed wombats is 25 mg/kg of Fluralaner formulated as Bravecto Spot-On for Large Dogs.
PARASITES & VECTORS
(2021)
Article
Veterinary Sciences
Mirabela O. Dumitrache, Marie-Christine Cadiergues
Summary: This paper reviews the evidence comparing different types of systemic treatment for canine scabies. The analysis of the results shows that afoxolaner, fluralaner, sarolaner, as well as several macrocyclic lactones such as selamectin, moxidectin, and milbemycin oxime, can lead to parasitological and clinical cure.
BMC VETERINARY RESEARCH
(2023)
Article
Parasitology
Shanker K. Singh, Amit K. Jaiswal, Sanju Kumari, Ruchi Singh Gaur, Prabha Sharma, Richa Khushboo, Manu Jaiswal
Summary: This study evaluated the therapeutic efficacy of oral fluralaner in pet rabbits with severe sarcoptic mange. The results showed significant improvement in skin lesions after a single oral dose, but complete clearance of the mites was not achieved. Complete clinical recovery was observed in all rabbits after 30 days of treatment. Further research is needed to comprehensively assess the safety and efficacy of this drug in rabbits with different severities of mange.
VETERINARY PARASITOLOGY
(2022)
Article
Veterinary Sciences
Georgiana Deak, Barbara Moroni, Ana Maria Boncea, Luisa Rambozzi, Luca Rossi, Andrei Daniel Mihalca
Summary: This paper presents two clinical scenarios of sarcoptic mange in camelids, successfully treated with a combination of ectocides and subcutaneous moxidectin. The treatment resulted in negative scrapings and regrowth of hair in previously affected areas for both cases.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Federica Obber, Roberto Celva, Martina Libanora, Graziana Da Rold, Debora Dellamaria, Piergiovanni Partel, Enrico Ferraro, Maria Santa Calabrese, Lia Morpurgo, Simone Roberto Rolando Pisano, Carlo Vittorio Citterio, Rudi Cassini
Summary: This study analyzed 15 years (2006-2020) of passive surveillance and demographic data to describe a mange outbreak in the Alpine chamois population in the Dolomites. An enhanced passive surveillance protocol was implemented to evaluate its efficiency compared to the ordinary protocol in identifying dead chamois and determining the cause of death. The results confirmed the role of mange in chamois mortality and emphasized the need to consider other factors affecting population dynamics. The enhanced protocol improved carcass retrieval and cause of death identification, but its long-term and wide-scale application may be costly. Future passive surveillance should incorporate other strategies to study the eco-epidemiology of the disease in wild Caprinae.
Article
Parasitology
Christopher Charles Evans, Dorothy Normile, Sheryl Gamble, Frank Guerino, Michael T. T. Dzimianski, Andrew Riddell Moorhead
Summary: This study investigates the effects of oral medication Fluralaner (Bravecto) on the major vector of canine heartworm, Aedes aegypti mosquitoes. The results show that mosquitoes fed with blood from dogs treated with Fluralaner experience a significant reduction in survival and reproductive ability, supporting the potential for reducing heartworm transmission by directly killing the vector and indirectly reducing the local vector population.
PARASITES & VECTORS
(2023)
Article
Veterinary Sciences
Dario d'Ovidio, Domenico Santoro
Summary: Sarcoptes scabiei are cutaneous mites that parasitize mammals, with specific genetic variants associated with different animal species. Sarcoptes scabiei var. cuniculi causes sarcoptic mange in rabbits, characterized by intense itching, hair loss, redness, scales, and crusts. Treatment of this condition typically involves avermectins and multiple administrations.
TOPICS IN COMPANION ANIMAL MEDICINE
(2021)
Article
Parasitology
Bernadete Dantas Queiroga Tamyres, Cardoso Pereira Gomez Luanderson, Eduardo Rodrigues de Sena, Wilo Victor dos Santos, Rafael Pontes Ferreira Henrique, Vicente Toscano de Araujo-Neto, Andressa Noronha Barbosa-Silva, Carlos Ramon do Nascimento Brito, Romeika Karla dos Reis Lima, Joao Ciro Fagundes-Neto, Lucia Maria da Cunha Galvao, Henrique Rocha de Medeiros, Antonia Claudia Jacome da Camara, Manuela Sales Lima Nascimento, Renata Antonaci Gama, Paulo Marcos Matta Guedes
Summary: The study evaluated the insecticidal effect of fluralaner on Triatoma brasiliensis after feeding on treated dogs, showing 100% mortality within 7 months post-treatment, declining to 0% after 12 months. This indicates a potential long-term approach to control vector transmission of Chagas disease, especially in endemic areas.
PARASITES & VECTORS
(2021)
Article
Agriculture, Dairy & Animal Science
Fernando Najera, Elena Crespo, Amalia Garcia-Talens, Rebeca Grande-Gomez, Francisco Javier Herrera-Sanchez, Michaela Gentil, Carmen Cortes-Garcia, Elisabeth Mueller, Rafael Calero-Bernal, Luis Revuelta
Summary: The study describes the diagnosis of Sarcoptes scabiei in a dead European wildcat in Spain, marking the first description of this mite in a European wildcat. Considering the critical demography of European wildcats in the southernmost population of the Iberian Peninsula, the potential impacts of infectious diseases, including sarcoptic mange, should be taken into account in disease surveillance programs for this species.
Article
Parasitology
Christina Naesborg-Nielsen, Raphael Eisenhofer, Tamieka A. Fraser, Vicky Wilkinson, Christopher P. Burridge, Scott Carver
Summary: This study investigated the microbial changes associated with sarcoptic mange in a marsupial host, as well as the fungal microbial changes on the skin of hosts suffering from sarcoptic mange. The results showed significant changes in microbial communities and diversity in mange-affected individuals, with an increased abundance of potential pathogenic microbial taxa. The findings suggest that the impacts of mange on the epidermal microbiota may be generalizable across host species.
PARASITES & VECTORS
(2022)
Article
Parasitology
Csilla Becskei, Julian Liebenberg, Tiago Fernandes, Stasia Borowski, Lina D'Hanis, Sean P. Mahabir
Summary: Two-monthly doses of Simparica Trio (R) reduced S. scabiei mite counts by 99.2% and eliminated S. scabiei mites in 100% of dogs, confirming the high effectiveness of Simparica Trio (R) in treating sarcoptic mange in dogs caused by S. scabiei var. canis.
PARASITES & VECTORS
(2023)
Article
Parasitology
Melissa Petersen, Riaan Maree, Alta Viljoen, Julian E. E. Liebenberg, Frank Guerino
Summary: In two 90-day studies, it was found that a single administration of fluralaner chewable tablets at the minimum recommended dose rate of 25 mg/kg was 100% effective in eliminating H.longicornis ticks from dogs. This efficacy was maintained for 90 days following treatment.
PARASITES & VECTORS
(2023)
Article
Parasitology
Barbara Moroni, Samer Angelone, Jesus M. Perez, Anna Rita Molinar Min, Mario Pasquetti, Paolo Tizzani, Jorge Ramon Lopez-Olvera, Marta Valldeperes, Jose Enrique Granados, Santiago Lavin, Gregorio Mentaberre, Leonor Camacho-Sillero, Carlos Martinez-Carrasco, Alvaro Oleaga, Monica Candela, Pier Giuseppe Meneguz, Luca Rossi
Summary: The study in Spain reveals the existence of three genetic strains of Sarcoptes scabiei in wild ruminant populations, with two clusters being host- and geography-related, and one cluster consisting of multi-host mites from geographically distant populations. This suggests that the spread and persistence of the parasite may be influenced by host species composition and the permissiveness of each host population to different strains, among other factors. Investigating wildlife-livestock interactions and human-driven introductions or trades of wild and domestic animals is crucial to prevent further spread of sarcoptic mange in unaffected natural areas of the Iberian Peninsula.
PARASITES & VECTORS
(2021)
Article
Microbiology
Flavia Fiori, Rogerio Cunha de Paula, Pedro Enrique Navas-Suarez, Ricardo Luiz Pires Boulhosa, Ricardo Augusto Dias
Summary: The maned wolf is the largest South American canid and is considered an endangered species in Brazil due to habitat loss, hunting, and other threats. Sarcoptic mange, caused by the mite Sarcoptes scabiei, is an emerging disease affecting wildlife, including maned wolves. A study in Brazil identified 52 cases of sarcoptic mange in maned wolves, indicating a rapid and widespread spread of the disease in the species' range.