Phillyrin Mitigates Apoptosis and Oxidative Stress in Hydrogen Peroxide-Treated RPE Cells through Activation of the Nrf2 Signaling Pathway

A novel Bcl-2 inhibitor, BM-1197, induces apoptosis in malignant lymphoma cells through the endogenous apoptotic pathway

(2020) Yue-Li Sun et al.   BMC CANCER

Stanniocalcin-1 Alleviates Contrast-Induced Acute Kidney Injury by Regulating Mitochondrial Quality Control via the Nrf2 Pathway

(2020) Fei Zhao et al.   Oxidative Medicine and Cellular Longevity

Forsythiaside prevents β-amyloid-induced hippocampal slice injury by upregulating 2-arachidonoylglycerol via cannabinoid receptor 1-dependent NF-κB pathway

(2019) Liqing Chen et al.   NEUROCHEMISTRY INTERNATIONAL

New strategy of bone marrow mesenchymal stem cells against oxidative stress injury via Nrf2 pathway: oxidative stress preconditioning

(2019) Fei Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Phillyrin Relieves Lipopolysaccharide-Induced AKI by Protecting Against Glycocalyx Damage and Inhibiting Inflammatory Responses

(2019) Dong Zhang et al.   INFLAMMATION

Elusive drusen and changing terminology of AMD

(2018) P. T. V. M. De Jong   EYE

Hepatoprotective effect of Forsythiae Fructus water extract against carbon tetrachloride-induced liver fibrosis in mice

(2018) Yi Zhang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Genetics of age-related macular degeneration (AMD)

(2017) Margaret M. DeAngelis et al.   HUMAN MOLECULAR GENETICS

New insights into the effects and mechanism of a classic traditional Chinese medicinal formula on influenza prevention

(2017) Huan Chen et al.   PHYTOMEDICINE

Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration

(2017) Nady Golestaneh et al.   Cell Death & Disease

Protective responses to sublytic complement in the retinal pigment epithelium

(2016) Li Xuan Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

5-Hydroxy-7-Methoxyflavone Triggers Mitochondrial-Associated Cell Death via Reactive Oxygen Species Signaling in Human Colon Carcinoma Cells

(2016) Monika Bhardwaj et al.   PLoS One

RPE necroptosis in response to oxidative stress and in AMD

(2015) Jakub Hanus et al.   AGEING RESEARCH REVIEWS

Prohibitin as the Molecular Binding Switch in the Retinal Pigment Epithelium

(2015) Srinivas R. Sripathi et al.   PROTEIN JOURNAL

Protective Effects of Phillyrin on H2O2-induced Oxidative Stress and Apoptosis in PC12 Cells

(2014) Teng Wei et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Forsythin inhibits lipopolysaccharide-induced inflammation by suppressing JAK-STAT and p38 MAPK signalings and ROS production

(2014) Xiaolong Pan et al.   INFLAMMATION RESEARCH

γ-Rays-generated ROS induce apoptosis via mitochondrial and cell cycle alteration in smooth muscle cells

(2014) Sandra Claro et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Use of JC-1 to assess mitochondrial membrane potential in sea urchin sperm

(2014) M.T. Binet et al.   JOURNAL OF EXPERIMENTAL MARINE BIOLOGY AND ECOLOGY

Mechanisms of age-related macular degeneration and therapeutic opportunities

(2013) Menno van Lookeren Campagne et al.   JOURNAL OF PATHOLOGY

The estimated prevalence and incidence of late stage age related macular degeneration in the UK

(2012) Christopher G Owen et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Associations of Cigarette Smoking But Not Serum Fatty Acids with Age-related Macular Degeneration in a Japanese Population

(2011) Sho Kabasawa et al.   OPHTHALMOLOGY

The A Allele of the -576G>A Polymorphism of the Transferrin Gene Is Associated with the Increased Risk of Age-Related Macular Degeneration in Smokers

(2011) Daniel Wysokinski et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

(2010) Noriyuki Matsuda et al.   JOURNAL OF CELL BIOLOGY

Redox-dependent signaling system Nrf2/ARE in inflammation

(2010) E. B. Menshikova et al.   MOLECULAR BIOLOGY

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications

(2009) Jin-Qiang Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Many Roles of FAS Receptor Signaling in the Immune System

(2009) Andreas Strasser et al.   IMMUNITY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Antioxidants and Free Radical Scavengers for the Treatment Of Stroke, Traumatic Brain Injury and Aging

(2008) J. Weber et al.   CURRENT MEDICINAL CHEMISTRY

ROS and p53: A versatile partnership

(2008) Bin Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Epigallocatechin-3-gallate augments antioxidant activities and inhibits inflammation during bleomycin-induced experimental pulmonary fibrosis through Nrf2–Keap1 signaling

(2008) Narayanan Sriram et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS