Histone 3 lysine-27 demethylase KDM6A coordinates with KMT2B to play an oncogenic role in NSCLC by regulating H3K4me3

UTX Mutations in Human Cancer

(2019) Lu Wang et al.   CANCER CELL

The histone H3 lysine-27 demethylase UTX plays a critical role in colorectal cancer cell proliferation

(2019) Xin Tang et al.   Cancer Cell International

Emerging therapies for non-small cell lung cancer

(2019) Chao Zhang et al.   Journal of Hematology & Oncology

WNT Signaling in Disease

(2019) Ng et al.   Cells

The Prognostic Significance of Histone Demethylase UTX in Esophageal Squamous Cell Carcinoma

(2018) Shau-Hsuan Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma

(2018) Xiaoxi Li et al.   Nature Communications

Lung Cancer Therapy Targeting Histone Methylation: Opportunities and Challenges

(2018) Yuchen Chen et al.   Computational and Structural Biotechnology Journal

Epigenetics in cancer stem cells

(2017) Tan Boon Toh et al.   Molecular Cancer

UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition

(2017) Teresa Ezponda et al.   Cell Reports

MYC Deregulation in Primary Human Cancers

(2017) Manpreet Kalkat et al.   Genes

Epigenetic Therapeutics: A New Weapon in the War Against Cancer

(2016) Nita Ahuja et al.   Annual Review of Medicine

Histone Modifications and Cancer

(2016) James E. Audia et al.   Cold Spring Harbor Perspectives in Biology

cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions

(2015) Linchong Sun et al.   CELL RESEARCH

Targeting EZH2 and PRC2 dependence as novel anticancer therapy

(2015) Bowen Xu et al.   EXPERIMENTAL HEMATOLOGY

Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival

(2015) L Fan et al.   ONCOGENE

The roles of chromatin-remodelers and epigenetic modifiers in kidney cancer

(2015) Lili Liao et al.   Cancer Genetics

Non-small-cell lung cancer

(2015) Cesare Gridelli et al.   Nature Reviews Disease Primers

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

(2014) Joni Van der Meulen et al.   BLOOD

UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells

(2014) Jae-Hwan Kim et al.   CANCER RESEARCH

The H3K27me3 demethylase UTX in normal development and disease

(2014) Joni Van der Meulen et al.   Epigenetics

MYC on the Path to Cancer

(2012) Chi V. Dang   CELL

Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4

(2012) H.-M. Herz et al.   GENES & DEVELOPMENT

The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming

(2012) Abed AlFatah Mansour et al.   NATURE

UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity

(2012) C. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development

(2012) Karl B. Shpargel et al.   PLoS Genetics

Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A

(2011) A. M. Jankowska et al.   BLOOD

Epigenetic diet: impact on the epigenome and cancer

(2011) Tabitha M Hardy et al.   Epigenomics

An operational definition of epigenetics

(2009) S. L. Berger et al.   GENES & DEVELOPMENT

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

(2009) Gijs van Haaften et al.   NATURE GENETICS

Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma

(2009) G Akiri et al.   ONCOGENE