Dietary Methionine Restriction Signals to the Brain Through Fibroblast Growth Factor 21 to Regulate Energy Balance and Remodeling of Adipose Tissue

The Components of Age-Dependent Effects of Dietary Methionine Restriction on Energy Balance in Rats

(2018) Desiree Wanders et al.   Obesity

Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice

(2018) Sho Matsui et al.   Nature Communications

Concentration-dependent linkage of dietary methionine restriction to the components of its metabolic phenotype

(2017) Laura A. Forney et al.   Obesity

An integrative analysis of tissue-specific transcriptomic and metabolomic responses to short-term dietary methionine restriction in mice

(2017) Sujoy Ghosh et al.   PLoS One

Role of GCN2-Independent Signaling Through a Noncanonical PERK/NRF2 Pathway in the Physiological Responses to Dietary Methionine Restriction

(2016) Desiree Wanders et al.   DIABETES

Pharmacologic Effects of FGF21 Are Independent of the “Browning” of White Adipose Tissue

(2015) Murielle M. Véniant et al.   Cell Metabolism

Central Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice

(2015) Nicholas Douris et al.   ENDOCRINOLOGY

UCP1 is an essential mediator of the effects of methionine restriction on energy balance but not insulin sensitivity

(2015) Desiree Wanders et al.   FASEB JOURNAL

Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction

(2015) Yuvraj N. Patil et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Compromised responses to dietary methionine restriction in adipose tissue but not liver ofob/obmice

(2015) Kirsten P. Stone et al.   Obesity

Discrete Aspects of FGF21 In Vivo Pharmacology Do Not Require UCP1

(2015) Ricardo J. Samms et al.   Cell Reports

Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21

(2014) Emma K. Lees et al.   AGING CELL

FGF21 Acts Centrally to Induce Sympathetic Nerve Activity, Energy Expenditure, and Weight Loss

(2014) Bryn M. Owen et al.   Cell Metabolism

Mechanisms of Increased In Vivo Insulin Sensitivity by Dietary Methionine Restriction in Mice

(2014) Kirsten P. Stone et al.   DIABETES

FGF21 Maintains Glucose Homeostasis by Mediating the Cross Talk Between Liver and Brain During Prolonged Fasting

(2014) Q. Liang et al.   DIABETES

A systems biology analysis of the unique and overlapping transcriptional responses to caloric restriction and dietary methionine restriction in rats

(2014) Sujoy Ghosh et al.   FASEB JOURNAL

Interplay between FGF21 and insulin action in the liver regulates metabolism

(2014) Brice Emanuelli et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional impact of dietary methionine restriction on systemic inflammation: Relevance to biomarkers of metabolic disease during aging

(2013) Desiree Wanders et al.   BIOFACTORS

Adiponectin Mediates the Metabolic Effects of FGF21 on Glucose Homeostasis and Insulin Sensitivity in Mice

(2013) Zhuofeng Lin et al.   Cell Metabolism

An FGF21-Adiponectin-Ceramide Axis Controls Energy Expenditure and Insulin Action in Mice

(2013) William L. Holland et al.   Cell Metabolism

Remodeling the Integration of Lipid Metabolism Between Liver and Adipose Tissue by Dietary Methionine Restriction in Rats

(2013) B. E. Hasek et al.   DIABETES

Pegylated Fgf21 rapidly normalizes insulin-stimulated glucose utilization in diet-induced insulin resistant mice

(2013) Raul C. Camacho et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

FGF21 contributes to neuroendocrine control of female reproduction

(2013) Bryn M Owen et al.   NATURE MEDICINE

FGF21 regulates metabolism and circadian behavior by acting on the nervous system

(2013) Angie L Bookout et al.   NATURE MEDICINE

Circulating Fibroblast Growth Factors as Metabolic Regulators—A Critical Appraisal

(2012) Bo Angelin et al.   Cell Metabolism

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

(2012) Xunshan Ding et al.   Cell Metabolism

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Genomic and Metabolic Responses to Methionine-Restricted and Methionine-Restricted, Cysteine-Supplemented Diets in Fischer 344 Rat Inguinal Adipose Tissue, Liver and Quadriceps Muscle

(2012) Carmen E. Perrone et al.   Journal of Nutrigenetics and Nutrigenomics

Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo

(2012) Andrew C. Adams et al.   PLoS One

Methionine-Restricted C57BL/6J Mice Are Resistant to Diet-Induced Obesity and Insulin Resistance but Have Low Bone Density

(2012) Gene P. Ables et al.   PLoS One

The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

(2012) Andrew C. Adams et al.   Molecular Metabolism

Dietary methionine restriction enhances metabolic flexibility and increases uncoupled respiration in both fed and fasted states

(2010) Barbara E. Hasek et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Role of β-adrenergic receptors in the hyperphagic and hypermetabolic responses to dietary methionine restriction

(2010) Eric P. Plaisance et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Methionine restriction effects on mitochondrial biogenesis and aerobic capacity in white adipose tissue, liver, and skeletal muscle of F344 rats

(2010) Carmen E. Perrone et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects

(2009) Jing Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY