BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers

Selective recognition of c-MYC Pu22 G-quadruplex by a fluorescent probe

(2019) Qianqian Zhai et al.   NUCLEIC ACIDS RESEARCH

Recent Progress of Targeted G-Quadruplex-Preferred Ligands Toward Cancer Therapy

(2019) Sefan Asamitsu et al.   MOLECULES

Lighting up the Native Viral RNA Genome with a Fluorogenic Probe for the Live-Cell Visualization of Virus Infection

(2019) Xingyu Luo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hybrid-type and two-tetrad antiparallel telomere DNA G-quadruplex structures in living human cells

(2019) Hong-Liang Bao et al.   NUCLEIC ACIDS RESEARCH

Extreme mechanical diversity of human telomeric DNA revealed by fluorescence-force spectroscopy

(2019) Jaba Mitra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New substituted quinoxalines inhibit triple-negative breast cancer by specifically downregulating the c-MYC transcription

(2019) Ming-Hao Hu et al.   NUCLEIC ACIDS RESEARCH

Molecular Recognition of the Hybrid-2 Human Telomeric G-Quadruplex by Epiberberine: Insights into Conversion of Telomeric G-Quadruplex Structures

(2018) Clement Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures

(2018) C. Saintomé et al.   CHEMICAL COMMUNICATIONS

Structural Dynamics of Lateral and Diagonal Loops of Human Telomeric G-Quadruplexes in Extended MD Simulations

(2018) Barira Islam et al.   Journal of Chemical Theory and Computation

Solution structures of multiple G-quadruplex complexes induced by a platinum(II)-based tripod reveal dynamic binding

(2018) Wenting Liu et al.   Nature Communications

Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids

(2018) Dexter C. Davis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of human telomere G-quadruplex in the presence of a model drug along the thermal unfolding pathway

(2018) Federico Bianchi et al.   NUCLEIC ACIDS RESEARCH

Adaptive and Specific Recognition of Telomeric G-Quadruplexes via Polyvalency Induced Unstacking of Binding Units

(2017) Jibin Abraham Punnoose et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PRL-3 promotes telomere deprotection and chromosomal instability

(2017) Shenyi Lian et al.   NUCLEIC ACIDS RESEARCH

Chiral metallohelices enantioselectively target hybrid human telomeric G-quadruplex DNA

(2017) Andong Zhao et al.   NUCLEIC ACIDS RESEARCH

Involvement of G-triplex and G-hairpin in the multi-pathway folding of human telomeric G-quadruplex

(2017) Xi-Miao Hou et al.   NUCLEIC ACIDS RESEARCH

Specifically targeting mixed-type dimeric G-quadruplexes using berberine dimers

(2017) Zi-Qi Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

(2017) D. Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Unraveling the Thermodynamics of the Folding and Interconversion of Human Telomere G-Quadruplexes

(2016) Matjaž Bončina et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds

(2016) Jutta Zimmer et al.   MOLECULAR CELL

Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole

(2016) Ming-Hao Hu et al.   NUCLEIC ACIDS RESEARCH

A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes

(2016) Zi-Fu Wang et al.   NUCLEIC ACIDS RESEARCH

Highly selective, sensitive and fluorescent sensing of dimeric G-quadruplexes by a dimeric berberine

(2016) Chun-Qiong Zhou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Small molecule regulated dynamic structural changes of human G-quadruplexes

(2016) Manish Debnath et al.   Chemical Science

Nuclear-Receptor-Mediated Telomere Insertion Leads to Genome Instability in ALT Cancers

(2015) Paulina Marzec et al.   CELL

Tetraphenylethene Derivatives with Different Numbers of Positively Charged Side Arms have Different Multimeric G-Quadruplex Recognition Specificity

(2015) Qi Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

Small-molecule quadruplex-targeted drug discovery

(2014) Stephan A. Ohnmacht et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dynamics and stability of polymorphic human telomeric G-quadruplex under tension

(2014) Huijuan You et al.   NUCLEIC ACIDS RESEARCH

Two cationic porphyrin isomers showing different multimeric G-quadruplex recognition specificity against monomeric G-quadruplexes

(2014) Xiao-Xi Huang et al.   NUCLEIC ACIDS RESEARCH

Targeting Human Telomeric Higher-Order DNA: Dimeric G-Quadruplex Units Serve as Preferred Binding Site

(2013) Chuanqi Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of the Interaction between Long Telomeric DNA and Macrocyclic Hexaoxazole (6OTD) Dimer of a G-quadruplex Ligand

(2013) Keisuke Iida et al.   MOLECULES

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Specific recognition and stabilization of monomeric and multimeric G-quadruplexes by cationic porphyrin TMPipEOPP under molecular crowding conditions

(2013) Li-Na Zhu et al.   NUCLEIC ACIDS RESEARCH

Structure and Stability of Higher-Order Human Telomeric Quadruplexes

(2011) Luigi Petraccone et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Telomeric repeat-containing RNA structure in living cells

(2010) Y. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Consecutive Formation of G-Quadruplexes in Human Telomeric-Overhang DNA: A Protective Capping Structure for Telomere Ends

(2009) Yan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Small-Molecule Selectively Recognizes Human Telomeric G-Quadruplex DNA and Regulates Its Conformational Switch

(2009) Mingli Chen et al.   BIOPHYSICAL JOURNAL

Small Angle X-ray Scattering Analysis of Deoxyguanosine 5′-Monophosphate Self-Assembing in Solution: Nucleation and Growth of G-Quadruplexes

(2009) Paolo Mariani et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

A Reducing and Oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes

(2008) Jan Vogelsang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single molecule conformational analysis of DNA G-quadruplexes

(2008) Pravin S. Shirude et al.   BIOCHIMIE

Molecular Dynamics and Principal Components Analysis of Human Telomeric Quadruplex Multimers

(2008) Shozeb Haider et al.   BIOPHYSICAL JOURNAL

Stability and kinetics of G-quadruplex structures

(2008) A. N. Lane et al.   NUCLEIC ACIDS RESEARCH