Conformational flexibility and oligomerization of BRCA2 regions induced by RAD51 interaction

DSS1 and ssDNA regulate oligomerization of BRCA2

(2020) Hang Phuong Le et al.   NUCLEIC ACIDS RESEARCH

Temperature Dependence of Intrinsically Disordered Proteins in Simulations: What are We Missing?

(2019) S. Jephthah et al.   Journal of Chemical Theory and Computation

Expanding the Paradigm: Intrinsically Disordered Proteins and Allosteric Regulation

(2018) Rebecca B. Berlow et al.   JOURNAL OF MOLECULAR BIOLOGY

Architectural plasticity of human BRCA2–RAD51 complexes in DNA break repair

(2017) Humberto Sánchez et al.   NUCLEIC ACIDS RESEARCH

Distinct binding of BRCA2 BRC repeats to RAD51 generates differential DNA damage sensitivity

(2016) Gouri Chatterjee et al.   NUCLEIC ACIDS RESEARCH

BRCA2 regulates DMC1-mediated recombination through the BRC repeats

(2016) Juan S. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SFMetrics: an analysis tool for scanning force microscopy images of biomolecules

(2015) Humberto Sánchez et al.   BMC BIOINFORMATICS

An Integrated in Silico Approach to Analyze the Involvement of Single Amino Acid Polymorphisms in FANCD1/BRCA2-PALB2 and FANCD1/BRCA2-RAD51 Complex

(2014) C. George Priya Doss et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Classification of Intrinsically Disordered Regions and Proteins

(2014) Robin van der Lee et al.   CHEMICAL REVIEWS

Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor

(2014) Taha Shahid et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Temperature-dependent solvation modulates the dimensions of disordered proteins

(2014) R. Wuttke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multisteric Regulation by Structural Disorder in Modular Signaling Proteins: An Extension of the Concept of Allostery

(2013) Peter Tompa   CHEMICAL REVIEWS

Combined optical and topographic imaging reveals different arrangements of human RAD54 with presynaptic and postsynaptic RAD51-DNA filaments

(2013) H. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Versatility from Protein Disorder

(2012) M. M. Babu et al.   SCIENCE

Intrinsically disordered proteins from A to Z

(2011) Vladimir N. Uversky   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Unraveling the mechanism of BRCA2 in homologous recombination

(2011) William K Holloman   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms

(2011) A. Carreira et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purified human BRCA2 stimulates RAD51-mediated recombination

(2010) Ryan B. Jensen et al.   NATURE

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA

(2010) Jie Liu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA

(2010) Tina Thorslund et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Temperature-dependent structural changes in intrinsically disordered proteins: Formation of α-helices or loss of polyproline II?

(2010) Magnus Kjaergaard et al.   PROTEIN SCIENCE

The Carboxyl Terminus of Brca2 Links the Disassembly of Rad51 Complexes to Mitotic Entry

(2009) Nabieh Ayoub et al.   CURRENT BIOLOGY

Structural basis for recruitment of BRCA2 by PALB2

(2009) Antony W Oliver et al.   EMBO REPORTS

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase

(2009) Eeson Rajendra et al.   NUCLEIC ACIDS RESEARCH