Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy

Virus-Mimicking Cell Capture Using Heterovalency Magnetic DNA Nanoclaws

(2019) Zhiru Wang et al.   ACS Applied Materials & Interfaces

Systematic review of targeted extracellular vesicles for drug delivery – Considerations on methodological and biological heterogeneity

(2019) Johann Mar Gudbergsson et al.   JOURNAL OF CONTROLLED RELEASE

Methotrexate-Loaded Extracellular Vesicles Functionalized with Therapeutic and Targeted Peptides for the Treatment of Glioblastoma Multiforme

(2018) Zhilan Ye et al.   ACS Applied Materials & Interfaces

Modification of Extracellular Vesicles by Fusion with Liposomes for the Design of Personalized Biogenic Drug Delivery Systems

(2018) Max Piffoux et al.   ACS Nano

Valency-Controlled Framework Nucleic Acid Signal Amplifiers

(2018) Qi Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing

(2018) Romain Rouet et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Anti-HER2 scFv-Directed Extracellular Vesicle-Mediated mRNA-Based Gene Delivery Inhibits Growth of HER2-Positive Human Breast Tumor Xenografts by Prodrug Activation

(2018) Jing-Hung Wang et al.   MOLECULAR CANCER THERAPEUTICS

Manufacturing Exosomes: A Promising Therapeutic Platform

(2018) Ivano Luigi Colao et al.   TRENDS IN MOLECULAR MEDICINE

DNA Nanostructures at the Interface with Biology

(2018) Katherine E. Bujold et al.   Chem

Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

(2018) Krijn K. Dijkstra et al.   CELL

Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles

(2018) Yamin Li et al.   Biomaterials Science

Tumor Cell-Derived Extracellular Vesicle-Coated Nanocarriers: An Efficient Theranostic Platform for the Cancer-Specific Delivery of Anti-miR-21 and Imaging Agents

(2018) Rajendran JC Bose et al.   ACS Nano

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Multistage Delivery Nanoparticle Facilitates Efficient CRISPR/dCas9 Activation and Tumor Growth Suppression In Vivo

(2018) Qi Liu et al.   Advanced Science

Delivery strategies of the CRISPR-Cas9 gene-editing system for therapeutic applications

(2017) Chang Liu et al.   JOURNAL OF CONTROLLED RELEASE

Functional Delivery of Lipid-Conjugated siRNA by Extracellular Vesicles

(2017) Aisling J. O’Loughlin et al.   MOLECULAR THERAPY

Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression

(2017) Fengmei Pi et al.   Nature Nanotechnology

Multiple-Armed Tetrahedral DNA Nanostructures for Tumor-Targeting, Dual-Modality in Vivo Imaging

(2016) Dawei Jiang et al.   ACS Applied Materials & Interfaces

Advances in therapeutic CRISPR/Cas9 genome editing

(2016) Nataša Savić et al.   Translational Research

Recurrent AAV2-related insertional mutagenesis in human hepatocellular carcinomas

(2015) Jean-Charles Nault et al.   NATURE GENETICS

Aptamers and Their Applications in Nanomedicine

(2015) Hongguang Sun et al.   Small

Programmable Engineering of a Biosensing Interface with Tetrahedral DNA Nanostructures for Ultrasensitive DNA Detection

(2014) Meihua Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

(2014) Dong Gao et al.   CELL

Exploration of liver cancer genomes

(2014) Tatsuhiro Shibata et al.   Nature Reviews Gastroenterology & Hepatology

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Functional DNA Nanostructures for Theranostic Applications

(2013) Hao Pei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Smart Drug Delivery Nanocarriers with Self-Assembled DNA Nanostructures

(2013) Jiang Li et al.   ADVANCED MATERIALS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Mesenchymal Stem Cells Secrete Immunologically Active Exosomes

(2013) Bin Zhang et al.   STEM CELLS AND DEVELOPMENT

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

(2012) Shin-ichiro Ohno et al.   MOLECULAR THERAPY

Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma

(2011) Junfang Ji et al.   Cell and Bioscience

Lipid Membranes Carrying Lipophilic Cholesterol-Based Oligonucleotides—Characterization and Application on Layer-by-Layer Coated Particles

(2009) Andreas Bunge et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells

(2008) Dihua Shangguan et al.   ANALYTICAL CHEMISTRY

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells

(2008) Khalid Al-Nedawi et al.   NATURE CELL BIOLOGY