Inflammasome Caspase-1 Activity is Elevated in Cerebrospinal Fluid After Aneurysmal Subarachnoid Hemorrhage and Predicts Functional Outcome

Elevated Cerebrospinal Fluid Protein Is Associated with Unfavorable Functional Outcome in Spontaneous Subarachnoid Hemorrhage

(2020) Neil A. Nadkarni et al.   Journal of Stroke & Cerebrovascular Diseases

MPO is partially associated with neutrophil deleterious effect in acute cerebral ischemia

(2020) Ilaria Maestrini et al.   NEUROLOGY

Matrix Metalloproteinases in Acute Intracerebral Hemorrhage

(2020) Simona Lattanzi et al.   Neurotherapeutics

Heme-Derived Metabolic Signals Dictate Immune Responses

(2020) Giacomo Canesin et al.   Frontiers in Immunology

Levels of caspase-1 in cerebrospinal fluid of patients with traumatic brain injury: correlation with intracranial pressure and outcome

(2020) Jon Pérez-Bárcena et al.   JOURNAL OF NEUROSURGERY

Programmed Cell Deaths and Potential Crosstalk With Blood–Brain Barrier Dysfunction After Hemorrhagic Stroke

(2020) Yuanjian Fang et al.   Frontiers in Cellular Neuroscience

Meningeal lymphatics clear erythrocytes that arise from subarachnoid hemorrhage

(2020) Jinman Chen et al.   Nature Communications

Severe cognitive impairment in aneurysmal subarachnoid hemorrhage: Predictors and relationship to functional outcome

(2020) Joseph R. Geraghty et al.   Journal of Stroke & Cerebrovascular Diseases

Inflammasome proteins as biomarkers of traumatic brain injury

(2019) Nadine Kerr et al.   PLoS One

Neuroinflammation and Microvascular Dysfunction After Experimental Subarachnoid Hemorrhage: Emerging Components of Early Brain Injury Related to Outcome

(2019) Joseph R. Geraghty et al.   Neurocritical Care

The role of TLR4 and HO‐1 in neuroinflammation after subarachnoid hemorrhage

(2019) Yosuke Akamatsu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Role of Vesicle Trafficking and Release in Oligodendrocyte Biology

(2019) Cory R. Reiter et al.   NEUROCHEMICAL RESEARCH

Pharmacological Inhibitors of the NLRP3 Inflammasome

(2019) Ayesha Zahid et al.   Frontiers in Immunology

Role of Damage Associated Molecular Pattern Molecules (DAMPs) in Aneurysmal Subarachnoid Hemorrhage (aSAH)

(2018) Shafqat Chaudhry et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis

(2018) Brienne A. McKenzie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroinflammation as a Target for Intervention in Subarachnoid Hemorrhage

(2018) Airton Leonardo de Oliveira Manoel et al.   Frontiers in Neurology

Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer’s disease mouse model

(2018) Joseph Flores et al.   Nature Communications

Proposal of a grading system for predicting discharge mortality and functional outcome in patients with aneurysmal subarachnoid hemorrhage

(2018) Georgios A. Maragkos et al.   World Neurosurgery

Monomeric C-Reactive Protein and Cerebral Hemorrhage: From Bench to Bedside

(2018) Mario Di Napoli et al.   Frontiers in Immunology

Gasdermin Family: a Promising Therapeutic Target for Stroke

(2018) Sheng Chen et al.   Translational Stroke Research

Subarachnoid hemorrhage – Induced block of cerebrospinal fluid flow: Role of brain coagulation factor III (tissue factor)

(2017) Eugene V Golanov et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A bioluminescent caspase-1 activity assay rapidly monitors inflammasome activation in cells

(2017) Martha O'Brien et al.   JOURNAL OF IMMUNOLOGICAL METHODS

TLR4 signal ablation attenuated neurological deficits by regulating microglial M1/M2 phenotype after traumatic brain injury in mice

(2017) Xiaolong Yao et al.   JOURNAL OF NEUROIMMUNOLOGY

Subarachnoid Hemorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate

(2017) Romain Goulay et al.   STROKE

Neutrophil-to-lymphocyte ratio and neurological deterioration following acute cerebral hemorrhage

(2017) Simona Lattanzi et al.   Oncotarget

Aneurysmal Subarachnoid Hemorrhage and Neuroinflammation: A Comprehensive Review

(2016) Brandon Lucke-Wold et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Paravascular pathways contribute to vasculitis and neuroinflammation after subarachnoid hemorrhage independently of glymphatic control

(2016) C Luo et al.   Cell Death & Disease

Inflammasome Proteins in Cerebrospinal Fluid of Patients with Subarachnoid Hemorrhage are Biomarkers of Early Brain Injury and Functional Outcome

(2016) Qi Wu et al.   World Neurosurgery

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis

(2015) Roni Nowarski et al.   CELL

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

Mechanisms of unconventional secretion of IL-1 family cytokines

(2015) Mercedes Monteleone et al.   CYTOKINE

The pathogenic role of the inflammasome in neurodegenerative diseases

(2015) Leslie C. Freeman et al.   JOURNAL OF NEUROCHEMISTRY

Exosome-mediated inflammasome signaling after central nervous system injury

(2015) Juan Pablo de Rivero Vaccari et al.   JOURNAL OF NEUROCHEMISTRY

Biomarkers as outcome predictors in subarachnoid hemorrhage – a systematic review

(2014) Caron M. Hong et al.   BIOMARKERS

Activation and Regulation of Cellular Inflammasomes: Gaps in Our Knowledge for Central Nervous System Injury

(2014) Juan Pablo de Rivero Vaccari et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Treating inflammation by blocking interleukin-1 in humans

(2013) Charles A. Dinarello et al.   SEMINARS IN IMMUNOLOGY

The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure

(2012) Thomas Maslanik et al.   BRAIN BEHAVIOR AND IMMUNITY

Progress report on new antiepileptic drugs: A summary of the Eleventh Eilat Conference (EILAT XI)

(2012) Meir Bialer et al.   EPILEPSY RESEARCH

Inflammasome proteins in cerebrospinal fluid of brain-injured patients as biomarkers of functional outcome

(2012) Stephanie Adamczak et al.   JOURNAL OF NEUROSURGERY

Clinical Prediction Models for Aneurysmal Subarachnoid Hemorrhage: A Systematic Review

(2012) Blessing N. R. Jaja et al.   Neurocritical Care

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Which Clinical Variable Influences Health-Related Quality of Life the Most After Spontaneous Subarachnoid Hemorrhage? Hunt and Hess Scale, Fisher Score, World Federation of Neurosurgeons Score, Brussels Coma Score, and Glasgow Coma Score Compared

(2012) Thomas Kapapa et al.   World Neurosurgery

Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2)

(2011) R Loch Macdonald et al.   LANCET NEUROLOGY

Inflammasome and IL-1β-Mediated Disorders

(2010) Hal M. Hoffman et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Cellular Microparticles as a Marker for Cerebral Vasospasm in Spontaneous Subarachnoid Hemorrhage

(2010) Peter Lackner et al.   STROKE

Definition of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage as an Outcome Event in Clinical Trials and Observational Studies

(2010) Mervyn D.I. Vergouwen et al.   STROKE

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Effects of Glasgow Outcome Scale Misclassification on Traumatic Brain Injury Clinical Trials

(2008) Juan Lu et al.   JOURNAL OF NEUROTRAUMA

Subarachnoid Hemorrhage: Is It Time for a New Direction?

(2008) J. Cahill et al.   STROKE