Lung cancer LDCT screening and mortality reduction — evidence, pitfalls and future perspectives

Mapping the spectrum of psychological and behavioural responses to low‐dose CT lung cancer screening offered within a Lung Health Check

(2020) Sonja Kummer et al.   HEALTH EXPECTATIONS

Mortality Reduction with Low-Dose CT Screening for Lung Cancer

(2020) Stephen W. Duffy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial

(2020) Harry J. de Koning et al.   NEW ENGLAND JOURNAL OF MEDICINE

External validation of a convolutional neural network artificial intelligence tool to predict malignancy in pulmonary nodules

(2020) David R Baldwin et al.   THORAX

Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

(2020) Linda Kachuri et al.   Nature Communications

Baseline Results of the West London lung cancer screening pilot study – Impact of mobile scanners and dual risk model utilisation

(2020) Emily C. Bartlett et al.   LUNG CANCER

Patient and carer perceived barriers to early presentation and diagnosis of lung cancer: a systematic review

(2019) Shemana Cassim et al.   BMC CANCER

Development of Protocol for Korean Lung Cancer Screening Project (K-LUCAS) to Evaluate Effectiveness and Feasibility to Implement National Cancer Screening Program

(2019) Jaeho Lee et al.   Cancer Research and Treatment

Feasibility of lung cancer prediction from low-dose CT scan and smoking factors using causal models

(2019) Vineet K Raghu et al.   THORAX

Comparing and contrasting predictive biomarkers for immunotherapy and targeted therapy of NSCLC

(2019) D. Ross Camidge et al.   Nature Reviews Clinical Oncology

Prolonged lung cancer screening reduced 10-year mortality in the MILD trial: new confirmation of lung cancer screening efficacy

(2019) U Pastorino et al.   ANNALS OF ONCOLOGY

Evaluation of a health service adopting proactive approach to reduce high risk of lung cancer: the Liverpool Healthy Lung Programme

(2019) Bhagabati Ghimire et al.   LUNG CANCER

End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography

(2019) Diego Ardila et al.   NATURE MEDICINE

Artificial intelligence and radiomics in pulmonary nodule management: current status and future applications

(2019) S. Ather et al.   CLINICAL RADIOLOGY

Lung cancer mortality reduction by LDCT screening – results from the randomised German LUSI trial

(2019) Nikolaus Becker et al.   INTERNATIONAL JOURNAL OF CANCER

Sex and survival in non-small cell lung cancer: A nationwide cohort study

(2019) Cecilia Radkiewicz et al.   PLoS One

Probability of cancer in lung nodules using sequential volumetric screening up to 12 months: the UKLS trial

(2019) Michael W Marcus et al.   THORAX

Lung cancer screening registry reveals low-dose CT screening remains heavily underutilized

(2019) Danh Pham et al.   Clinical Lung Cancer

Ten-year results of the Multicentric Italian Lung Detection trial demonstrate the safety and efficacy of biennial lung cancer screening

(2019) U. Pastorino et al.   EUROPEAN JOURNAL OF CANCER

A comparative modeling analysis of risk-based lung cancer screening strategies

(2019) Kevin ten Haaf et al.   JNCI-Journal of the National Cancer Institute

Cost-Effectiveness Analysis of Lung Cancer Screening in the United States

(2019) Steven D. Criss et al.   ANNALS OF INTERNAL MEDICINE

Risk-Targeted Lung Cancer Screening

(2018) Vaibhav Kumar et al.   ANNALS OF INTERNAL MEDICINE

Cancer incidence and mortality in China, 2014

(2018) Wanqing Chen et al.   Chinese Journal of Cancer Research

Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer

(2018) Yanhong Liu et al.   Journal of Thoracic Oncology

New Subsolid Pulmonary Nodules in Lung Cancer Screening: The NELSON Trial

(2018) Joan E. Walter et al.   Journal of Thoracic Oncology

Cost-effectiveness of low-dose CT screening for lung cancer in a European country with high prevalence of smoking—A modelling study

(2018) Yuki Tomonaga et al.   LUNG CANCER

Relationship between the number of new nodules and lung cancer probability in incidence screening rounds of CT lung cancer screening: The NELSON study

(2018) Joan E. Walter et al.   LUNG CANCER

Lung cancer risk to personalise annual and biennial follow-up computed tomography screening

(2018) Anton Schreuder et al.   THORAX

Implementing lung cancer screening: baseline results from a community-based ‘Lung Health Check’ pilot in deprived areas of Manchester

(2018) Phil A Crosbie et al.   THORAX

Risk Assessment and Risk Minimization in Nanomedicine: A Need for Predictive, Alternative, and 3Rs Strategies

(2018) Lisa Accomasso et al.   Frontiers in Pharmacology

Pulmonary nodules measurements in CT lung cancer screening

(2018) Marjolein A. Heuvelmans et al.   Journal of Thoracic Disease

Changing cancer survival in China during 2003–15: a pooled analysis of 17 population-based cancer registries

(2018) Hongmei Zeng et al.   Lancet Global Health

Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins

(2018) et al.   JAMA Oncology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Projections in Breast and Lung Cancer Mortality among Women: A Bayesian Analysis of 52 Countries Worldwide

(2018) Juan Carlos Martín-Sánchez et al.   CANCER RESEARCH

Sex-Dependent Staging in Non–Small-Cell Lung Cancer; Analysis of the Effect of Sex Differences in the Eighth Edition of the Tumor, Node, Metastases Staging System

(2018) Zoe Wainer et al.   Clinical Lung Cancer

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

(2018) Xuemei Ji et al.   Nature Communications

Lung Cancer Screening with Low-Dose CT: Baseline Screening Results in Shanghai

(2018) Li Fan et al.   ACADEMIC RADIOLOGY

Low-dose computed tomography for lung cancer screening in high-risk populations: a systematic review and economic evaluation

(2018) Tristan Snowsill et al.   HEALTH TECHNOLOGY ASSESSMENT

An Update on the European Lung Cancer Screening Trials and Comparison of Lung Cancer Screening Recommendations in Europe

(2018) Daiwei Han et al.   JOURNAL OF THORACIC IMAGING

The cost-effectiveness of the Manchester ‘lung health checks’, a community-based lung cancer low-dose CT screening pilot

(2018) Sebastian Hinde et al.   LUNG CANCER

Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges

(2018) Luis M. Seijo et al.   Journal of Thoracic Oncology

Predicting Malignancy Risk of Screen-Detected Lung Nodules–Mean Diameter or Volume

(2018) Martin Tammemagi et al.   Journal of Thoracic Oncology

The Cost-Effectiveness of High-Risk Lung Cancer Screening and Drivers of Program Efficiency

(2017) Sonya Cressman et al.   Journal of Thoracic Oncology

European position statement on lung cancer screening

(2017) Matthijs Oudkerk et al.   LANCET ONCOLOGY

Participant selection for lung cancer screening by risk modelling (the Pan-Canadian Early Detection of Lung Cancer [PanCan] study): a single-arm, prospective study

(2017) Martin C Tammemagi et al.   LANCET ONCOLOGY

Relationship between nodule count and lung cancer probability in baseline CT lung cancer screening: The NELSON study

(2017) Marjolein A Heuvelmans et al.   LUNG CANCER

Recommendations for Measuring Pulmonary Nodules at CT: A Statement from the Fleischner Society

(2017) Alexander A. Bankier et al.   RADIOLOGY

Guidelines for Management of Incidental Pulmonary Nodules Detected on CT Images: From the Fleischner Society 2017

(2017) Heber MacMahon et al.   RADIOLOGY

Mortality, survival and incidence rates in the ITALUNG randomised lung cancer screening trial

(2017) Eugenio Paci et al.   THORAX

Impact of low-dose CT screening on smoking cessation among high-risk participants in the UK Lung Cancer Screening Trial

(2017) Kate Brain et al.   THORAX

Should Nonsmokers Be Excluded from Early Lung Cancer Screening with Low-Dose Spiral Computed Tomography? Community-Based Practice in Shanghai

(2017) Xiaoyang Luo et al.   Translational Oncology

Performance and Cost-Effectiveness of Computed Tomography Lung Cancer Screening Scenarios in a Population-Based Setting: A Microsimulation Modeling Analysis in Ontario, Canada

(2017) Kevin ten Haaf et al.   PLOS MEDICINE

Risk prediction models for selection of lung cancer screening candidates: A retrospective validation study

(2017) Kevin ten Haaf et al.   PLOS MEDICINE

Influence of lung nodule margin on volume- and diameter-based reader variability in CT lung cancer screening

(2017) Daiwei Han et al.   BRITISH JOURNAL OF RADIOLOGY

Towards automatic pulmonary nodule management in lung cancer screening with deep learning

(2017) Francesco Ciompi et al.   Scientific Reports

CT Screening for Lung Cancer: Part-Solid Nodules in Baseline and Annual Repeat Rounds

(2016) Claudia I. Henschke et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

Maximum-Intensity-Projection and Computer-Aided-Detection Algorithms as Stand-Alone Reader Devices in Lung Cancer Screening Using Different Dose Levels and Reconstruction Kernels

(2016) Lukas Ebner et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer

(2016) John K Field et al.   HEALTH TECHNOLOGY ASSESSMENT

Development and Validation of Risk Models to Select Ever-Smokers for CT Lung Cancer Screening

(2016) Hormuzd A. Katki et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Natural History of Pulmonary Subsolid Nodules: A Prospective Multicenter Study

(2016) Ryutaro Kakinuma et al.   Journal of Thoracic Oncology

The IASLC Lung Cancer Staging Project: Proposals for Revision of the TNM Stage Groupings in the Forthcoming (Eighth) Edition of the TNM Classification for Lung Cancer

(2016) Peter Goldstraw et al.   Journal of Thoracic Oncology

Lung cancer incidence and mortality in National Lung Screening Trial participants who underwent low-dose CT prevalence screening: a retrospective cohort analysis of a randomised, multicentre, diagnostic screening trial

(2016) Edward F Patz et al.   LANCET ONCOLOGY

Occurrence and lung cancer probability of new solid nodules at incidence screening with low-dose CT: analysis of data from the randomised, controlled NELSON trial

(2016) Joan E Walter et al.   LANCET ONCOLOGY

Biennial lung cancer screening in Canada with smoking cessation—outcomes and cost-effectiveness

(2016) John R. Goffin et al.   LUNG CANCER

Lung Cancer Deaths in the National Lung Screening Trial Attributed to Nonsolid Nodules

(2016) Rowena Yip et al.   RADIOLOGY

Low-Dose CT Screening for Lung Cancer: Computer-aided Detection of Missed Lung Cancers

(2016) Mingzhu Liang et al.   RADIOLOGY

Efficacy of low-dose computed tomography screening for lung cancer: the current state of evidence of mortality reduction

(2016) Motoyasu Sagawa et al.   SURGERY TODAY

Implementation planning for lung cancer screening: five major challenges

(2016) John K Field et al.   Lancet Respiratory Medicine

Lung cancer screening: latest developments and unanswered questions

(2016) Carlijn M van der Aalst et al.   Lancet Respiratory Medicine

Long-Term Follow-up Results of the DANTE Trial, a Randomized Study of Lung Cancer Screening with Spiral Computed Tomography

(2015) Maurizio Infante et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Solitary Pure Ground-Glass Nodules 5 mm or Smaller: Frequency of Growth

(2015) Ryutaro Kakinuma et al.   RADIOLOGY

British Thoracic Society guidelines for the investigation and management of pulmonary nodules: accredited by NICE

(2015) M E J Callister et al.   THORAX

UK Lung Cancer RCT Pilot Screening Trial: baseline findings from the screening arm provide evidence for the potential implementation of lung cancer screening

(2015) J K Field et al.   THORAX

Barriers to uptake among high-risk individuals declining participation in lung cancer screening: a mixed methods analysis of the UK Lung Cancer Screening (UKLS) trial

(2015) Noor Ali et al.   BMJ Open

Lung Cancer Detectability by Test, Histology, Stage, and Gender: Estimates from the NLST and the PLCO Trials

(2014) K. ten Haaf et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The UK Lung Screen (UKLS): Demographic Profile of First 88,897 Approaches Provides Recommendations for Population Screening

(2014) F. E. McRonald et al.   Cancer Prevention Research

Impact of Lung Cancer Screening Results on Smoking Cessation

(2014) Martin C. Tammemägi et al.   JNCI-Journal of the National Cancer Institute

Lung cancer probability in patients with CT-detected pulmonary nodules: a prespecified analysis of data from the NELSON trial of low-dose CT screening

(2014) Nanda Horeweg et al.   LANCET ONCOLOGY

Cost-Effectiveness of CT Screening in the National Lung Screening Trial

(2014) William C. Black et al.   NEW ENGLAND JOURNAL OF MEDICINE

Smoking habits in the randomised Danish Lung Cancer Screening Trial with low-dose CT: final results after a 5-year screening programme

(2014) Haseem Ashraf et al.   THORAX

Predictive Accuracy of the Liverpool Lung Project Risk Model for Stratifying Patients for Computed Tomography Screening for Lung Cancer

(2013) Olaide Y. Raji et al.   ANNALS OF INTERNAL MEDICINE

Benefits and Harms of Computed Tomography Lung Cancer Screening Strategies: A Comparative Modeling Study for the U.S. Preventive Services Task Force

(2013) Harry J. de Koning et al.   ANNALS OF INTERNAL MEDICINE

The National Lung Screening Trial: Results stratified by demographics, smoking history, and lung cancer histology

(2013) Paul F. Pinsky et al.   CANCER

Lung cancer screening with CT: Evaluation of radiologists and different computer assisted detection software (CAD) as first and second readers for lung nodule detection at different dose levels

(2013) A. Christe et al.   EUROPEAN JOURNAL OF RADIOLOGY

European randomized lung cancer screening trials: Post NLST

(2013) John K. Field et al.   JOURNAL OF SURGICAL ONCOLOGY

Targeting of Low-Dose CT Screening According to the Risk of Lung-Cancer Death

(2013) Stephanie A. Kovalchik et al.   NEW ENGLAND JOURNAL OF MEDICINE

Selection Criteria for Lung-Cancer Screening

(2013) Martin C. Tammemägi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Probability of Cancer in Pulmonary Nodules Detected on First Screening CT

(2013) Annette McWilliams et al.   NEW ENGLAND JOURNAL OF MEDICINE

Results of Initial Low-Dose Computed Tomographic Screening for Lung Cancer

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

A Cost-Utility Analysis of Lung Cancer Screening and the Additional Benefits of Incorporating Smoking Cessation Interventions

(2013) Andrea C. Villanti et al.   PLoS One

Demonstration program of population-based lung cancer screening in China: Rationale and study design

(2013) Qinghua Zhou et al.   Thoracic Cancer

Randomized study on early detection of lung cancer with MSCT in Germany: study design and results of the first screening round

(2012) N. Becker et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

A decrease in lung cancer mortality following the introduction of low-dose chest CT screening in Hitachi, Japan

(2012) Takeshi Nawa et al.   LUNG CANCER

CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT

(2012) Zaigham Saghir et al.   THORAX

Development and Validation of a Clinical Prediction Model to Estimate the Probability of Malignancy in Solitary Pulmonary Nodules in Chinese People

(2011) Yun Li et al.   Clinical Lung Cancer

Screening by Chest Radiograph and Lung Cancer Mortality

(2011) Martin M. Oken et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

No Benefit for Consensus Double Reading at Baseline Screening for Lung Cancer with the Use of Semiautomated Volumetry Software

(2011) Ying Wang et al.   RADIOLOGY

Transient Part-Solid Nodules Detected at Screening Thin-Section CT for Lung Cancer: Comparison with Persistent Part-Solid Nodules

(2010) Sang Min Lee et al.   RADIOLOGY

The Danish Randomized Lung Cancer CT Screening Trial—Overall Design and Results of the Prevalence Round

(2009) Jesper H. Pedersen et al.   Journal of Thoracic Oncology

Management of Lung Nodules Detected by Volume CT Scanning

(2009) Rob J. van Klaveren et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Pittsburgh Lung Screening Study (PLuSS)

(2008) David O. Wilson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Design, recruitment and baseline results of the ITALUNG trial for lung cancer screening with low-dose CT

(2008) Andrea Lopes Pegna et al.   LUNG CANCER