TRIM37 controls cancer-specific vulnerability to PLK4 inhibition

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer

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Delineation of the frequency and boundary of chromosomal copy number variations in paediatric neuroblastoma

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Once and only once: mechanisms of centriole duplication and their deregulation in disease

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PLK4 is a microtubule-associated protein that self assembles promoting de novo MTOC formation

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Pan-cancer genome and transcriptome analyses of 1,699 paediatric leukaemias and solid tumours

(2018) Xiaotu Ma et al.   NATURE

Aurora-PLK1 cascades as key signaling modules in the regulation of mitosis

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Structure of TRAF Family: Current Understanding of Receptor Recognition

(2018) Hyun H. Park   Frontiers in Immunology

TRIMming down to TRIM37: Relevance to Inflammation, Cardiovascular Disorders, and Cancer in MULIBREY Nanism

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CFI-400945 is not a selective cellular PLK4 inhibitor

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Mechanisms of Mitotic Spindle Assembly

(2016) Sabine Petry   Annual Review of Biochemistry

Quantitative analysis of human centrosome architecture by targeted proteomics and fluorescence imaging

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53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration

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Neuroblastoma: Molecular Pathogenesis and Therapy

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InteractiVenn: a web-based tool for the analysis of sets through Venn diagrams

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Reversible centriole depletion with an inhibitor of Polo-like kinase 4

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Combining CRISPR/Cas9 and rAAV Templates for Efficient Gene Editing

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TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein

(2014) Sanchita Bhatnagar et al.   NATURE

Improved vectors and genome-wide libraries for CRISPR screening

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Polo-like kinases: structural variations lead to multiple functions

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Molecular basis for unidirectional scaffold switching of human Plk4 in centriole biogenesis

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Easy quantitative assessment of genome editing by sequence trace decomposition

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Pericentriolar material structure and dynamics

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Acentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryo

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Loss of centrioles causes chromosomal instability in vertebrate somatic cells

(2013) Joo-Hee Sir et al.   JOURNAL OF CELL BIOLOGY

Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication

(2013) K. F. Sonnen et al.   JOURNAL OF CELL SCIENCE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152

(2013) T.-S. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

Differential expression analysis for sequence count data

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