Mechanics of a multilayer epithelium instruct tumour architecture and function

Liquid-liquid phase separation drives skin barrier formation

(2020) Felipe Garcia Quiroz et al.   SCIENCE

Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis

(2019) Hendrik A. Messal et al.   NATURE

Adaptive F-Actin Polymerization and Localized ATP Production Drive Basement Membrane Invasion in the Absence of MMPs

(2019) Laura C. Kelley et al.   DEVELOPMENTAL CELL

KLHL16 Degrades Epidermal Keratins

(2018) Fanny Büchau et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mechanisms and impact of altered tumour mechanics

(2018) Hamid Mohammadi et al.   NATURE CELL BIOLOGY

From morphogen to morphogenesis and back

(2017) Darren Gilmour et al.   NATURE

Building collagen IV smart scaffolds on the outside of cells

(2017) Kyle L. Brown et al.   PROTEIN SCIENCE

Coupling organelle inheritance with mitosis to balance growth and differentiation

(2017) Amma Asare et al.   SCIENCE

Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

(2017) Alexandros Glentis et al.   Nature Communications

Organ sculpting by patterned extracellular matrix stiffness

(2017) Justin Crest et al.   eLife

Quantitative Morphology of Epithelial Folds

(2016) Nick Štorgel et al.   BIOPHYSICAL JOURNAL

WNT-SHH Antagonism Specifies and Expands Stem Cells prior to Niche Formation

(2016) Tamara Ouspenskaia et al.   CELL

Wdr1-mediated cell shape dynamics and cortical tension are essential for epidermal planar cell polarity

(2015) Chen Luxenburg et al.   NATURE CELL BIOLOGY

Actomyosin networks and tissue morphogenesis

(2014) Akankshi Munjal et al.   DEVELOPMENT

Local and global dynamics of the basement membrane during branching morphogenesis require protease activity and actomyosin contractility

(2014) Jill S. Harunaga et al.   DEVELOPMENTAL BIOLOGY

The extracellular matrix modulates the hallmarks of cancer

(2014) M. W. Pickup et al.   EMBO REPORTS

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

(2014) Ovijit Chaudhuri et al.   NATURE MATERIALS

ECM-modulated cellular dynamics as a driving force for tissue morphogenesis

(2013) William P Daley et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

RNAi screens in mice identify physiological regulators of oncogenic growth

(2013) Slobodan Beronja et al.   NATURE

A unique covalent bond in basement membrane is a primordial innovation for tissue evolution

(2013) A. L. Fidler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Hedgehog pathway inhibition and the race against tumor evolution

(2012) Scott X. Atwood et al.   JOURNAL OF CELL BIOLOGY

Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions

(2012) Ashley C Brown et al.   JOURNAL OF PATHOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation

(2010) Mindy C DeRouen et al.   BMC DEVELOPMENTAL BIOLOGY

Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos

(2010) Slobodan Beronja et al.   NATURE MEDICINE

Endogenous expression of HrasG12V induces developmental defects and neoplasms with copy number imbalances of the oncogene

(2009) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH