New Advances in the Synthetic Application of Enantiomeric 1-Phenylethylamine (α-PEA): Privileged Chiral Inducer and Auxiliary

Regioselective and Stereodivergent Synthesis of Enantiomerically Pure Vic-Diamines from Chiral β-Amino Alcohols with 2-Pyridyl and 6-(2,2′-Bipyridyl) Moieties

(2020) Marzena Wosińska-Hrydczuk et al.   MOLECULES

An effective method for the determination of the enantio-purity of L-α-glycerophosphocholine (L-α-GPC)

(2020) Lorenzo de Ferra et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Copper-Catalyzed Asymmetric Arylation of N-Heteroaryl Aldimines via an Elementary Step of 1,4-Insertion

(2019) Jianrong Steve Zhou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The self-disproportionation of enantiomers (SDE): the effect of scaling down, potential problems vs. prospective applications, possible new occurrences, and unrealized opportunities?

(2019) Jianlin Han et al.   ELECTROPHORESIS

Chiral Tetraoxacalix[2]arene[2]triazine-based Organocatalysts for Enantioselective Aldol Reactions

(2019) Hayriye Nevin Genc et al.   TETRAHEDRON LETTERS

Synthesis of the Natural Product Iotrochamide B

(2019) S. Y. Wang et al.   CHEMISTRY OF NATURAL COMPOUNDS

Enantiopure 4‐oxazolin‐2‐ones and 4‐methylene‐2‐oxazolidinones as chiral building blocks in a divergent asymmetric synthesis of heterocycles

(2019) Blanca M. Santoyo et al.   CHIRALITY

Indolylglycines Backbones in the Synthesis of Enantiopure 3,3-Spiroindolenines, Indolyl Tetracyclic Hemiaminals, and 3-Indolyl-maleimides Frameworks

(2019) Jozef Markus et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2-Oxiranyl-pyridines: Synthesis and Regioselective Epoxide Ring Openings with Chiral Amines as a Route to Chiral Ligands

(2019) Marzena Wosińska-Hrydczuk et al.   HETEROATOM CHEMISTRY

Highly Diastereo- and Enantioselective Ir-Catalyzed Hydrogenation of 2,3-Disubstituted Quinolines with Structurally Fine-Tuned Phosphine–Phosphoramidite Ligands

(2019) Xin-Hu Hu et al.   ORGANIC LETTERS

Asymmetric Synthesis of 1-Phenylethylamine from Styrene via Combined Wacker-Oxidation and Enzymatic Reductive Amination

(2018) Florian Uthoff et al.   JOURNAL OF ORGANIC CHEMISTRY

Optimization of 2-alkoxyacetates as acylating agent for enzymatic kinetic resolution of chiral amines

(2018) Márk Oláh et al.   TETRAHEDRON

The enzymatic resolution of 1-(4-chlorophenyl)ethylamine by Novozym 435 to prepare a novel triazolopyrimidine herbicide

(2018) Yinjun Zhang et al.   CHIRALITY

Optically Active 2,7,10,15-Tetrahydroxytetraphenylene: Clathrates with Both Enantiomers of 1-Phenylethylamine and Their Stability

(2018) Hiroto Kaku et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Mechanoenzymatic resolution of racemic chiral amines, a green technique for the synthesis of pharmaceutical building blocks

(2018) Mario Pérez-Venegas et al.   TETRAHEDRON

Organocatalysts Effect on the Stereoselectivity of [2,3]-Wittig Rearrangement

(2018) Tibor Peňaška et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Self-Disproportionation of Enantiomers (SDE) via achiral gravity-driven column chromatography of N -fluoroacyl-1-phenylethylamines

(2017) Alicja Wzorek et al.   JOURNAL OF FLUORINE CHEMISTRY

Zinc and aluminum complexes of chiral ligands: Synthesis, characterization and application to rac-lactide polymerization

(2017) Bin Jia et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Iron catalyzed diastereoselective hydrogenation of chiral imines

(2017) D. Brenna et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and utilization of optically active α-aminophosphonate derivatives by Kabachnik-Fields reaction

(2017) Erika Bálint et al.   TETRAHEDRON

Asymmetric aminocarbonylation of iodoalkenes in the presence of α-phenylethylamine as an N -nucleophile

(2017) Gábor Mikle et al.   TETRAHEDRON-ASYMMETRY

Stereoselective Metal-Free Reduction of Chiral Imines in Batch and Flow Mode: A Convenient Strategy for the Synthesis of Chiral Active Pharmaceutical Ingredients

(2016) Davide Brenna et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Asymmetric syntheses of (−)-hastanecine, (−)-turneforcidine and (−)-platynecine

(2016) Marta Brambilla et al.   TETRAHEDRON

Asymmetric syntheses of the 1-hydroxymethyl-2-hydroxy substituted pyrrolizidines (−)-macronecine, (−)-petasinecine, (−)-1- epi -macronecine, (+)-1- epi -petasinecine and (+)-2- epi -rosmarinecine

(2016) Marta Brambilla et al.   TETRAHEDRON

Crystallization-based resolution of 1,4-benzodioxane-2-carboxylic acid enantiomers via diastereomeric 1-phenylethylamides

(2016) Laura Fumagalli et al.   TETRAHEDRON LETTERS

Enantiomeric Enrichmentsviathe Self-Disproportionation of Enantiomers (SDE) by Achiral, Gravity-Driven Column Chromatography: a Case Study UsingN-(1-Phenylethyl)acetamide for Optimizing the Enantiomerically Pure Yield and Magnitude of the SDE

(2015) Alicja Wzorek et al.   HELVETICA CHIMICA ACTA

Chiral Recognition Studies of α-(Nonafluoro-tert-butoxy)carboxylic Acids by NMR Spectroscopy

(2015) Anikó Nemes et al.   JOURNAL OF ORGANIC CHEMISTRY

Practical, Asymmetric Route to Sitagliptin and Derivatives: Development and Origin of Diastereoselectivity

(2015) Osvaldo Gutierrez et al.   ORGANIC LETTERS

Enantioselective addition of diethylzinc to aldehydes catalyzed by (R)-1-phenylethylamine-derived 1,4-amino alcohols

(2015) Masatoshi Asami et al.   TETRAHEDRON

Imidazolidinone based chiral auxiliary mediated acetate aldol reactions of isatin derivatives and stereoselective synthesis of 3-substituted-3-hydroxy-2-oxindoles

(2015) Mukesh Gangar et al.   TETRAHEDRON LETTERS

Direct asymmetric aldol reactions catalysed by trans-4-hydroxy-(S)-prolinamide in solvent-free conditions

(2015) Geeta Devi Yadav et al.   TETRAHEDRON-ASYMMETRY

A comprehensive examination of the self-disproportionation of enantiomers (SDE) of chiral amides via achiral, laboratory-routine, gravity-driven column chromatography

(2015) Yuya Suzuki et al.   RSC Advances

Synthesis and Characterization of Chiral Guanidines und Guanidinium Salts Derived from 1-Phenylethylamine

(2015) Amélie Castiglia et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES

Cutting Short the Asymmetric Synthesis of the Ramatroban Precursor by Employing ω-Transaminases

(2014) Eduardo Busto et al.   ADVANCED SYNTHESIS & CATALYSIS

A Simple Method for Resolution ofEndo-/Exo-Monoesters ofTrans-Norborn-5-Ene-2,3-Dicarboxylic Acids Into Their Enantiomers

(2014) Vitaly N. Kovalenko et al.   CHIRALITY

Synthesis of (+)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic Acid, a Diastereoselective Approach

(2014) Ilona Bułyszko et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Terminology Related to the Phenomenon ‘Self-Disproportionation of Enantiomers’ (SDE)

(2014) Vadim A. Soloshonok et al.   HELVETICA CHIMICA ACTA

Electrochemical Access to 8-(1-Phenyl-ethyl)-1,4-dioxa-8-aza-spiro[4.5]decane-7-carbonitrile. Application to the Asymmetric Syntheses of (+)-Myrtine and Alkaloid (+)-241D

(2014) Van Ha Vu et al.   JOURNAL OF ORGANIC CHEMISTRY

Chemoenzymatic Dynamic Kinetic Resolution of Primary Amines Using a Recyclable Palladium Nanoparticle Catalyst Together with Lipases

(2014) Karl P. J. Gustafson et al.   JOURNAL OF ORGANIC CHEMISTRY

Design and synthesis of (S)- and (R)-α-(phenyl)ethylamine-derived NH-type ligands and their application for the chemical resolution of α-amino acids

(2014) Ryosuke Takeda et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Solvent-Free Synthesis of a Secondary N-Benzhydrylamine as a Chiral Reagent for Asymmetric Deprotonation of Bicyclic N-Benzylamino Ketones

(2014) Aneta Nodzewska et al.   SYNTHESIS-STUTTGART

Diastereoselective Approach tocis-4-Methyl/thiol-Pipecolic Esters Based on RCM Reaction and Conjugate Michael Addition

(2014) Araceli Zárate et al.   SYNTHETIC COMMUNICATIONS

Enantioresolution of 2-methoxy-2-(1-naphtyl)propionic acid using diastereomeric salt formation with chiral phenylethylamine

(2014) Miho Kusakari et al.   TETRAHEDRON LETTERS

Preparation of (−)-(R)-2-(2,3,4,5,6-pentafluorophenoxy)-2-(phenyl-d5)acetic acid: an efficient 1H NMR chiral solvating agent for direct enantiomeric purity evaluation of quinoline-containing antimalarial drugs

(2014) Maria Maddalena Cavalluzzi et al.   TETRAHEDRON-ASYMMETRY

Enantioselective Synthesis of cis-3-Fluoropiperidin-4-ol, a Building Block for Medicinal Chemistry

(2013) Simon J. Shaw et al.   JOURNAL OF ORGANIC CHEMISTRY

Chemical approach for interconversion of (S)- and (R)-α-amino acids

(2013) Alexander E. Sorochinsky et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Ethyl acetate as an acyl donor in the continuous flow kinetic resolution of (±)-1-phenylethylamine catalyzed by lipases

(2013) Amanda S. de Miranda et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Asymmetric syntheses of (−)-isoretronecanol and (−)-trachelantamidine

(2013) Marta Brambilla et al.   TETRAHEDRON

Application of acyclic chiral auxiliaries on alkylation reactions

(2013) Monserrat H. Garduño-Castro et al.   TETRAHEDRON LETTERS

Synthesis of 1,3-aminonaphthols by diastereoselective Betti-type aminoalkylation of dihydroxy naphthalenes; diastereoselectivity, absolute configuration, and application

(2013) Maya Marinova et al.   TETRAHEDRON-ASYMMETRY

Optically Active α-Phenylethylamine as Efficient Organocatalyst in the Solvent-free Reactions Between 2,3-Butanedione and Conjugated Nitroolefins

(2012) Fulvia Felluga et al.   CHIRALITY

Resolution of 2-chloromandelic acid with (R)-(+)-N-benzyl-1-phenylethylamine: chiral discrimination mechanism

(2012) Yangfeng Peng et al.   CHIRALITY

Asymmetric Synthesis of Potent and Selective σ1Receptor Ligands with Tetrahydro-3-benzazepine Scaffold

(2012) Soumya Sarkar et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Reversal of Selectivity in Acetate Aldol Reactions of N-Acetyl-(S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one

(2012) Gopal L. Khatik et al.   ORGANIC LETTERS

D3-Trishomocubane-4-carboxylic Acid as a New Chiral Building Block: Synthesis and Absolute Configuration

(2012) Dmitriy Volochnyuk et al.   SYNTHESIS-STUTTGART

Self-disproportionation of enantiomers of non-racemic chiral amine derivatives through achiral chromatography

(2012) Tsuyoshi Nakamura et al.   TETRAHEDRON

Asymmetric synthesis of (−)-(1R,7aS)-absouline

(2012) Stephen G. Davies et al.   TETRAHEDRON

Solvent-free kinetic resolution of primary amines catalyzed by Candida antarctica lipase B: effect of immobilization and recycling stability

(2012) Mari Päiviö et al.   TETRAHEDRON-ASYMMETRY

Preparation of 2-amino-2-C-glycosyl-acetonitriles from C-glycosyl aldehydes by Strecker reaction

(2011) Szabolcs Sipos et al.   CARBOHYDRATE RESEARCH

General Strategy for Large-Scale Synthesis of (+)-Rivastigmine and (+)-NPS R-568

(2011) Ramakrishna Rao et al.   SYNTHETIC COMMUNICATIONS

Resolution of enantiomers of [α-hydroxy-(o-chlorophenyl)methyl]phosphinic acid via diastereomeric salt formation with enantiopure 1-phenylethylamines

(2011) Babak Kaboudin et al.   TETRAHEDRON-ASYMMETRY

New chiral amino alcohol ligands derived from 1-phenylethylamine for efficient Ru-catalyzed asymmetric transfer hydrogenation

(2011) Mei-Ling Han et al.   TETRAHEDRON-ASYMMETRY

The resolution of trans-2,2-dichloro-3-methylcyclopropanecarboxylic acid via crystallization of its salts with (+)- and (−)-α-phenylethylamine, and the transformation of the resulting enantiomers into (R)- and (S)-dimethyl 2-methylsuccinates

(2011) Vitaly N. Kovalenko et al.   TETRAHEDRON-ASYMMETRY

Optically active imidazoles derived from enantiomerically pure trans-1,2-diaminocyclohexane

(2011) Grzegorz Mlostoń et al.   TETRAHEDRON-ASYMMETRY

Novel stereoselective synthesis of 2,3-dihydro-1H-benzo[f]chromen-3-amine derivatives through a one-pot three-component reaction

(2011) Cristina Cimarelli et al.   TETRAHEDRON-ASYMMETRY

Development of dynamic kinetic resolution on large scale for (±)-1-phenylethylamine

(2010) Lisa K Thalén et al.   Beilstein Journal of Organic Chemistry

Structural influence of chiral tertiary aminonaphthol ligands on the asymmetric phenyl transfer to aromatic aldehydes

(2010) Hui Wei et al.   CHIRALITY

Solvent-induced chirality control in the enantioseparation of 1-phenylethylamine via diastereomeric salt formation

(2010) Koichi Kodama et al.   CHIRALITY

Chiral 1-phenylethylamine-derived phosphine-phosphoramidite ligands for highly enantioselective Rh-catalyzed hydrogenation of β-(acylamino)acrylates: significant effect of substituents on 3,3′-positions of binaphthyl moiety

(2010) Xiao-Mao Zhou et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Separation of racemic salycylaldehydes containing isobornyl substituent using (R)-1-phenylethylamine

(2010) E. V. Buravlev et al.   RUSSIAN JOURNAL OF ORGANIC CHEMISTRY

Novel ligands based on bromosubstituted hydroxycarbonyl [2.2]paracyclophane derivatives: synthesis and application in asymmetric catalysis

(2010) Natalia V. Vorontsova et al.   TETRAHEDRON-ASYMMETRY

Readily available chiral phosphine–aminophosphine ligands derived from 1-phenylethylamine for Rh-catalyzed enantioselective hydrogenations

(2010) Xiao-Mao Zhou et al.   TETRAHEDRON-ASYMMETRY

A general protocol for creating high-throughput screening assays for reaction yield and enantiomeric excess applied to hydrobenzoin

(2009) S. H. Shabbir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

(S)-(−)-α-Methylbenzylamine as chiral auxiliary in the synthesis of (+)-lortalamine

(2008) Jolanta Pawłowska et al.   MONATSHEFTE FUR CHEMIE