MALDI-HRMS Imaging Maps the Localization of Skyrin, the Precursor of Hypericin, and Pathway Intermediates in Leaves of Hypericum Species

Isolation, Characterization and Targeted Metabolic Evaluation of Endophytic Fungi Harbored in 14 Seed-Derived Hypericum Species

(2020) Jana Henzelyová et al.   PLANTA MEDICA

Discovery of key regulators of dark gland development and hypericin biosynthesis in St. John's Wort ( Hypericum perforatum )

(2019) Paride Rizzo et al.   PLANT BIOTECHNOLOGY JOURNAL

Host metabolite producing endophytic fungi isolated from Hypericum perforatum

(2019) Aruna Vigneshwari et al.   PLoS One

Role of secondary metabolites in plant defense against pathogens

(2018) Madiha Zaynab et al.   MICROBIAL PATHOGENESIS

Phenotyping the genus Hypericum by secondary metabolite profiling: emodin vs. skyrin, two possible key intermediates in hypericin biosynthesis

(2018) Katarína Kimáková et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Targeted metabolomic profiling reveals interspecific variation in the genus Hypericum in response to biotic elicitors

(2018) Miroslava Bálintová et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Hypericum perforatum: Synthesis of Active Principles during Flowering and Fruitification—Novel Aspects of Biological Potential

(2017) Nebojša Kladar et al.   Evidence-based Complementary and Alternative Medicine

Linking secondary metabolites to biosynthesis genes in the fungal endophyte Cyanodermella asteris : The anti-cancer bisanthraquinone skyrin

(2017) Linda Jahn et al.   JOURNAL OF BIOTECHNOLOGY

Chemometric evaluation of hypericin and related phytochemicals in 17 in vitro cultured Hypericum species, hairy root cultures and hairy root-derived transgenic plants

(2017) Katarína Nigutová et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

A new dimeric anthraquinone from endophyticTalaromycessp. YE3016

(2016) Xiao-Song Xie et al.   NATURAL PRODUCT RESEARCH

Interspecific variation in localization of hypericins and phloroglucinols in the genusHypericumas revealed by desorption electrospray ionization mass spectrometry imaging

(2016) Andrea Kucharíková et al.   PHYSIOLOGIA PLANTARUM

Comparative Transcriptome Reconstruction of Four Hypericum Species Focused on Hypericin Biosynthesis

(2016) Miroslav Soták et al.   Frontiers in Plant Science

Crystal Structure of Hyp-1, a Hypericum perforatum PR-10 Protein, in Complex with Melatonin

(2016) Joanna Sliwiak et al.   Frontiers in Plant Science

Hypericin in the Light and in the Dark: Two Sides of the Same Coin

(2016) Zuzana Jendželovská et al.   Frontiers in Plant Science

Molecular Cloning and Expression Analysis of hyp-1 Type PR-10 Family Genes in Hypericum perforatum

(2016) Katja Karppinen et al.   Frontiers in Plant Science

Occurrence and Distribution of Phytochemicals in the Leaves of 17 In vitro Cultured Hypericum spp. Adapted to Outdoor Conditions

(2016) Andrea Kucharíková et al.   Frontiers in Plant Science

Spatial chemo-profiling of hypericin and related phytochemicals in Hypericum species using MALDI-HRMS imaging

(2015) Souvik Kusari et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Polyphenols: From Plants to a Variety of Food and Nonfood Uses

(2015) Véronique Cheynier et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

MYB Transcription Factors as Regulators of Phenylpropanoid Metabolism in Plants

(2015) Jingying Liu et al.   Molecular Plant

Endophytes Are Hidden Producers of Maytansine in Putterlickia Roots

(2014) Souvik Kusari et al.   JOURNAL OF NATURAL PRODUCTS

Thehyp-1gene is not a limiting factor for hypericin biosynthesis in the genusHypericum

(2010) Ján Košuth et al.   FUNCTIONAL PLANT BIOLOGY

Crystal structure of Hyp-1, a St. John’s wort protein implicated in the biosynthesis of hypericin

(2009) Karolina Michalska et al.   JOURNAL OF STRUCTURAL BIOLOGY

Matrix-free UV-laser desorption/ionization (LDI) mass spectrometric imaging at the single-cell level: distribution of secondary metabolites of Arabidopsis thaliana and Hypericum species

(2009) Dirk Hölscher et al.   PLANT JOURNAL

An Endophytic Fungus fromHypericum perforatumthat Produces Hypericin

(2008) Souvik Kusari et al.   JOURNAL OF NATURAL PRODUCTS