Neonatal Sevoflurane Exposure Impairs Learning and Memory by the Hypermethylation of Hippocampal Synaptic Genes

Maternal Obesity as a Risk Factor for Brain Development and Mental Health in the Offspring

(2020) Francesca Cirulli et al.   NEUROSCIENCE

Resveratrol Mitigates Sevoflurane-Induced Neurotoxicity by the SIRT1-Dependent Regulation of BDNF Expression in Developing Mice

(2020) Xiaole Tang et al.   Oxidative Medicine and Cellular Longevity

Immunogold labeling of synaptic vesicle proteins in developing hippocampal neurons

(2020) Jung-Hwa Tao-Cheng   Molecular Brain

Metformin attenuates sevoflurane-induced neurocognitive impairment through AMPK-ULK1-dependent autophagy in aged mice

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AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic Excitability and Procedural Memory Formation

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Dexmedetomidine reduced sevoflurane-induced neurodegeneration and long-term memory deficits in neonatal rats

(2019) Toru Goyagi   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Sevoflurane Exposure Results in Sex-Specific Transgenerational Upregulation of Target IEGs in the Subiculum

(2019) Shelby E. Chastain-Potts et al.   MOLECULAR NEUROBIOLOGY

Early exposure to general anesthesia impairs social and emotional development in rats

(2019) Paolo Diana et al.   MOLECULAR NEUROBIOLOGY

Epigenetic programming—The important first 1000 days

(2019) Agnes Linnér et al.   ACTA PAEDIATRICA

Sevoflurane Impairs Short-Term Memory by Affecting PSD-95 and AMPA Receptor in the Hippocampus of a Mouse Model

(2019) Yuan Jiao et al.   BEHAVIOURAL NEUROLOGY

Sirtuin 2 Inhibition Attenuates Sevoflurane-Induced Learning and Memory Deficits in Developing Rats via Modulating Microglial Activation

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Synaptic biomarker reduction and impaired cognition in the sub-chronic PCP mouse model for schizophrenia

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Methylation in Syn and Psd95 genes underlie the inhibitory effect of oxytocin on oxycodone-induced conditioned place preference

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Neuropsychological and Behavioral Outcomes after Exposure of Young Children to Procedures Requiring General Anesthesia

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Role of epigenetic mechanisms in transmitting the effects of neonatal sevoflurane exposure to the next generation of male, but not female, rats

(2018) L.-S. Ju et al.   BRITISH JOURNAL OF ANAESTHESIA

Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise

(2018) Ziyi Wu et al.   Frontiers in Cellular Neuroscience

PON1 DNA methylation and neurobehavior in Mexican-American children with prenatal organophosphate exposure

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Neonatal exposure to sevoflurane caused cognitive deficits by dysregulating SK2 channels and GluA2-lacking AMPA receptors in juvenile rat hippocampus

(2018) Xiangdi Yu et al.   NEUROPHARMACOLOGY

Association between DNA methylation in cord blood and maternal smoking: The Hokkaido Study on Environment and Children’s Health

(2018) Kunio Miyake et al.   Scientific Reports

Effects of 5-Aza on p-Y1472 NR2B related to learning and memory in the mouse hippocampus

(2018) Xiaolu Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Elective caesarean delivery and offspring’s cognitive impairment: Implications of methylation alteration in hippocampus glucocorticoid signaling genes

(2018) Kun Huang et al.   BRAIN RESEARCH BULLETIN

Multiple sevoflurane anesthesia in pregnant mice inhibits neurogenesis of fetal hippocampus via repressing transcription factor Pax6

(2017) Fang Fang et al.   LIFE SCIENCES

Role of DNA methylation in perinatal nicotine-induced development of heart ischemia-sensitive phenotype in rat offspring

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Epigenetic Alterations and Prenatal Maternal Depression

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Learning, memory and synaptic plasticity in hippocampus in rats exposed to sevoflurane

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Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood

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Early-life single-episode sevoflurane exposure impairs social behavior and cognition later in life

(2016) Daisy Lin et al.   Brain and Behavior

Neurobehavioural abnormalities induced by repeated exposure of neonatal rats to sevoflurane can be aggravated by social isolation and enrichment deprivation initiated after exposure to the anaesthetic

(2015) M.Q. Zhang et al.   BRITISH JOURNAL OF ANAESTHESIA

Hypermethylation of Hippocampal Synaptic Plasticity-Related genes is Involved in Neonatal Sevoflurane Exposure-Induced Cognitive Impairments in Rats

(2015) Ling-sha Ju et al.   NEUROTOXICITY RESEARCH

Effects of sevoflurane on learning, memory, and expression of pERK1/2 in hippocampus in neonatal rats

(2014) X. YU et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Sevoflurane-Induced Down-regulation of Hippocampal Oxytocin and Arginine Vasopressin Impairs Juvenile Social Behavioral Abilities

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Measuring epigenetics as the mediator of gene/environment interactions in DOHaD

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Characterization of CpG island DNA methylation of impairment-related genes in a rat model of cognitive aging

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Cognitive and Behavioral Outcomes After Early Exposure to Anesthesia and Surgery

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