β-catenin represses miR455-3p to stimulate m6A modification of HSF1 mRNA and promote its translation in colorectal cancer

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer

(2019) Liyuan Zhu et al.   Cell Death & Disease

Phosphorylation of HSF1 by PIM2 induces PD-L1 expression and promotes tumor growth in breast cancer

(2019) Tingting Yang et al.   CANCER RESEARCH

α-Ketoglutarate links p53 to cell fate during tumour suppression

(2019) John P. Morris et al.   NATURE

Repression of MAP3K1 expression and JNK activity by canonical Wnt signaling

(2018) Qinghang Meng et al.   DEVELOPMENTAL BIOLOGY

N 6 -Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response

(2018) Jun Zhou et al.   MOLECULAR CELL

Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis

(2018) Jiaqiu Li et al.   MOLECULAR THERAPY

SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function

(2018) Yuzhang Du et al.   NUCLEIC ACIDS RESEARCH

mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis

(2018) Junho Choe et al.   NATURE

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing

(2017) Marek Bartosovic et al.   NUCLEIC ACIDS RESEARCH

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

N6-methyladenosine Modulates Messenger RNA Translation Efficiency

(2015) Xiao Wang et al.   CELL

m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency

(2015) Tong Chen et al.   Cell Stem Cell

Structure and Thermodynamics of N6-Methyladenosine in RNA: A Spring-Loaded Base Modification

(2015) Caroline Roost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Towards a molecular understanding of microRNA-mediated gene silencing

(2015) Stefanie Jonas et al.   NATURE REVIEWS GENETICS

miR455 is linked to hypoxia signaling and is deregulated in preeclampsia

(2014) S Lalevée et al.   Cell Death & Disease

Wnt-Mediated Repression via Bipartite DNA Recognition by TCF in the Drosophila Hematopoietic System

(2014) Chen U. Zhang et al.   PLoS Genetics

Mutational landscape and significance across 12 major cancer types

(2013) Cyriac Kandoth et al.   NATURE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Multiple functions of the noncanonical Wnt pathway

(2013) Eva Gómez-Orte et al.   TRENDS IN GENETICS

Targeting the Wnt Pathway in Synovial Sarcoma Models

(2013) W. Barham et al.   Cancer Discovery

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis

(2012) Joseph Rosenbluh et al.   CELL

β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3′-UTR and interacts with HuR in colon cancer cells

(2012) Inae Kim et al.   NUCLEIC ACIDS RESEARCH

β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

(2011) Helena J M Smartt et al.   GUT

Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin

(2011) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of protein-DNA interactions by penalized multivariate regression

(2009) L. Zamdborg et al.   NUCLEIC ACIDS RESEARCH

Getting to the Root of miRNA-Mediated Gene Silencing

(2008) Ana Eulalio et al.   CELL

A Wnt-fall for Gene Regulation: Repression

(2008) N. P. Hoverter et al.   Science Signaling