Masters of asymmetry – lessons and perspectives from 50 years of septins

Mapping axon initial segment structure and function by multiplexed proximity biotinylation

(2020) Hamdan Hamdan et al.   Nature Communications

Cdc24 interacts with the septins to create a positive feedback during bud site assembly in yeast

(2020) Julian Chollet et al.   JOURNAL OF CELL SCIENCE

A complete compendium of crystal structures for the human SEPT3 subgroup reveals functional plasticity at a specific septin interface

(2020) Danielle Karoline Silva do Vale Castro et al.   IUCrJ

A septin-Hof1 scaffold at the yeast bud neck binds and organizes actin cables

(2020) Mikael V. Garabedian et al.   MOLECULAR BIOLOGY OF THE CELL

An amphipathic helix enables septins to sense micrometer-scale membrane curvature

(2019) Kevin S. Cannon et al.   JOURNAL OF CELL BIOLOGY

A SEPT1-based scaffold is required for Golgi integrity and function

(2019) Kyungyeun Song et al.   JOURNAL OF CELL SCIENCE

A revised order of subunits in mammalian septin complexes

(2019) Deborah C. Mendonça et al.   Cytoskeleton

Turning it inside out: The organization of human septin heterooligomers

(2019) Michael A. McMurray et al.   Cytoskeleton

Septin 2/6/7 complexes tune microtubule plus-end growth and EB1 binding in a concentration- and filament-dependent manner

(2019) Konstantinos Nakos et al.   MOLECULAR BIOLOGY OF THE CELL

Septins - active GTPases or just GTP-binding proteins?

(2018) Megha Abbey et al.   Cytoskeleton

Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin

(2018) Eva P. Karasmanis et al.   DEVELOPMENTAL CELL

Septins regulate the equatorial dynamics of the separation initiation network kinase Sid2p and glucan synthases to ensure proper cytokinesis

(2018) Shengnan Zheng et al.   FEBS Journal

Septin-dependent remodeling of cortical microtubule drives cell reshaping during epithelial wound healing

(2018) Asako Shindo et al.   JOURNAL OF CELL SCIENCE

Regulation of mechanotransduction: Emerging roles for septins

(2018) Maxine Lam et al.   Cytoskeleton

The last-born daughter cell contributes to division orientation of Drosophila larval neuroblasts

(2018) Nicolas Loyer et al.   Nature Communications

Septins Recognize and Entrap Dividing Bacterial Cells for Delivery to Lysosomes

(2018) Sina Krokowski et al.   Cell Host & Microbe

SUMOylation of human septins is critical for septin filament bundling and cytokinesis

(2017) David Ribet et al.   JOURNAL OF CELL BIOLOGY

Molecular Memory of Morphologies by Septins during Neuron Generation Allows Early Polarity Inheritance

(2017) Leila Boubakar et al.   NEURON

The step-wise pathway of septin hetero-octamer assembly in budding yeast

(2017) Andrew Weems et al.   eLife

Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments

(2017) P. Verdier-Pinard et al.   Scientific Reports

Mitochondria mediate septin cage assembly to promote autophagy ofShigella

(2016) Andrea Sirianni et al.   EMBO REPORTS

A role for septin 2 in Drp1‐mediated mitochondrial fission

(2016) Alessandro Pagliuso et al.   EMBO REPORTS

Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton

(2016) Andrew A. Bridges et al.   JOURNAL OF CELL BIOLOGY

Septins promote macropinosome maturation and traffic to the lysosome by facilitating membrane fusion

(2016) Lee Dolat et al.   JOURNAL OF CELL BIOLOGY

Cortical PAR polarity proteins promote robust cytokinesis during asymmetric cell division

(2016) Shawn N. Jordan et al.   JOURNAL OF CELL BIOLOGY

Roles of septins in prospore membrane morphogenesis and spore wall assembly in Saccharomyces cerevisiae

(2016) Lydia R. Heasley et al.   MOLECULAR BIOLOGY OF THE CELL

Septins guide microtubule protrusions induced by actin-depolymerizing toxins likeClostridium difficiletransferase (CDT)

(2016) Thilo Nölke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV

(2016) Abdellah Akil et al.   Nature Communications

Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration

(2016) Zhuo Gan et al.   Cell Systems

Septins and Generation of Asymmetries in Fungal Cells

(2015) Anum Khan et al.   Annual Review of Microbiology

The planar cell polarity effector protein Wdpcp (Fritz) controls epithelial cell cortex dynamics via septins and actomyosin

(2015) Tae Joo Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RGS Proteins and Septins Cooperate to Promote Chemotropism by Regulating Polar Cap Mobility

(2015) Joshua B. Kelley et al.   CURRENT BIOLOGY

Septin-Dependent Assembly of the Exocyst Is Essential for Plant Infection byMagnaporthe oryzae

(2015) Yogesh K. Gupta et al.   PLANT CELL

Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts

(2015) Fernando Calvo et al.   Cell Reports

Septins promote stress fiber–mediated maturation of focal adhesions and renal epithelial motility

(2014) Lee Dolat et al.   JOURNAL OF CELL BIOLOGY

Cell type–specific expression of SEPT3-homology subgroup members controls the subunit number of heteromeric septin complexes

(2014) Mikael E. Sellin et al.   MOLECULAR BIOLOGY OF THE CELL

Septins promote F-actin ring formation by crosslinking actin filaments into curved bundles

(2014) Manos Mavrakis et al.   NATURE CELL BIOLOGY

A Septin-Dependent Diffusion Barrier at Dendritic Spine Necks

(2014) Helge Ewers et al.   PLoS One

Septin assemblies form by diffusion-driven annealing on membranes

(2014) Andrew A. Bridges et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PCP and Septins Compartmentalize Cortical Actomyosin to Direct Collective Cell Movement

(2014) A. Shindo et al.   SCIENCE

A sphingolipid-dependent diffusion barrier confines ER stress to the yeast mother cell

(2014) Lori Clay et al.   eLife

Role of SAGA in the asymmetric segregation of DNA circles during yeast ageing

(2014) Annina Denoth-Lippuner et al.   eLife

Human septin isoforms and the GDP-GTP cycle

(2013) Eldar Zent et al.   BIOLOGICAL CHEMISTRY

Septin functions in organ system physiology and pathology

(2013) Lee Dolat et al.   BIOLOGICAL CHEMISTRY

Daughter Cell Identity Emerges from the Interplay of Cdc42, Septins, and Exocytosis

(2013) Satoshi Okada et al.   DEVELOPMENTAL CELL

Septin rings act as a template for myosin higher-order structures and inhibit redundant polarity establishment

(2013) C. Schneider et al.   JOURNAL OF CELL SCIENCE

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry

(2013) Sonia Sharma et al.   NATURE

Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton

(2013) Cheng Cui et al.   PLOS BIOLOGY

Possible role of a septin, SEPT1, in spreading in squamous cell carcinoma DJM-1 cells

(2012) Yoko Mizutani et al.   BIOLOGICAL CHEMISTRY

Septin-Driven Coordination of Actin and Microtubule Remodeling Regulates the Collateral Branching of Axons

(2012) Jianli Hu et al.   CURRENT BIOLOGY

Posttranslational modifications and assembly of septin heteropolymers and higher-order structures

(2012) Yainitza Hernández-Rodríguez et al.   CURRENT OPINION IN MICROBIOLOGY

The septin cytoskeleton facilitates membrane retraction during motility and blebbing

(2012) Julia K. Gilden et al.   JOURNAL OF CELL BIOLOGY

Regulation of the formin Bnr1 by septins anda MARK/Par1-family septin-associated kinase

(2012) Shawnna M. Buttery et al.   MOLECULAR BIOLOGY OF THE CELL

Septins: the fourth component of the cytoskeleton

(2012) Serge Mostowy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Septin-Mediated Plant Cell Invasion by the Rice Blast Fungus, Magnaporthe oryzae

(2012) Y. F. Dagdas et al.   SCIENCE

Septin-Containing Barriers Control the Differential Inheritance of Cytoplasmic Elements

(2012) Alan Michael Tartakoff et al.   Cell Reports

Evidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast

(2011) Carsten Wloka et al.   BIOLOGICAL CHEMISTRY

Artificial tethering to nuclear pores promotes partitioning of extrachromosomal DNA during yeast asymmetric cell division

(2011) Anton Khmelinskii et al.   CURRENT BIOLOGY

Submembranous septins as relatively stable components of actin-based membrane skeleton

(2011) Akari Hagiwara et al.   Cytoskeleton

Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia

(2011) Jonathan R. Bowen et al.   JOURNAL OF CELL BIOLOGY

Nuclear Geometry and Rapid Mitosis Ensure Asymmetric Episome Segregation in Yeast

(2010) Lutz R. Gehlen et al.   CURRENT BIOLOGY

Role of Septins in the Orientation of Forespore Membrane Extension during Sporulation in Fission Yeast

(2010) M. Onishi et al.   MOLECULAR AND CELLULAR BIOLOGY

A Septin Diffusion Barrier at the Base of the Primary Cilium Maintains Ciliary Membrane Protein Distribution

(2010) Q. Hu et al.   SCIENCE

The Annulus of the Mouse Sperm Tail Is Required to Establish a Membrane Diffusion Barrier That Is Engaged During the Late Steps of Spermiogenesis1

(2009) Susanna Kwitny et al.   BIOLOGY OF REPRODUCTION

Septins and the Lateral Compartmentalization of Eukaryotic Membranes

(2009) Fabrice Caudron et al.   DEVELOPMENTAL CELL

GTP-induced conformational changes in septins and implications for function

(2009) M. Sirajuddin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Septins: molecular partitioning and the generation of cellular asymmetry

(2009) Michael A McMurray et al.   Cell Division

Forchlorfenuron Alters Mammalian Septin Assembly, Organization, and Dynamics

(2008) Qicong Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial polarity requires septin coupling of vesicle transport to polyglutamylated microtubules

(2008) Elias T. Spiliotis et al.   JOURNAL OF CELL BIOLOGY

A mechanism for asymmetric segregation of age during yeast budding

(2008) Zhanna Shcheprova et al.   NATURE

Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility

(2008) Aaron J. Tooley et al.   NATURE CELL BIOLOGY

Saccharomyces cerevisiae septins: Supramolecular organization of heterooligomers and the mechanism of filament assembly

(2008) A. Bertin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA