Astrocytes from cortex and striatum show differential responses to mitochondrial toxin and BDNF: implications for protection of striatal neurons expressing mutant huntingtin

Region-Specific Neuroprotective Features of Astrocytes against Oxidative Stress Induced by 6-Hydroxydopamine

(2019) Masato Asanuma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rutin and Selenium Co-administration Reverse 3-Nitropropionic Acid-Induced Neurochemical and Molecular Impairments in a Mouse Model of Huntington’s Disease

(2019) Mohamed S. Abdelfattah et al.   NEUROTOXICITY RESEARCH

Astrocyte morphogenesis is dependent on BDNF signaling via astrocytic TrkB.T1

(2019) Leanne M Holt et al.   eLife

Neuroinflammation as a Common Feature of Neurodegenerative Disorders

(2019) Leonardo Guzman-Martinez et al.   Frontiers in Pharmacology

Astrocyte molecular signatures in Huntington’s disease

(2019) Blanca Diaz-Castro et al.   Science Translational Medicine

Astrocyte truncated-TrkB mediates BDNF antiapoptotic effect leading to neuroprotection

(2018) Julieta Saba et al.   JOURNAL OF NEUROCHEMISTRY

High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry

(2018) Susie Son et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Melanocortin 4 receptor activation protects striatal neurons and glial cells from 3-nitropropionic acid toxicity

(2018) Julieta Saba et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Astrocytes and the TGF-β1 Pathway in the Healthy and Diseased Brain: a Double-Edged Sword

(2018) Luan Pereira Diniz et al.   MOLECULAR NEUROBIOLOGY

Roles of p62 in BDNF-dependent autophagy suppression and neuroprotection against mitochondrial dysfunction in rat cortical neurons

(2017) Chia-Lin Wu et al.   JOURNAL OF NEUROCHEMISTRY

Truncated TrkB.T1-Mediated Astrocyte Dysfunction Contributes to Impaired Motor Function and Neuropathic Pain after Spinal Cord Injury

(2017) Jessica J. Matyas et al.   JOURNAL OF NEUROSCIENCE

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

(2017) Hua Chai et al.   NEURON

Resolving Astrocyte Heterogeneity in the CNS

(2017) W. Todd Farmer et al.   Frontiers in Cellular Neuroscience

Heterogeneous astrocytes: Active players in CNS

(2016) Xin Hu et al.   BRAIN RESEARCH BULLETIN

Excess cerebral TNF causing glutamate excitotoxicity rationalizes treatment of neurodegenerative diseases and neurogenic pain by anti-TNF agents

(2016) Ian A. Clark et al.   Journal of Neuroinflammation

Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice

(2016) R. Jiang et al.   JOURNAL OF NEUROSCIENCE

Astrocytes, therapeutic targets for neuroprotection and neurorestoration in ischemic stroke

(2016) Zhongwu Liu et al.   PROGRESS IN NEUROBIOLOGY

LPS-Primed Release of HMGB-1 from Cortical Astrocytes is Modulated Through PI3K/AKT Pathway

(2015) Ze-Feng Xie et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Melanocortin 4 receptor activates ERK-cFos pathway to increase brain-derived neurotrophic factor expression in rat astrocytes and hypothalamus

(2015) D. Ramírez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Diversity of astrocyte functions and phenotypes in neural circuits

(2015) Baljit S Khakh et al.   NATURE NEUROSCIENCE

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

Astrocytes in Neurodegenerative Disease: Table 1.

(2015) Hemali Phatnani et al.   Cold Spring Harbor Perspectives in Biology

Inhibition of soluble tumor necrosis factor is therapeutic in Huntington's disease

(2014) Han-Yun Hsiao et al.   HUMAN MOLECULAR GENETICS

Tumor Necrosis Factor Alpha: A Link between Neuroinflammation and Excitotoxicity

(2014) Gabriel Olmos et al.   MEDIATORS OF INFLAMMATION

GLT-1 transporter: An effective pharmacological target for various neurological disorders

(2014) Neha Soni et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

BDNF signaling and survival of striatal neurons

(2014) Maryna Baydyuk et al.   Frontiers in Cellular Neuroscience

Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS

(2013) Thomas Koeglsperger et al.   GLIA

BDNF prevents NMDA-induced toxicity in models of Huntington's disease: the effects are genotype specific and adenosine A2Areceptor is involved

(2013) Alberto Martire et al.   JOURNAL OF NEUROCHEMISTRY

Expression of mutant N-terminal huntingtin fragment (htt552-100Q) in astrocytes suppresses the secretion of BDNF

(2012) Linhui Wang et al.   BRAIN RESEARCH

Truncated TrkB: Beyond a dominant negative receptor

(2012) Barbara M. Fenner   CYTOKINE & GROWTH FACTOR REVIEWS

The Neuroprotective Functions of Transforming Growth Factor Beta Proteins

(2012) Arpád Dobolyi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Primary Cultures of Astrocytes: Their Value in Understanding Astrocytes in Health and Disease

(2012) Sofie C. Lange et al.   NEUROCHEMICAL RESEARCH

Development of a Method for the Purification and Culture of Rodent Astrocytes

(2011) Lynette C. Foo et al.   NEURON

Brain region-specific vulnerability of astrocytes in response to 3-nitropropionic acid is mediated by cytochrome c oxidase isoform expression

(2010) Magdalena Misiak et al.   CELL AND TISSUE RESEARCH

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

(2010) M. Faideau et al.   HUMAN MOLECULAR GENETICS

Early defect of transforming growth factor β1 formation in Huntington’s disease

(2010) Giuseppe Battaglia et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

3-Nitropropionic Acid as a Tool to Study the Mechanisms Involved in Huntington’s Disease: Past, Present and Future

(2010) Isaac Túnez et al.   MOLECULES

Reactive astrocytes as therapeutic targets for CNS disorders

(2010) Mary E. Hamby et al.   Neurotherapeutics

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

(2010) Chiara Zuccato et al.   PHYSIOLOGICAL REVIEWS

Brain-Derived Neurotrophic Factor (BDNF) has Proliferative Effects on Neural Stem Cells through the Truncated TRK-B Receptor, MAP Kinase, AKT, and STAT-3 Signaling Pathways

(2009) Omedul Islam et al.   CURRENT NEUROVASCULAR RESEARCH

Protective effects of brain-derived neurotrophic factor against neurotoxicity of 3-nitropropionic acid in rat cortical neurons

(2009) Chia-Lin Wu et al.   NEUROTOXICOLOGY

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE