p53 Hinders CRISPR/Cas9-Mediated Targeted Gene Disruption in Memory CD8 T Cells In Vivo

Recent advances in genome editing of stem cells for drug discovery and therapeutic application

(2020) Jaesuk Lee et al.   PHARMACOLOGY & THERAPEUTICS

CRISPR-engineered T cells in patients with refractory cancer

(2020) Edward A. Stadtmauer et al.   SCIENCE

Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies

(2020) Simone Nüssing et al.   JOURNAL OF IMMUNOLOGY

CRISPR/Cas9-based genome editing in the Era of CAR T cell immunotherapy

(2019) January Salas-Mckee et al.   Human Vaccines & Immunotherapeutics

The next generation of CRISPR–Cas technologies and applications

(2019) Adrian Pickar-Oliver et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiplexed CRISPR/Cas9 gene knockout with simple crRNA:tracrRNA co-transfection

(2019) Fehad J. Khan et al.   Cell and Bioscience

The Functional Requirement for CD69 in Establishment of Resident Memory CD8+ T Cells Varies with Tissue Location

(2019) Daniel A. Walsh et al.   JOURNAL OF IMMUNOLOGY

Therapeutic potential of CRISPR/Cas9 gene editing in engineered T‐cell therapy

(2019) Qianqian Gao et al.   Cancer Medicine

Hidden Caveat of Inducible Cre Recombinase

(2019) Makoto Kurachi et al.   IMMUNITY

CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma

(2019) Bryan D. Choi et al.   Journal for ImmunoTherapy of Cancer

Multiple homologous genes knockout (KO) by CRISPR/Cas9 system in rabbit

(2018) Huan Liu et al.   GENE

Understanding Subset Diversity in T Cell Memory

(2018) Stephen C. Jameson et al.   IMMUNITY

KLRG1 + Effector CD8 + T Cells Lose KLRG1, Differentiate into All Memory T Cell Lineages, and Convey Enhanced Protective Immunity

(2018) Dietmar Herndler-Brandstetter et al.   IMMUNITY

Optimized RNP transfection for highly efficient CRISPR/Cas9-mediated gene knockout in primary T cells

(2018) Akiko Seki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing

(2018) Xin Chen et al.   JOURNAL OF IMMUNOLOGY

p53 inhibits CRISPR–Cas9 engineering in human pluripotent stem cells

(2018) Robert J. Ihry et al.   NATURE MEDICINE

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response

(2018) Emma Haapaniemi et al.   NATURE MEDICINE

CRISPR, cancer, and p53

(2018) Leslie K. Ferrarelli   Science Signaling

Detecting and Avoiding Problems When Using the Cre–lox System

(2018) Allisa J. Song et al.   TRENDS IN GENETICS

CRISPR/Cas9 mediated targeting of multiple genes in Dictyostelium

(2018) Ryoya Sekine et al.   Scientific Reports

CRISPR, cancer, and p53

(2018) Leslie K. Ferrarelli   Science Signaling

Repeated Antigen Exposure Extends the Durability of Influenza-Specific Lung-Resident Memory CD8+ T Cells and Heterosubtypic Immunity

(2018) Natalija Van Braeckel-Budimir et al.   Cell Reports

CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review

(2018) Bagher Farhood et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions

(2018) Judd F. Hultquist et al.   Nature Protocols

Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases

(2017) Jonathan P. McNally et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of knock-in primary human T cells using Cas9 ribonucleoproteins

(2015) Kathrin Schumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiation sensitivity of human and murine peripheral blood lymphocytes, stem and progenitor cells

(2014) Daniel Heylmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Downmodulation of Tumor Suppressor p53 by T Cell Receptor Signaling Is Critical for Antigen-Specific CD4+ T Cell Responses

(2014) Masashi Watanabe et al.   IMMUNITY

CRISPR-Cas9-Mediated Single-Gene and Gene Family Disruption in Trypanosoma cruzi

(2014) D. Peng et al.   mBio

T cell responses: naïve to memory and everything in between

(2013) Nathan D. Pennock et al.   ADVANCES IN PHYSIOLOGY EDUCATION

Programmed Death-1 Shapes Memory Phenotype CD8 T Cell Subsets in a Cell-Intrinsic Manner

(2013) J. J. Charlton et al.   JOURNAL OF IMMUNOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Memory T Cell Subsets, Migration Patterns, and Tissue Residence

(2012) Scott N. Mueller et al.   Annual Review of Immunology

Development and validation of qualitative SYBR®Green Real-Time PCR for detection and discrimination of Listeria spp. and Listeria monocytogenes

(2012) Elodie Barbau-Piednoir et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88

(2011) A. H. Rahman et al.   BLOOD

Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection

(2011) Noah S Butler et al.   NATURE IMMUNOLOGY

Two-phase dynamics of p53 in the DNA damage response

(2011) X.-P. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of p53 in Cell Death and Human Cancers

(2011) Toshinori Ozaki et al.   Cancers

The NK receptor KLRG1 is dispensable for virus-induced NK and CD8+ T-cell differentiation and function in vivo

(2010) Carsten Gründemann et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Repetitive Antigen Stimulation Induces Stepwise Transcriptome Diversification but Preserves a Core Signature of Memory CD8+ T Cell Differentiation

(2010) Thomas C. Wirth et al.   IMMUNITY