Identification of pleiotropic loci underlying hip bone mineral density and trunk lean mass

Joint Association Analysis Identified 18 New Loci for Bone Mineral Density

(2019) Yu-Fang Pei et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

(2019) Adrienne Tin et al.   NATURE GENETICS

An atlas of genetic influences on osteoporosis in humans and mice

(2018) John A. Morris et al.   NATURE GENETICS

Association analysis identifies 65 new breast cancer risk loci

(2017) Kyriaki Michailidou et al.   NATURE

Identification of H3K4me1-associated proteins at mammalian enhancers

(2017) Andrea Local et al.   NATURE GENETICS

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

(2017) John P Kemp et al.   NATURE GENETICS

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

(2017) Diana Chang et al.   NATURE GENETICS

Osteosarcopenia: where bone, muscle, and fat collide

(2017) H. P. Hirschfeld et al.   OSTEOPOROSIS INTERNATIONAL

Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus

(2017) Carolina Medina-Gomez et al.   Nature Communications

Trunk lean mass and its association with 4 different measures of thoracic kyphosis in older community dwelling persons

(2017) J. Yamamoto et al.   PLoS One

Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture

(2015) Philip E. Stuart et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension

(2015) Xiaofeng Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Bone and muscle: Interactions beyond mechanical

(2015) Marco Brotto et al.   BONE

Associations of Abdominal Muscle Area with 4-Year Change in Coronary Artery Calcium Differ by Ethnicity among Post-Menopausal Women

(2015) Christina L. Wassel et al.   ETHNICITY & DISEASE

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

(2015) Hou‐Feng Zheng et al.   NATURE

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

(2015) Kyriaki Michailidou et al.   NATURE GENETICS

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Large-scale analysis reveals a functional single-nucleotide polymorphism in the 5′-flanking region ofPRDM16gene associated with lean body mass

(2014) Tomohiko Urano et al.   AGING CELL

FISH: fast and accurate diploid genotype imputation via segmental hidden Markov model

(2014) Lei Zhang et al.   BIOINFORMATICS

Efficient multivariate linear mixed model algorithms for genome-wide association studies

(2014) Xiang Zhou et al.   NATURE METHODS

Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent

(2013) L. Fernandez-Rhodes et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity

(2013) Y.-F. Pei et al.   HUMAN MOLECULAR GENETICS

Multistage genome-wide association meta-analyses identified two new loci for bone mineral density

(2013) Lei Zhang et al.   HUMAN MOLECULAR GENETICS

On Genome-Wide Association Studies and Their Meta-Analyses: Lessons Learned From Osteoporosis Studies

(2013) Yong-Jun Liu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association Between Common Variants Near the Melanocortin 4 Receptor Gene and Severe Antipsychotic Drug–Induced Weight Gain

(2012) Anil K. Malhotra   ARCHIVES OF GENERAL PSYCHIATRY

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Regulation of Lean Mass, Bone Mass, and Exercise Tolerance by the Central Melanocortin System

(2012) Theodore P. Braun et al.   PLoS One

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

(2012) Anthony G. Comuzzie et al.   PLoS One

Rapidly increasing rates of hip fracture in Beijing, China

(2011) Wei-Bo Xia et al.   JOURNAL OF BONE AND MINERAL RESEARCH

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

The Association Between Abdominal Body Composition and Vascular Calcification

(2011) Nicole E. Jensky et al.   Obesity

Genetic variants in the SOX6 gene are associated with bone mineral density in both Caucasian and Chinese populations

(2011) T.-L. Yang et al.   OSTEOPOROSIS INTERNATIONAL

Bivariate Genome-Wide Association Analyses of Femoral Neck Bone Geometry and Appendicular Lean Mass

(2011) Lu Sun et al.   PLoS One

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage

(2010) Peter Dy et al.   DEVELOPMENTAL BIOLOGY

An Association Test for Multiple Traits Based on the Generalized Kendall’s Tau

(2010) Heping Zhang et al.   JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION

An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits

(2010) Yi-Hsiang Hsu et al.   PLoS Genetics

Genome-wide Association and Replication Studies Identified TRHR as an Important Gene for Lean Body Mass

(2009) Xiao-Gang Liu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Univariate/Multivariate Genome-Wide Association Scans Using Data from Families and Unrelated Samples

(2009) Lei Zhang et al.   PLoS One

Powerful Bivariate Genome-Wide Association Analyses Suggest the SOX6 Gene Influencing Both Obesity and Osteoporosis Phenotypes in Males

(2009) Yao-Zhong Liu et al.   PLoS One

Family-Based Bivariate Association Tests for Quantitative Traits

(2009) Lei Zhang et al.   PLoS One

Common variants near MC4R are associated with fat mass, weight and risk of obesity

(2008) Ruth J F Loos et al.   NATURE GENETICS