Exit from germinal center to become quiescent memory B cells depends on metabolic reprograming and provision of a survival signal

Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis

(2020) Tom Sidwell et al.   Nature Communications

BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression

(2020) Francis M. Grant et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The transcription factor Hhex cooperates with the corepressor Tle3 to promote memory B cell development

(2020) Brian J. Laidlaw et al.   NATURE IMMUNOLOGY

Protein Amounts of the MYC Transcription Factor Determine Germinal Center B Cell Division Capacity

(2019) Shlomo Finkin et al.   IMMUNITY

T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate

(2018) Wataru Ise et al.   IMMUNITY

Generation of memory B cells and their reactivation

(2018) Takeshi Inoue et al.   IMMUNOLOGICAL REVIEWS

Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging

(2018) Isabelle Stewart et al.   IMMUNITY

Metabolic Regulation of the Immune Humoral Response

(2017) Mark Boothby et al.   IMMUNITY

CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity

(2017) Dan Suan et al.   IMMUNITY

Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase

(2017) Jonatan Ersching et al.   IMMUNITY

The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help

(2017) Takeshi Inoue et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Eph-related tyrosine kinase ligand Ephrin-B1 marks germinal center and memory precursor B cells

(2017) Brian J. Laidlaw et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ephrin B1–mediated repulsion and signaling control germinal center T cell territoriality and function

(2017) Peiwen Lu et al.   SCIENCE

The microanatomic segregation of selection by apoptosis in the germinal center

(2017) Christian T. Mayer et al.   SCIENCE

Regulated selection of germinal-center cells into the memory B cell compartment

(2016) Ryo Shinnakasu et al.   NATURE IMMUNOLOGY

Sequencing and cloning of antigen-specific antibodies from mouse memory B cells

(2016) Lotta von Boehmer et al.   Nature Protocols

A simple and efficient seamless DNA cloning method using SLiCE from Escherichia coli laboratory strains and its application to SLiP site-directed mutagenesis

(2015) Ken Motohashi   BMC BIOTECHNOLOGY

BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory

(2015) Timothy E. O’Sullivan et al.   IMMUNITY

The FOXO1 Transcription Factor Instructs the Germinal Center Dark Zone Program

(2015) David Dominguez-Sola et al.   IMMUNITY

PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones

(2015) Sandrine Sander et al.   IMMUNITY

CNOT3 contributes to early B cell development by controllingIghrearrangement andp53mRNA stability

(2015) Takeshi Inoue et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Memory B cells contribute to rapid Bcl6 expression by memory follicular helper T cells

(2014) W. Ise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A novel cell-cycle-indicator, mVenus-p27K−, identifies quiescent cells and visualizes G0–G1 transition

(2014) Toshihiko Oki et al.   Scientific Reports

A tool kit for rapid cloning and expression of recombinant antibodies

(2014) Tihomir S. Dodev et al.   Scientific Reports

Germinal Center Centroblasts Transition to a Centrocyte Phenotype According to a Timed Program and Depend on the Dark Zone for Effective Selection

(2013) Oliver Bannard et al.   IMMUNITY

Repression of the Transcription Factor Bach2 Contributes to Predisposition of IgG1 Memory B Cells toward Plasma Cell Differentiation

(2013) Kohei Kometani et al.   IMMUNITY

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry

(2012) David Dominguez-Sola et al.   NATURE IMMUNOLOGY

The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers

(2012) Dinis Pedro Calado et al.   NATURE IMMUNOLOGY

Bcl6 Protein Expression Shapes Pre-Germinal Center B Cell Dynamics and Follicular Helper T Cell Heterogeneity

(2011) Masahiro Kitano et al.   IMMUNITY

Memory B cells, but not long-lived plasma cells, possess antigen specificities for viral escape mutants

(2011) Whitney E. Purtha et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses

(2010) Michelle A. Linterman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PI3 Kinase Signals BCR-Dependent Mature B Cell Survival

(2009) Lakshmi Srinivasan et al.   CELL

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

(2009) M. Saito et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

(2008) X. Brochet et al.   NUCLEIC ACIDS RESEARCH