Circular RNA circ-CPA4/ let-7 miRNA/PD-L1 axis regulates cell growth, stemness, drug resistance and immune evasion in non-small cell lung cancer (NSCLC)

Tumor mutational load, CD8+ T cells, expression of PD-L1 and HLA class I to guide immunotherapy decisions in NSCLC patients

(2020) Daan P. Hurkmans et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti–PD-1 immunotherapy

(2020) Balamayoora Theivanthiran et al.   JOURNAL OF CLINICAL INVESTIGATION

LIN28/let-7/PD-L1 Pathway as a Target for Cancer Immunotherapy

(2019) Yanlian Chen et al.   Cancer Immunology Research

MiR-873/PD-L1 axis regulates the stemness of breast cancer cells

(2019) Lanlan Gao et al.   EBioMedicine

PD-1/PD-L1 blockade rescue exhausted CD8+ T cells in gastrointestinal stromal tumours via the PI3K/Akt/mTOR signalling pathway

(2019) Rui Zhao et al.   CELL PROLIFERATION

Circular RNA circ-FOXM1 facilitates cell progression as ceRNA to target PPDPF and MACC1 by sponging miR-1304-5p in non-small cell lung cancer

(2019) Guohua Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The circRNA circP4HB promotes NSCLC aggressiveness and metastasis by sponging miR-133a-5p

(2019) Tao Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Analysis of the PD-1/PD-L1 axis in human autoimmune thyroid disease: Insights into pathogenesis and clues to immunotherapy associated thyroid autoimmunity

(2019) Daniel Álvarez-Sierra et al.   JOURNAL OF AUTOIMMUNITY

Long noncoding RNA LINC00473 drives the progression of pancreatic cancer via upregulating programmed death-ligand 1 by sponging microRNA-195-5p

(2019) Wen-Yang Zhou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

TOX promotes the exhaustion of antitumor CD8+ T cells by preventing PD1 degradation in hepatocellular carcinoma

(2019) Xiaochen Wang et al.   JOURNAL OF HEPATOLOGY

MicroRNA-421 promotes proliferation and invasion of non-small cell lung cancer cells through targeting PDCD4

(2019) Ying-Nan Yang et al.   PATHOLOGY RESEARCH AND PRACTICE

MicroRNA let-7g acts as tumor suppressor and predictive biomarker for chemoresistance in human epithelial ovarian cancer

(2019) Flavia Biamonte et al.   Scientific Reports

let-7i inhibits proliferation and migration of bladder cancer cells by targeting HMGA1

(2019) M-M Qin et al.   BMC Urology

CircRNA Expression Pattern and ceRNA and miRNA–mRNA Networks Involved in Anther Development in the CMS Line of Brassica campestris

(2019) Yuwei Liang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

circCPA4 acts as a prognostic factor and regulates the proliferation and metastasis of glioma

(2019) Hao Peng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of the dynamic tumor microenvironment in controversies regarding immune checkpoint inhibitors for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations

(2019) Anqi Lin et al.   Molecular Cancer

Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer

(2019) Matthew D. Hellmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

CeRNA Expression Profiling Identifies KIT-Related circRNA-miRNA-mRNA Networks in Gastrointestinal Stromal Tumour

(2019) Ning Jia et al.   Frontiers in Genetics

Niclosamide, an antihelmintic drug, enhances efficacy of PD-1/PD-L1 immune checkpoint blockade in non-small cell lung cancer

(2019) Fan Luo et al.   Journal for ImmunoTherapy of Cancer

Blockade of PD-L1 Enhances Cancer Immunotherapy by Regulating Dendritic Cell Maturation and Macrophage Polarization

(2019) Nai-Yun Sun et al.   Cancers

Tumour Microenvironment and Immune Evasion in EGFR Addicted NSCLC: Hurdles and Possibilities

(2019) Antonio Santaniello et al.   Cancers

Dramatic Response of Leptomeningeal Carcinomatosis to Nivolumab in PD-L1 Highly Expressive Non-small Cell Lung Cancer: A Case Report

(2019) David Arias Ron et al.   Frontiers in Oncology

Programmed Death Ligand 1 Indicates Pre-Existing Adaptive Immune Response by Tumor-Infiltrating CD8+ T Cells in Non-Small Cell Lung Cancer

(2019) Yi-Ming Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Clinical significance of PD-L1 expression in serum-derived exosomes in NSCLC patients

(2019) Chuling Li et al.   Journal of Translational Medicine

miR-433 suppresses tumor progression via Smad2 in non-small cell lung cancer

(2019) Jianing Li et al.   PATHOLOGY RESEARCH AND PRACTICE

PIDD interaction with KEAP1 as a new mutation-independent mechanism to promote NRF2 stabilization and chemoresistance in NSCLC

(2019) Lili Ji et al.   Scientific Reports

Corrigendum to ‘MiR-873/PD-L1 axis regulates the stemness of breast cancer cells’ EBioMedicine 41 (2019) 395–407

(2019) Lanlan Gao et al.   EBioMedicine

Expression of programmed death ligand 1 (PD-L1) is associated with metastasis and differentiation in gastric cancer

(2019) Peng-xing He et al.   LIFE SCIENCES

PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC

(2018) Marzia Del Re et al.   BRITISH JOURNAL OF CANCER

PD-1 blockade in advanced NSCLC: A focus on pembrolizumab

(2018) Solange Peters et al.   CANCER TREATMENT REVIEWS

CD10 + GPR77 + Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness

(2018) Shicheng Su et al.   CELL

JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance

(2018) Tianyi Wang et al.   Cell Metabolism

Avelumab in non-small-cell lung cancer

(2018) Rafael Rosell et al.   LANCET ONCOLOGY

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

(2018) Gang Chen et al.   NATURE

Let-7 microRNA as a potential therapeutic target with implications for immunotherapy

(2018) Maud-Emmanuelle Gilles et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC

(2018) Xiaoyuan Wang et al.   Stem Cell Research & Therapy

Dendritic Cells and CD8 T Cell Immunity in Tumor Microenvironment

(2018) Chunmei Fu et al.   Frontiers in Immunology

PD-L1 on tumor cells is sufficient for immune evasion in immunogenic tumors and inhibits CD8 T cell cytotoxicity

(2017) Vikram R. Juneja et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer

(2017) Scott J. Antonia et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intratumoral CD8 + T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity

(2017) Brendan L. Horton et al.   Cancer Immunology Research

Atezolizumab for the treatment of non-small cell lung cancer

(2017) Fernando C. Santini et al.   Expert Review of Clinical Pharmacology

Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer

(2016) Martin Reck et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA let-7, T Cells, and Patient Survival in Colorectal Cancer

(2016) R. Dou et al.   Cancer Immunology Research

Over-expression of cofilin-1 suppressed growth and invasion of cancer cells is associated with up-regulation of let-7 microRNA

(2015) Cheng-Han Tsai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses

(2015) Jun Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA