Single‐cell RNA sequencing analysis of SARS‐CoV‐2 entry receptors in human organoids

In Vitro and In Vivo Development of the Human Airway at Single-Cell Resolution

(2020) Alyssa J. Miller et al.   DEVELOPMENTAL CELL

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

A Novel Coronavirus from Patients with Pneumonia in China, 2019

(2020) Na Zhu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Single-Cell Transcriptomic Comparison of Human Fetal Retina, hPSC-Derived Retinal Organoids, and Long-Term Retinal Cultures

(2020) Akshayalakshmi Sridhar et al.   Cell Reports

Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses

(2020) Furong Qi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Animal models of mechanisms of SARS‐CoV‐2 infection and COVID‐19 pathology

(2020) Simon J. Cleary et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

(2020) Vanessa Monteil et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

(2020) Wanbo Tai et al.   Cellular & Molecular Immunology

COVID-19 and Multiorgan Response

(2020) Sevim Zaim et al.   CURRENT PROBLEMS IN CARDIOLOGY

Comorbidities and multi-organ injuries in the treatment of COVID-19

(2020) Tianbing Wang et al.   LANCET

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

(2020) Linlin Bao et al.   NATURE

Drug researchers pursue new lines of attack against COVID-19

(2020) Charlotte Harrison   NATURE BIOTECHNOLOGY

COVID-19: organoids go viral

(2020) Hans Clevers   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SARS-CoV-2 productively infects human gut enterocytes

(2020) Mart M. Lamers et al.   SCIENCE

Developing Organoids from Ovarian Cancer as Experimental and Preclinical Models

(2020) Nina Maenhoudt et al.   Stem Cell Reports

D3Targets-2019-nCoV: a webserver for predicting drug targets and for multi-target and multi-site based virtual screening against COVID-19

(2020) Yulong Shi et al.   Acta Pharmaceutica Sinica B

TMPRSS2 and TMPRSS4 promote SARS-CoV-2 infection of human small intestinal enterocytes

(2020) Ruochen Zang et al.   Science Immunology

Cellular Nanosponges Inhibit SARS-CoV-2 Infectivity

(2020) Qiangzhe Zhang et al.   NANO LETTERS

COVID-19 Hyperinflammation: What about Neutrophils?

(2020) Athanasios Didangelos   mSphere

Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases

(2019) Ludovica Grassi et al.   Cell Death & Disease

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Individual brain organoids reproducibly form cell diversity of the human cerebral cortex

(2019) Silvia Velasco et al.   NATURE

Organoids – New Models for Host–Helminth Interactions

(2019) María A. Duque-Correa et al.   TRENDS IN PARASITOLOGY

Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models

(2018) Susan Tsai et al.   BMC CANCER

Organoids for Drug Discovery and Personalized Medicine

(2018) Toshio Takahashi   Annual Review of Pharmacology and Toxicology

Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics

(2018) Haojia Wu et al.   Cell Stem Cell

Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition

(2018) Masayuki Fujii et al.   Cell Stem Cell

Consequences of congenital Zika virus infection

(2017) Derek J Platt et al.   Current Opinion in Virology

Modeling Development and Disease with Organoids

(2016) Hans Clevers   CELL

Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth

(2016) Hengli Tang et al.   Cell Stem Cell

Replication of human noroviruses in stem cell-derived human enteroids

(2016) K. Ettayebi et al.   SCIENCE

Three-dimensional organotypic culture: experimental models of mammalian biology and disease

(2014) Eliah R. Shamir et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Organogenesis in a dish: Modeling development and disease using organoid technologies

(2014) M. A. Lancaster et al.   SCIENCE

Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy

(2014) T Grabinger et al.   Cell Death & Disease

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Engineering of three-dimensional microenvironments to promote contractile behavior in primary intestinal organoids

(2013) Rebecca L. DiMarco et al.   Integrative Biology

Cytosystems dynamics in self-organization of tissue architecture

(2013) Yoshiki Sasai   NATURE

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perfused multiwell plate for 3D liver tissue engineering

(2009) Karel Domansky et al.   LAB ON A CHIP

A new mouse-adapted strain of SARS-CoV as a lethal model for evaluating antiviral agents in vitro and in vivo

(2009) Craig W. Day et al.   VIROLOGY

Self-Organized Formation of Polarized Cortical Tissues from ESCs and Its Active Manipulation by Extrinsic Signals

(2008) Mototsugu Eiraku et al.   Cell Stem Cell