Mechanisms of RANKL delivery to the osteoclast precursor cell surface

The Role of Bone-Derived Exosomes in Regulating Skeletal Metabolism and Extraosseous Diseases

(2020) Huili Lyu et al.   Frontiers in Cell and Developmental Biology

Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

(2019) Laura M. Doyle et al.   Cells

MMP14 is a novel target of PTH signaling in osteocytes that controls resorption by regulating soluble RANKL production

(2018) Jesus Delgado-Calle et al.   FASEB JOURNAL

Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss

(2018) Jinhu Xiong et al.   Nature Communications

Coupling of bone resorption and formation by RANKL reverse signalling

(2018) Yuki Ikebuchi et al.   NATURE

The induction of RANKL molecule clustering could stimulate early osteoblast differentiation

(2018) Eri Sone et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel approaches for two and three dimensional multiplexed imaging of osteocytes

(2015) Suzan A. Kamel-ElSayed et al.   BONE

Osteoblast-derived microvesicles: A novel mechanism for communication between osteoblasts and osteoclasts

(2015) Lili Deng et al.   BONE

Matrix vesicles: Are they anchored exosomes?

(2015) Irving M. Shapiro et al.   BONE

Principles of antibody-mediated TNF receptor activation

(2015) H Wajant   CELL DEATH AND DIFFERENTIATION

The osteocyte plays multiple roles in bone remodeling and mineral homeostasis

(2015) Huayue Chen et al.   Medical Molecular Morphology

RANKL/OPG; Critical role in bone physiology

(2015) T. John Martin et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Biology of Bone Tissue: Structure, Function, and Factors That Influence Bone Cells

(2015) Rinaldo Florencio-Silva et al.   Biomed Research International

Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone

(2015) Jinhu Xiong et al.   PLoS One

Manipulation of receptor oligomerization as a strategy to inhibit signaling by TNF superfamily members

(2014) J. T. Warren et al.   Science Signaling

RANKL subcellular trafficking and regulatory mechanisms in osteocytes

(2013) Masashi Honma et al.   JOURNAL OF BONE AND MINERAL RESEARCH

RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor

(2012) Christopher A. Nelson et al.   STRUCTURE

Expression of RANKL/OPG during bone remodeling in vivo

(2011) H. Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF

(2011) Eleni Douni et al.   HUMAN MOLECULAR GENETICS

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Function of OPG as a traffic regulator for RANKL is crucial for controlled osteoclastogenesis

(2010) Shigeki Aoki et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Evaluation of Pharmaceuticals With a Novel 50-Hour Animal Model of Bone Loss*

(2009) Yoshiya Tomimori et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Vps33a Mediates RANKL Storage in Secretory Lysosomes in Osteoblastic Cells

(2009) Yoshiaki Kariya et al.   JOURNAL OF BONE AND MINERAL RESEARCH