Evidence Supporting the Safety of Pegylated Diethylaminoethyl-Chitosan Polymer as a Nanovector for Gene Therapy Applications

Chitosan Nanoparticles: Shedding Light on Immunotoxicity and Hemocompatibility

(2020) Sandra Jesus et al.   Frontiers in Bioengineering and Biotechnology

Chitosan-heparin nanoparticle coating on anodized NiTi for improvement of blood compatibility and biocompatibility

(2019) Fatemeh Mohammadi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis of CdS-modified chitosan quantum dots for the drug delivery of Sesamol

(2019) Hani Nasser Abdelhamid et al.   CARBOHYDRATE POLYMERS

Structural characterization and protective effect of gallic acid grafted O-carboxymethyl chitosan against hydrogen peroxide-induced oxidative damage

(2019) Ruyu Bai et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synergistic Toxicity Produced by Mixtures of Biocompatible Gold Nanoparticles and Widely Used Surfactants

(2018) Aurora L. Ginzburg et al.   ACS Nano

Chitosan nanoparticles’ functionality as redox active drugs through cytotoxicity, radical scavenging and cellular behaviour

(2018) Sreelatha Sarangapani et al.   Integrative Biology

Immunostimulatory effects of sulfated chitosans on RAW 264.7 mouse macrophages via the activation of PI3 K/Akt signaling pathway

(2018) Yue Yang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Diethylaminoethyl- chitosan as an efficient carrier for siRNA delivery: Improving the condensation process and the nanoparticles properties

(2018) Ricchard Hallan Felix Viegas de Souza et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Chitosan gold nanoparticles induce cell death in HeLa and MCF-7 cells through reactive oxygen species production

(2018) Ana Carolina Martínez-Torres et al.   International Journal of Nanomedicine

In vivo therapeutic efficacy of TNFα silencing by folate-PEG-chitosan-DEAE/siRNA nanoparticles in arthritic mice

(2018) Qin Shi et al.   International Journal of Nanomedicine

Mapping of the available standards against the regulatory needs for nanomedicines

(2018) Blanka Halamoda-Kenzaoui et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Biomedical Applications of Chitosan and Its Derivative Nanoparticles

(2018) Dongying Zhao et al.   Polymers

Chitosan enhances gene delivery of oligonucleotide complexes with magnetic nanoparticles–cell-penetrating peptide

(2018) Moataz Dowaidar et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Chitosan in Biomedical Engineering: A Critical Review

(2018) Shabnam Mohebbi et al.   Current Stem Cell Research & Therapy

Overview of the blood compatibility of nanomedicines: A trend analysis of in vitro and in vivo studies

(2018) Patricia Urbán et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Effects of Chitosan Oligosaccharides on Human Blood Components

(2018) Xi Guo et al.   Frontiers in Pharmacology

Chitosan as a bioactive polymer: Processing, properties and applications

(2017) A. Muxika et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Effects of tripolyphosphate on cellular uptake and RNA interference efficiency of chitosan-based nanoparticles in Raw 264.7 macrophages

(2017) Bo Xiao et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Nanoparticle–membrane interactions

(2017) Claudia Contini et al.   Journal of Experimental Nanoscience

Co-delivery of IL17RB siRNA and doxorubicin by chitosan-based nanoparticles for enhanced anticancer efficacy in breast cancer cells

(2016) Vahideh Alinejad et al.   BIOMEDICINE & PHARMACOTHERAPY

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

(2016) Elizabeth. C. Carroll et al.   IMMUNITY

Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

(2016) Daniel Bobo et al.   PHARMACEUTICAL RESEARCH

Biological effects of chitosan and its derivatives

(2015) Dai-Hung Ngo et al.   FOOD HYDROCOLLOIDS

Biocompatibility of a self-assembled glycol chitosan nanogel

(2015) Paula Pereira et al.   TOXICOLOGY IN VITRO

Strategies to improve chitosan hemocompatibility: A review

(2014) Vera Balan et al.   EUROPEAN POLYMER JOURNAL

Spectrum and Mechanisms of Inflammasome Activation by Chitosan

(2014) C. L. Bueter et al.   JOURNAL OF IMMUNOLOGY

Folate receptor-β constitutes a marker for human proinflammatory monocytes

(2014) Jiayin Shen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Folic acid conjugated chitosan for targeted delivery of siRNA to activated macrophages in vitro and in vivo

(2014) Chuanxu Yang et al.   Journal of Materials Chemistry B

Cell Membranes Open “Doors” for Cationic Nanoparticles/Biomolecules: Insights into Uptake Kinetics

(2013) Jiaqi Lin et al.   ACS Nano

Cytokines as biomarkers of nanoparticle immunotoxicity

(2013) Mahmoud Elsabahy et al.   CHEMICAL SOCIETY REVIEWS

Hematotoxicological analysis of surface-modified and -unmodified chitosan nanoparticles

(2013) Ragima Nadesh et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Understanding the correlation between in vitro and in vivo immunotoxicity tests for nanomedicines

(2013) Marina A. Dobrovolskaia et al.   JOURNAL OF CONTROLLED RELEASE

Synthesis and evaluation of diethylethylamine–chitosan for gene delivery: composition effects on thein vitrotransfection efficiency

(2013) Franciele de Paula Pansani Oliveira et al.   NANOTECHNOLOGY

Mechanisms of Nanoparticle-Induced Oxidative Stress and Toxicity

(2013) Amruta Manke et al.   Biomed Research International

Erythrocytes load of low molecular weight chitosan nanoparticles as a potential vascular drug delivery system

(2012) Wen Fan et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Low molecular weight chitosan conjugated with folate for siRNA delivery in vitro: optimization studies

(2012) Qin Shi et al.   International Journal of Nanomedicine

Development of lauroyl sulfated chitosan for enhancing hemocompatibility of chitosan

(2011) R. Shelma et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Functional Alteration of a Dimeric Insecticidal Lectin to a Monomeric Antifungal Protein Correlated to Its Oligomeric Status

(2011) Nilanjana Banerjee et al.   PLoS One

The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility

(2010) Biraja C. Dash et al.   BIOMATERIALS

Chitosan oligosaccharides protect mice from LPS challenge by attenuation of inflammation and oxidative stress

(2010) Ying Qiao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Toxicity Pathway Focused Gene Expression Profiling of PEI-Based Polymers for Pulmonary Applications

(2010) Andrea Beyerle et al.   MOLECULAR PHARMACEUTICS

Folate receptor targeting silica nanoparticle probe for two-photon fluorescence bioimaging

(2010) Xuhua Wang et al.   Biomedical Optics Express

Effect of biological matrix and sample preparation on qPCR quantitation of siRNA drugs in animal tissues

(2010) Jessica Seitzer et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Mannosylated chitosan-graft-polyethylenimine as a gene carrier for Raw 264.7 cell targeting

(2009) Hu-Lin Jiang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment

(2009) Marc T Abrams et al.   MOLECULAR THERAPY

Cytokine Signaling Modules in Inflammatory Responses

(2008) John J. O'Shea et al.   IMMUNITY

Preclinical Studies To Understand Nanoparticle Interaction with the Immune System and Its Potential Effects on Nanoparticle Biodistribution

(2008) Marina A. Dobrovolskaia et al.   MOLECULAR PHARMACEUTICS

Wide Varieties of Cationic Nanoparticles Induce Defects in Supported Lipid Bilayers

(2008) Pascale R. Leroueil et al.   NANO LETTERS