Roles of ABCC1 and ABCC4 in Proliferation and Migration of Breast Cancer Cell Lines

ABCC4 / MRP4 contributes to the aggressiveness of Myc‐associated epithelial ovarian cancer

(2020) Moonsun Jung et al.   INTERNATIONAL JOURNAL OF CANCER

Multidrug resistance protein 4 (MRP4/ABCC4) is overexpressed in clear cell renal cell carcinoma (ccRCC) and is essential to regulate cell proliferation

(2020) Juan Pablo Melana Colavita et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Identification of MRP4/ABCC4 as a Target for Reducing the Proliferation of Pancreatic Ductal Adenocarcinoma Cells by Modulating the cAMP Efflux

(2019) Alejandro Carozzo et al.   MOLECULAR PHARMACOLOGY

Breast cancer statistics, 2019

(2019) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer

(2018) Akimitsu Yamada et al.   MOLECULAR CANCER RESEARCH

Release of Platelet-Derived Sphingosine-1-Phosphate Involves Multidrug Resistance Protein 4 (MRP4/ABCC4) and Is Inhibited by Statins

(2018) Katja Vogt et al.   THROMBOSIS AND HAEMOSTASIS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Triple-Negative Breast Cancer: Current State of the Art

(2018) Francesca Rastelli et al.   TUMORI

Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis

(2016) Junko Tsuchida et al.   JOURNAL OF SURGICAL RESEARCH

Role of the Drug Transporter ABCC3 in Breast Cancer Chemoresistance

(2016) Sai A. Balaji et al.   PLoS One

Triple negative breast cancer development can be selectively suppressed by sustaining an elevated level of cellular cyclic AMP through simultaneously blocking its efflux and decomposition

(2016) Wei Wang et al.   Oncotarget

Multiple drug resistance-associated protein (MRP4) exports prostaglandin E2 (PGE2) and contributes to metastasis in basal/triple negative breast cancer

(2016) Tyler J. Kochel et al.   Oncotarget

Predictive markers in elderly patients with estrogen receptor-positive breast cancer treated with aromatase inhibitors: an array-based pharmacogenetic study

(2015) E Rumiato et al.   PHARMACOGENOMICS JOURNAL

Inhibition of multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme

(2015) Amanda Tivnan et al.   Frontiers in Neuroscience

Multidrug resistance protein 4/ ATP binding cassette transporter 4: a new potential therapeutic target for acute myeloid leukemia

(2015) Sabrina Copsel et al.   Oncotarget

High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4)

(2014) Leanna Cheung et al.   BIOCHEMICAL PHARMACOLOGY

Multidrug Resistance Protein 1 (MRP1, ABCC1), a “Multitasking” ATP-binding Cassette (ABC) Transporter

(2014) Susan P. C. Cole   JOURNAL OF BIOLOGICAL CHEMISTRY

ABCC4 is required for cell proliferation and tumorigenesis in non-small cell lung cancer

(2014) Wentao Yue et al.   OncoTargets and Therapy

High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival

(2013) Akimitsu Yamada et al.   BREAST CANCER RESEARCH AND TREATMENT

The expression profile of ATP-binding cassette transporter genes in breast carcinoma

(2013) Viktor Hlaváč et al.   PHARMACOGENOMICS

Mechanism of RPE Cell Death in α-Crystallin Deficient Mice: A Novel and Critical Role for MRP1-Mediated GSH Efflux

(2012) Parameswaran G. Sreekumar et al.   PLoS One

ATP-binding cassette ABCC1 is involved in the release of sphingosine 1-phosphate from rat uterine leiomyoma ELT3 cells and late pregnant rat myometrium

(2011) Zahra Tanfin et al.   CELLULAR SIGNALLING

Mammalian multidrug-resistance proteins (MRPs)

(2011) Andrew J. Slot et al.   Essays in Biochemistry

Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes

(2011) Yassine Sassi et al.   FASEB JOURNAL

The ABCC4 gene is a promising target for pancreatic cancer therapy

(2011) Zhuo Zhang et al.   GENE

Multidrug Resistance Protein 4 (MRP4/ABCC4) Regulates cAMP Cellular Levels and Controls Human Leukemia Cell Proliferation and Differentiation

(2011) Sabrina Copsel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ABCC Multidrug Transporters in Childhood Neuroblastoma: Clinical and Biological Effects Independent of Cytotoxic Drug Efflux

(2011) Michelle J. Henderson et al.   JNCI-Journal of the National Cancer Institute

Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells

(2010) Silvio Naviglio et al.   CANCER BIOLOGY & THERAPY

Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2

(2010) Kazuaki Takabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The putative cannabinoid receptor GPR55 defines a novel autocrine loop in cancer cell proliferation

(2010) R Piñeiro et al.   ONCOGENE

Small-Molecule Multidrug Resistance-Associated Protein 1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Models of Neuroblastoma

(2009) C. A. Burkhart et al.   CANCER RESEARCH

Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules

(2008) F RUSSEL et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

ABC multidrug transporters: structure, function and role in chemoresistance

(2007) Frances J Sharom   PHARMACOGENOMICS