Mast cells and angiogenesis in multiple sclerosis

Calming Down Mast Cells with Ketotifen: A Potential Strategy for Multiple Sclerosis Therapy?

(2019) Karen Henriette Pinke et al.   Neurotherapeutics

Natalizumab reduces serum pro-angiogenic activity in MS patients

(2018) Pietro Iaffaldano et al.   NEUROLOGICAL SCIENCES

Mast Cells and Innate Lymphoid Cells: Underappreciated Players in CNS Autoimmune Demyelinating Disease

(2018) Melissa A. Brown et al.   Frontiers in Immunology

High frequency of intestinal T H 17 cells correlates with microbiota alterations and disease activity in multiple sclerosis

(2017) Ilaria Cosorich et al.   Science Advances

Sphingosine-1-phosphate and other lipid mediators generated by mast cells as critical players in allergy and mast cell function

(2016) Joseph M. Kulinski et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Meningeal mast cell-T cell crosstalk regulates T cell encephalitogenicity

(2016) Abigail E. Russi et al.   JOURNAL OF AUTOIMMUNITY

Lesion remyelinating activity of GSK239512 versus placebo in patients with relapsing-remitting multiple sclerosis: a randomised, single-blind, phase II study

(2016) Caryl J. Schwartzbach et al.   JOURNAL OF NEUROLOGY

Immunology of Multiple Sclerosis

(2016) Mireia Sospedra et al.   SEMINARS IN NEUROLOGY

The meninges: new therapeutic targets for multiple sclerosis

(2015) Abigail E. Russi et al.   Translational Research

Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia

(2015) Sabine Cerny-Reiterer et al.   Oncotarget

Sphingolipids: Important Players in Multiple Sclerosis

(2014) Ramona Halmer et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Angiogenesis in multiple sclerosis and experimental autoimmune encephalomyelitis

(2014) Francesco Girolamo et al.   Acta Neuropathologica Communications

The improvement of cognitive functions is associated with a decrease of plasma Osteopontin levels in Natalizumab treated relapsing multiple sclerosis

(2013) Pietro Iaffaldano et al.   BRAIN BEHAVIOR AND IMMUNITY

Vascular Endothelial Growth Factor–Induced Osteopontin Expression Mediates Vascular Inflammation and Neointima Formation via Flt-1 in Adventitial Fibroblasts

(2012) Xiao-Dong Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE

(2012) Alison L. Christy et al.   JOURNAL OF AUTOIMMUNITY

Bevacizumab Diminishes Experimental Autoimmune Encephalomyelitis by Inhibiting Spinal Cord Angiogenesis and Reducing Peripheral T-Cell Responses

(2012) Carolyn J. MacMillan et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mast Cells are Important Modifiers of Autoimmune Disease: With so Much Evidence, Why is There Still Controversy?

(2012) Melissa A. Brown et al.   Frontiers in Immunology

Mast cells promote Th1 and Th17 responses by modulating dendritic cell maturation and function

(2011) Anne Dudeck et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cre-Mediated Cell Ablation Contests Mast Cell Contribution in Models of Antibody- and T Cell-Mediated Autoimmunity

(2011) Thorsten B. Feyerabend et al.   IMMUNITY

Tryptase and chymase are angiogenic in vivo in the chorioallantoic membrane assay

(2011) Domenico Ribatti et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Tyrosine Kinase Inhibitors Ameliorate Autoimmune Encephalomyelitis in a Mouse Model of Multiple Sclerosis

(2011) Oliver Crespo et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Regulatory T Cells Enhance Mast Cell Production of IL-6 via Surface-Bound TGF- 

(2011) K. Ganeshan et al.   JOURNAL OF IMMUNOLOGY

Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient KitW-sh/W-sh mice

(2011) Silvia Piconese et al.   LABORATORY INVESTIGATION

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF

(2011) Mohamed El-Behi et al.   NATURE IMMUNOLOGY

The Expression of VEGF-A Is Down Regulated in Peripheral Blood Mononuclear Cells of Patients with Secondary Progressive Multiple Sclerosis

(2011) Ellen Iacobaeus et al.   PLoS One

Disruption of central nervous system barriers in multiple sclerosis

(2010) Jorge Ivan Alvarez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Signaling Pathways in the Activation of Mast Cells Cocultured with Astrocytes and Colocalization of Both Cells in Experimental Allergic Encephalomyelitis

(2010) D. Y. Kim et al.   JOURNAL OF IMMUNOLOGY

Meningeal Mast Cells Affect Early T Cell Central Nervous System Infiltration and Blood-Brain Barrier Integrity through TNF: A Role for Neutrophil Recruitment?

(2010) B. A. Sayed et al.   JOURNAL OF IMMUNOLOGY

Osteopontin concentrations are increased in cerebrospinal fluid during attacks of multiple sclerosis

(2010) Lars Börnsen et al.   Multiple Sclerosis Journal

A Placebo-Controlled Trial of Oral Cladribine for Relapsing Multiple Sclerosis

(2010) Gavin Giovannoni et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pathological Expression of CXCL12 at the Blood-Brain Barrier Correlates with Severity of Multiple Sclerosis

(2008) Erin E. McCandless et al.   AMERICAN JOURNAL OF PATHOLOGY

The Master Switch: The Role of Mast Cells in Autoimmunity and Tolerance

(2008) Blayne A. Sayed et al.   Annual Review of Immunology

Luteolin inhibits myelin basic protein-induced human mast cell activation and mast cell-dependent stimulation of Jurkat T cells

(2008) D Kempuraj et al.   BRITISH JOURNAL OF PHARMACOLOGY

Osteopontin Promotes Vascular Endothelial Growth Factor Dependent Breast Tumor Growth and Angiogenesis via Autocrine and Paracrine Mechanisms

(2008) G. Chakraborty et al.   CANCER RESEARCH

Mast cell transcripts are increased within and outside multiple sclerosis lesions

(2008) Nicolas Couturier et al.   JOURNAL OF NEUROIMMUNOLOGY