Evaluation of the Immunogenicity and Protective Efficacy of an Enterotoxigenic Escherichia coli CFA/I Adhesin–Heat-Labile Toxin Chimera

Biochemical and immunological characterization of an ETEC CFA/I adhesin cholera toxin B subunit chimera

(2020) Michael G. Jobling et al.   PLoS One

The TLR4 agonist adjuvant SLA-SE promotes functional mucosal antibodies against a parenterally delivered ETEC vaccine

(2019) Hong Liang et al.   npj Vaccines

Intradermal or sublingual delivery and heat-labile enterotoxin (LT) proteins shape immunologic outcomes to CFA/I fimbriae-derived subunit antigen vaccine against enterotoxigenic E. coli

(2019) Milton Maciel et al.   INFECTION AND IMMUNITY

Evaluation of transcutaneous immunization as a delivery route for an enterotoxigenic E. coli adhesin-based vaccine with CfaE, the colonization factor antigen 1 (CFA/I) tip adhesin

(2019) Julianne E. Rollenhagen et al.   VACCINE

Evaluation of the reactogenicity, adjuvanticity and antigenicity of LT(R192G) and LT(R192G/L211A) by intradermal immunization in mice

(2019) Milton Maciel et al.   PLoS One

Global disability-adjusted life-year estimates of long-term health burden and undernutrition attributable to diarrhoeal diseases in children younger than 5 years

(2018) Christopher Troeger et al.   Lancet Global Health

The Mucosal Vaccine Adjuvant LT(R192G/L211A) or dmLT

(2018) John D. Clements et al.   mSphere

Establishment, validation and application of a New World Primate model of ETEC disease for vaccine development

(2018) Julianne E. Rollenhagen et al.   INFECTION AND IMMUNITY

Prophylactic Efficacy of Hyperimmune Bovine Colostral Antiadhesin Antibodies Against Enterotoxigenic Escherichia coli Diarrhea: A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial

(2017) Stephen J. Savarino et al.   JOURNAL OF INFECTIOUS DISEASES

Characterization of guinea pig T cell responses elicited after EP-assisted delivery of DNA vaccines to the skin

(2017) Katherine Schultheis et al.   VACCINE

Considerations for using ETEC and Shigella disease burden estimates to guide vaccine development strategy

(2017) Divya Hosangadi et al.   VACCINE

Immunogenicity of a prototype enterotoxigenic Escherichia coli adhesin vaccine in mice and nonhuman primates

(2016) Stephanie A. Sincock et al.   VACCINE

Maternal Vaccination with a Fimbrial Tip Adhesin and Passive Protection of Neonatal Mice against Lethal Human Enterotoxigenic Escherichia coli Challenge

(2015) Wilson B. Luiz et al.   INFECTION AND IMMUNITY

Diarrhea Burden Due to Natural Infection with Enterotoxigenic Escherichia coli in a Birth Cohort in a Rural Egyptian Community

(2014) A. Mansour et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Immunizing Adult Female Mice with a TcpA-A2-CTB Chimera Provides a High Level of Protection for Their Pups in the Infant Mouse Model of Cholera

(2014) Gregory A. Price et al.   PLoS Neglected Tropical Diseases

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Efficacy and safety of a patch vaccine containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase 3, randomised, double-blind, placebo-controlled field trial in travellers from Europe to Mexico and Guatemala

(2013) Ronald H Behrens et al.   LANCET INFECTIOUS DISEASES

Moving beyond a heat-labile enterotoxin-based vaccine against enterotoxigenic Escherichia coli

(2013) Mark S Riddle et al.   LANCET INFECTIOUS DISEASES

Evaluation of TcpF-A2-CTB Chimera and Evidence of Additive Protective Efficacy of Immunizing with TcpF and CTB in the Suckling Mouse Model of Cholera

(2012) Gregory A. Price et al.   PLoS One

Estimating the Contribution of Acute Gastroenteritis to the Overall Prevalence of Irritable Bowel Syndrome

(2012) Eric D Shah et al.   Journal of Neurogastroenterology and Motility

Transcutaneous and intradermal vaccination

(2011) Behazine Combadiere et al.   Human vaccines & immunotherapeutics

A systematic review of ETEC epidemiology focusing on colonization factor and toxin expression

(2011) S.D. Isidean et al.   VACCINE

Toxin-Mediated Effects on the Innate Mucosal Defenses: Implications for Enteric Vaccines

(2009) G. M. Glenn et al.   INFECTION AND IMMUNITY

What Role Does the Route of Immunization Play in the Generation of Protective Immunity against Mucosal Pathogens?

(2009) I. M. Belyakov et al.   JOURNAL OF IMMUNOLOGY

Transient Facial Nerve Paralysis (Bell's Palsy) following Intranasal Delivery of a Genetically Detoxified Mutant of Escherichia coli Heat Labile Toxin

(2009) David J. M. Lewis et al.   PLoS One