Small RNAs derived from tRNAs and rRNAs are highly enriched in exosomes from both old and new world Leishmania providing evidence for conserved exosomal RNA Packaging

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Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets

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Biogenesis and secretion of exosomes

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A particular set of small non-coding RNAs is bound to the distinctive Argonaute protein of Trypanosoma cruzi: Insights from RNA-interference deficient organisms

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Surface analysis of Dicrocoelium dendriticum. The molecular characterization of exosomes reveals the presence of miRNAs

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Characterization of the small RNA content of Trypanosoma cruzi extracellular vesicles

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Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

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Massively Parallel Sequencing of Human Urinary Exosome/Microvesicle RNA Reveals a Predominance of Non-Coding RNA

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Absence of Metalloprotease GP63 Alters the Protein Content of Leishmania Exosomes

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Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity

(2014) Amy H. Buck et al.   Nature Communications

Gene Expression Changes Induced byTrypanosoma cruziShed Microvesicles in Mammalian Host Cells: Relevance of tRNA-Derived Halves

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tRNAs as regulators of biological processes

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Characterization of human plasma-derived exosomal RNAs by deep sequencing

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Leishmania donovani Targets Dicer1 to Downregulate miR-122, Lower Serum Cholesterol, and Facilitate Murine Liver Infection

(2013) June Ghosh et al.   Cell Host & Microbe

Malaria-Infected Erythrocyte-Derived Microvesicles Mediate Cellular Communication within the Parasite Population and with the Host Immune System

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Evidence of tRNA cleavage in apicomplexan parasites: Half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei

(2013) Roberto Galizi et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Extracellular vesicles shed by Trypanosoma cruzi are linked to small RNA pathways, life cycle regulation, and susceptibility to infection of mammalian cells

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tRNA-derived microRNA modulates proliferation and the DNA damage response and is down-regulated in B cell lymphoma

(2013) Roy L. Maute et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small RNAs derived from the 5′ end of tRNA can inhibit protein translation in human cells

(2013) Andrew Sobala et al.   RNA Biology

Slicing tRNAs to boost functional ncRNA diversity

(2013) Jennifer Gebetsberger et al.   RNA Biology

Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways

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Trichomonas vaginalis Exosomes Deliver Cargo to Host Cells and Mediate Host∶Parasite Interactions

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The Complete Exosome Workflow Solution: From Isolation to Characterization of RNA Cargo

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Genome-wide analysis of 3′-untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes

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Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing

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Processing of snoRNAs as a new source of regulatory non-coding RNAs

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Proteomic Analysis of Trypanosoma cruzi Secretome: Characterization of Two Populations of Extracellular Vesicles and Soluble Proteins

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Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi

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The structure and repertoire of small interfering RNAs inLeishmania (Viannia) braziliensisreveal diversification in the trypanosomatid RNAi pathway

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Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs

(2012) Zhihua Li et al.   NUCLEIC ACIDS RESEARCH

Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

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Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions

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Novel Features of a PIWI-Like Protein Homolog in the Parasitic Protozoan Leishmania

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tRNA-Derived Fragments Target the Ribosome and Function as Regulatory Non-Coding RNA inHaloferax volcanii

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Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice

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Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation

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In situ hybridisation for the detection of Leishmania species in paraffin wax-embedded canine tissues using a digoxigenin-labelled oligonucleotide probe

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Cloning, characterization and subcellular localization of a Trypanosoma cruzi argonaute protein defining a new subfamily distinctive of trypanosomatids

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An exosome-based secretion pathway is responsible for protein export from Leishmania and communication with macrophages

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Leishmania Exosomes Modulate Innate and Adaptive Immune Responses through Effects on Monocytes and Dendritic Cells

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A population of tRNA-derived small RNAs is actively produced in Trypanosoma cruzi and recruited to specific cytoplasmic granules

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Complete set of mitochondrial pan-edited mRNAs in Leishmania mexicana amazonensis LV78

(2010) Dmitri A. Maslov   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Evidence of RNA editing in Leishmania braziliensis promastigotes

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Functional delivery of viral miRNAs via exosomes

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Proteomic analysis identifies highly antigenic proteins in exosomes from M. tuberculosis-infected and culture filtrate protein-treated macrophages

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Human tRNA-derived small RNAs in the global regulation of RNA silencing

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Retention and Loss of RNA Interference Pathways in Trypanosomatid Protozoans

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Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

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Sec6-dependent sorting of fungal extracellular exosomes and laccase ofCryptococcus neoformans

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The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs

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Exosomes from human saliva as a source of microRNA biomarkers

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Differential Trypanosome Surface Coat Regulation by a CCCH Protein That Co-Associates with procyclin mRNA cis-Elements

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A Human snoRNA with MicroRNA-Like Functions

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GtRNAdb: a database of transfer RNA genes detected in genomic sequence

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Proteomic analysis of the secretome of Leishmania donovani

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