CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

(2020) Lorenzo Galluzzi et al.   Journal for ImmunoTherapy of Cancer

The molecular machinery of regulated cell death

(2019) Daolin Tang et al.   CELL RESEARCH

Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity

(2019) Lindsay DeVorkin et al.   Cell Reports

JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice

(2018) Xinxin Song et al.   GASTROENTEROLOGY

Dinaciclib induces immunogenic cell death and enhances anti-PD1–mediated tumor suppression

(2018) Dewan Md Sakib Hossain et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer immunotherapy using checkpoint blockade

(2018) Antoni Ribas et al.   SCIENCE

Pancreatic Ductal Adenocarcinoma: A Strong Imbalance of Good and Bad Immunological Cops in the Tumor Microenvironment

(2018) Etienne D. Foucher et al.   Frontiers in Immunology

TFAM is a novel mediator of immunogenic cancer cell death

(2018) Minghua Yang et al.   OncoImmunology

Inhibition of Aurora Kinase A Induces Necroptosis in Pancreatic Carcinoma

(2017) Yangchun Xie et al.   GASTROENTEROLOGY

Cyclin D–CDK4 kinase destabilizes PD-L1 via cullin 3–SPOP to control cancer immune surveillance

(2017) Jinfang Zhang et al.   NATURE

KRAS: The Critical Driver and Therapeutic Target for Pancreatic Cancer

(2017) Andrew M. Waters et al.   Cold Spring Harbor Perspectives in Medicine

Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity

(2016) R. D. Dorand et al.   SCIENCE

Immune Checkpoint Blockade: A Common Denominator Approach to Cancer Therapy

(2015) Suzanne L. Topalian et al.   CANCER CELL

Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma

(2015) R. Winograd et al.   Cancer Immunology Research

CDK-Mediated Regulation of Cell Functions via c-Jun Phosphorylation and AP-1 Activation

(2011) Tony J. Vanden Bush et al.   PLoS One

Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases

(2010) Kamil Paruch et al.   ACS Medicinal Chemistry Letters