Adapt or Perish: Evolutionary Rescue in a Gradually Deteriorating Environment

Tuning environmental timescales to evolve and maintain generalists

(2020) Vedant Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resist or perish: Fate of a microbial population subjected to a periodic presence of antimicrobial

(2020) Loïc Marrec et al.   PLoS Computational Biology

Theoretical investigation of stochastic clearance of bacteria: first-passage analysis

(2019) Hamid Teimouri et al.   Journal of the Royal Society Interface

Surfing on the seascape: Adaptation in a changing environment

(2019) Barbora Trubenová et al.   EVOLUTION

Evolving generalists in switching rugged landscapes

(2019) Shenshen Wang et al.   PLoS Computational Biology

Elucidating the correlations between cancer initiation times and lifetime cancer risks

(2019) Hamid Teimouri et al.   Scientific Reports

Evolutionary Rescue over a Fitness Landscape

(2018) Yoann Anciaux et al.   GENETICS

Stability of two-species communities: Drift, environmental stochasticity, storage effect and selection

(2018) Matan Danino et al.   THEORETICAL POPULATION BIOLOGY

Establishment in a new habitat by polygenic adaptation

(2018) N.H. Barton et al.   THEORETICAL POPULATION BIOLOGY

Noise-induced stabilization and fixation in fluctuating environment

(2018) Immanuel Meyer et al.   Scientific Reports

Antibiotic-induced population fluctuations and stochastic clearance of bacteria

(2018) Jessica Coates et al.   eLife

Evolutionary Rescue over a Fitness Landscape

(2018) Yoann Anciaux et al.   GENETICS

Quantifying the impact of a periodic presence of antimicrobial on resistance evolution in a homogeneous microbial population of fixed size

(2018) Loïc Marrec et al.   JOURNAL OF THEORETICAL BIOLOGY

Evolution of a Fluctuating Population in a Randomly Switching Environment

(2017) Karl Wienand et al.   PHYSICAL REVIEW LETTERS

Antibiotic tolerance facilitates the evolution of resistance

(2017) Irit Levin-Reisman et al.   SCIENCE

Climates Past, Present, and Yet-to-Come Shape Climate Change Vulnerabilities

(2017) Christopher P. Nadeau et al.   TRENDS IN ECOLOGY & EVOLUTION

Complex Interplay of Physiology and Selection in the Emergence of Antibiotic Resistance

(2016) Wei-Hsiang Lin et al.   CURRENT BIOLOGY

Evolutionary Phase Transitions in Random Environments

(2016) Antun Skanata et al.   PHYSICAL REVIEW LETTERS

Spatiotemporal microbial evolution on antibiotic landscapes

(2016) M. Baym et al.   SCIENCE

Simulation of biochemical reactions with time-dependent rates by the rejection-based algorithm

(2015) Vo Hong Thanh et al.   JOURNAL OF CHEMICAL PHYSICS

Tipping the mutation–selection balance: Limited migration increases the frequency of deleterious mutants

(2015) Jacob D. Cooper et al.   JOURNAL OF THEORETICAL BIOLOGY

Fate of a mutation in a fluctuating environment

(2015) Ivana Cvijović et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stochastic game dynamics under demographic fluctuations

(2015) Weini Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A tortoise–hare pattern seen in adapting structured and unstructured populations suggests a rugged fitness landscape in bacteria

(2015) Joshua R. Nahum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Impact of Environmental Fluctuations on Evolutionary Fitness Functions

(2015) Anna Melbinger et al.   Scientific Reports

Analysis of Bottlenecks in Experimental Models of Infection

(2015) Sören Abel et al.   PLoS Pathogens

FISHER'S GEOMETRIC MODEL WITH A MOVING OPTIMUM

(2014) Sebastian Matuszewski et al.   EVOLUTION

Evolutionary rescue: linking theory for conservation and medicine

(2014) Helen K. Alexander et al.   Evolutionary Applications

Evolutionary tipping points in the capacity to adapt to environmental change

(2014) Carlos A. Botero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The path of least resistance: aggressive or moderate treatment?

(2014) R. D. Kouyos et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Evolutionary rescue in a changing world

(2014) Stephanie M. Carlson et al.   TRENDS IN ECOLOGY & EVOLUTION

Quantifying the Role of Population Subdivision in Evolution on Rugged Fitness Landscapes

(2014) Anne-Florence Bitbol et al.   PLoS Computational Biology

Evolutionary Rescue in Structured Populations

(2013) Hildegard Uecker et al.   AMERICAN NATURALIST

Quantitative analyses of empirical fitness landscapes

(2013) Ivan G Szendro et al.   JOURNAL OF STATISTICAL MECHANICS-THEORY AND EXPERIMENT

Dynamics of evolutionary rescue in changing environments and the emergence of antibiotic resistance

(2013) Yue Wu et al.   JOURNAL OF THEORETICAL BIOLOGY

Evolutionary rescue from extinction is contingent on a lower rate of environmental change

(2013) Haley A. Lindsey et al.   NATURE

Establishment of New Mutations in Changing Environments

(2012) Stephan Peischl et al.   GENETICS

The impact of global climate change on genetic diversity within populations and species

(2012) Steffen U. Pauls et al.   MOLECULAR ECOLOGY

The probability of evolutionary rescue: towards a quantitative comparison between theory and evolution experiments

(2012) G. Martin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Evolutionary rescue: an emerging focus at the intersection between ecology and evolution

(2012) A. Gonzalez et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mutational Pathway Determines Whether Drug Gradients Accelerate Evolution of Drug-Resistant Cells

(2012) Philip Greulich et al.   PHYSICAL REVIEW LETTERS

On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient

(2012) R. Hermsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pre-existence and emergence of drug resistance in a generalized model of intra-host viral dynamics

(2012) Helen K. Alexander et al.   Epidemics

A Unified Treatment of the Probability of Fixation when Population Size and the Strength of Selection Change Over Time

(2011) D. Waxman   GENETICS

On the Fixation Process of a Beneficial Mutation in a Variable Environment

(2011) Hildegard Uecker et al.   GENETICS

The Value of Information for Populations in Varying Environments

(2011) Olivier Rivoire et al.   JOURNAL OF STATISTICAL PHYSICS

Acceleration of Emergence of Bacterial Antibiotic Resistance in Connected Microenvironments

(2011) Q. Zhang et al.   SCIENCE

Selection of Resistant Bacteria at Very Low Antibiotic Concentrations

(2011) Erik Gullberg et al.   PLoS Pathogens

Evolutionary Game Theory in Growing Populations

(2010) Anna Melbinger et al.   PHYSICAL REVIEW LETTERS

Stochastic models of population extinction

(2010) Otso Ovaskainen et al.   TRENDS IN ECOLOGY & EVOLUTION

Adaptation, Plasticity, and Extinction in a Changing Environment: Towards a Predictive Theory

(2010) Luis-Miguel Chevin et al.   PLOS BIOLOGY

Demographic and Genetic Constraints on Evolution

(2009) Richard Gomulkiewicz et al.   AMERICAN NATURALIST

Evolutionary rescue can prevent extinction following environmental change

(2009) Graham Bell et al.   ECOLOGY LETTERS

The Genetic Basis of Phenotypic Adaptation I: Fixation of Beneficial Mutations in the Moving Optimum Model

(2009) M. Kopp et al.   GENETICS

The Genetic Basis of Phenotypic Adaptation II: The Distribution of Adaptive Substitutions in the Moving Optimum Model

(2009) Michael Kopp et al.   GENETICS

The rate at which asexual populations cross fitness valleys

(2009) Daniel B. Weissman et al.   THEORETICAL POPULATION BIOLOGY

Population Extinction and the Genetics of Adaptation

(2008) H. Allen Orr et al.   AMERICAN NATURALIST

The fixation probability of beneficial mutations

(2008) Z Patwa et al.   Journal of the Royal Society Interface

Molecular Evolution under Fitness Fluctuations

(2008) Ville Mustonen et al.   PHYSICAL REVIEW LETTERS