A 12‐lipoxygenase‐Gpr31 signaling axis is required for pancreatic organogenesis in the zebrafish

Platelet-type 12-lipoxygenase deletion provokes a compensatory 12/15-lipoxygenase increase that exacerbates oxidative stress in islet β-cells

(2019) Abass M. Conteh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of the 12/15 lipoxygenase pathway accompanies metabolic decline in db/db pre-diabetic mice

(2018) Anca D. Dobrian et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase

(2018) Ansari Mukhtar Aleem et al.   BIOCHEMISTRY

The G protein–coupled receptor GPR31 promotes membrane association of KRAS

(2017) Nicole Fehrenbacher et al.   JOURNAL OF CELL BIOLOGY

An ALOX12–12-HETE–GPR31 signaling axis is a key mediator of hepatic ischemia–reperfusion injury

(2017) Xiao-Jing Zhang et al.   NATURE MEDICINE

An insulin signaling feedback loop regulates pancreas progenitor cell differentiation during islet development and regeneration

(2016) Lihua Ye et al.   DEVELOPMENTAL BIOLOGY

12-HETER1/GPR31, a high-affinity 12(S)-hydroxyeicosatetraenoic acid receptor, is significantly up-regulated in prostate cancer and plays a critical role in prostate cancer progression

(2016) Kenneth V. Honn et al.   FASEB JOURNAL

Mammalian lipoxygenases and their biological relevance

(2015) Hartmut Kuhn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Expression Pattern of 12-Lipoxygenase in Human Islets With Type 1 Diabetes and Type 2 Diabetes

(2015) Wojciech J. Grzesik et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Impact of Maternal n-3 Polyunsaturated Fatty Acid Deficiency on Dendritic Arbor Morphology and Connectivity of DevelopingXenopus laevisCentral NeuronsIn Vivo

(2015) Miki Igarashi et al.   JOURNAL OF NEUROSCIENCE

Polyamine biosynthesis is critical for growth and differentiation of the pancreas

(2015) Teresa L. Mastracci et al.   Scientific Reports

Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction

(2014) David A. Taylor-Fishwick et al.   DIABETOLOGIA

12-Lipoxygenase Promotes Obesity-Induced Oxidative Stress in Pancreatic Islets

(2014) S. A. Tersey et al.   MOLECULAR AND CELLULAR BIOLOGY

Lysophospholipid acyltransferases and eicosanoid biosynthesis in zebrafish myeloid cells

(2014) Simona Zarini et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Novel liquid chromatography–mass spectrometry method shows that vitamin E deficiency depletes arachidonic and docosahexaenoic acids in zebrafish (Danio rerio) embryos

(2013) Katie M. Lebold et al.   Redox Biology

Adipose Tissue-Specific Deletion of 12/15-Lipoxygenase Protects Mice from the Consequences of a High-Fat Diet

(2012) Banumathi K. Cole et al.   MEDIATORS OF INFLAMMATION

Suppression of Ptf1a Activity Induces Acinar-to-Endocrine Conversion

(2011) Daniel Hesselson et al.   CURRENT BIOLOGY

Stereocontrol of Arachidonic Acid Oxygenation by Vertebrate Lipoxygenases

(2011) Christian Jansen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of the Orphan G Protein-coupled Receptor GPR31 as a Receptor for 12-(S)-Hydroxyeicosatetraenoic Acid

(2011) Yande Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of Potent and Selective Inhibitors of Human Platelet-Type 12- Lipoxygenase

(2011) Victor Kenyon et al.   JOURNAL OF MEDICINAL CHEMISTRY

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Targeted knock-down of a structurally atypical zebrafish 12S-lipoxygenase leads to severe impairment of embryonic development

(2011) U. Haas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct populations of quiescent and proliferative pancreatic  -cells identified by HOTcre mediated labeling

(2009) D. Hesselson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment

(2008) Amy T McCurley et al.   BMC MOLECULAR BIOLOGY

Dietary omega 3 fatty acids and the developing brain

(2008) Sheila M. Innis   BRAIN RESEARCH

Multiple roles for Med12 in vertebrate endoderm development

(2008) Chong Hyun Shin et al.   DEVELOPMENTAL BIOLOGY

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols

Simultaneous lipidomic analysis of three families of bioactive lipid mediators leukotrienes, resolvins, protectins and related hydroxy-fatty acids by liquid chromatography/electrospray ionisation tandem mass spectrometry

(2007) Mojgan Masoodi et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY