Stat2 stability regulation: an intersection between immunity and carcinogenesis

Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma

(2019) Danielle Harmer et al.   Frontiers in Endocrinology

FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation

(2019) Cheol-Jung Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JAK-STAT Signaling: A Double-Edged Sword of Immune Regulation and Cancer Progression

(2019) Katie L. Owen et al.   Cancers

IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression

(2018) Jing Nan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current prospects of type II interferon γ signaling and autoimmunity

(2017) Daniel S. Green et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E3 ubiquitin ligase NKLAM ubiquitinates STAT1 and positively regulates STAT1-mediated transcriptional activity

(2016) Donald W. Lawrence et al.   CELLULAR SIGNALLING

The unique role of STAT2 in constitutive and IFN-induced transcription and antiviral responses

(2016) Katarzyna Blaszczyk et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response

(2016) Håkan C. Steen et al.   JOURNAL OF CELL SCIENCE

STAT2/IRF9 directs a prolonged ISGF3-like transcriptional response and antiviral activity in the absence of STAT1

(2015) Katarzyna Blaszczyk et al.   BIOCHEMICAL JOURNAL

IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer

(2015) K Abiko et al.   BRITISH JOURNAL OF CANCER

Mutations in the linker domain affect phospho-STAT3 function and suggest targets for interrupting STAT3 activity

(2015) Claudia Mertens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm

(2014) Iraz T. Aydin et al.   JNCI-Journal of the National Cancer Institute

IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage

(2013) HyeonJoo Cheon et al.   EMBO JOURNAL

Identification of Missing Proteins in the neXtProt Database and Unregistered Phosphopeptides in the PhosphoSitePlus Database As Part of the Chromosome-Centric Human Proteome Project

(2013) Takashi Shiromizu et al.   JOURNAL OF PROTEOME RESEARCH

Stat2 loss leads to cytokine-independent, cell-mediated lethality in LPS-induced sepsis

(2013) W. Alazawi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of STAT2 Serine 287 as a Novel Regulatory Phosphorylation Site in Type I Interferon-induced Cellular Responses

(2012) Håkan C. Steen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity

(2011) Catherine A. Vaughan et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms

(2011) P de Bie et al.   CELL DEATH AND DIFFERENTIATION

PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

(2011) P. V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

I B kinase   (IKK ) regulates the balance between type I and type II interferon responses

(2011) S.-L. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAT2 Contributes to Promotion of Colorectal and Skin Carcinogenesis

(2010) A. M. Gamero et al.   Cancer Prevention Research

Ubiquitin networks in cancer

(2010) Vladimir Kirkin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Viral hijacking of the host ubiquitin system to evade interferon responses

(2010) Kasinath Viswanathan et al.   CURRENT OPINION IN MICROBIOLOGY

Paramyxovirus Disruption of Interferon Signal Transduction: STATus Report

(2009) Aparna Ramachandran et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

NS5 of Dengue Virus Mediates STAT2 Binding and Degradation

(2009) J. Ashour et al.   JOURNAL OF VIROLOGY

Quantitative Phosphoproteomic Analysis of T Cell Receptor Signaling Reveals System-Wide Modulation of Protein-Protein Interactions

(2009) V. Mayya et al.   Science Signaling

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

Innate immune response to viral infection

(2008) Shohei Koyama et al.   CYTOKINE

Basal Ubiquitin-independent Internalization of Interferon α Receptor Is Prevented by Tyk2-mediated Masking of a Linear Endocytic Motif

(2008) K. G. Suresh Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERK and the F-box Protein βTRCP Target STAT1 for Degradation

(2008) Surinder M. Soond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human cytomegalovirus interferes with signal transducer and activator of transcription (STAT) 2 protein stability and tyrosine phosphorylation

(2008) V. T. K. Le et al.   JOURNAL OF GENERAL VIROLOGY