Rutin‐protected BisGMA ‐induced cytotoxicity, genotoxicity, and apoptosis in macrophages through the reduction of the mitochondrial apoptotic pathway and induction of antioxidant enzymes

Expression of pro-inflammatory cytokines and mediators induced by Bisphenol A via ERK-NFκB and JAK1/2-STAT3 pathways in macrophages

(2019) Fu-Mei Huang et al.   ENVIRONMENTAL TOXICOLOGY

Rutin and ascorbic acid cooperation in antioxidant and antiapoptotic effect on human skin keratinocytes and fibroblasts exposed to UVA and UVB radiation

(2019) Agnieszka Gęgotek et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

M1 and M2 macrophage polarization and potentially therapeutic naturally occurring compounds

(2019) Youhan Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Rutin abrogates manganese—Induced striatal and hippocampal toxicity via inhibition of iron depletion, oxidative stress, inflammation and suppressing the NF-κB signaling pathway

(2019) Kpobari W. Nkpaa et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Rutin hydrate inhibits apoptosis in the brains of cadmium chloride-treated rats via preserving the mitochondrial integrity and inhibiting endoplasmic reticulum stress

(2019) Dalia G. Mostafa et al.   NEUROLOGICAL RESEARCH

Increased mitochondrial NADPH oxidase 4 (NOX4) expression in aging is a causative factor in aortic stiffening

(2019) Chandrika Canugovi et al.   Redox Biology

Comparison of human monocyte derived macrophages and THP1-like macrophages as in vitro models for M. tuberculosis infection

(2019) Abhilasha Madhvi et al.   COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

Protective effect of rutin against carbon tetrachloride-induced oxidative stress, inflammation and apoptosis in mouse kidney associated with the ceramide, MAPKs, p53 and calpain activities

(2018) Jie-Qiong Ma et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Modulatory role of rutin on 2,5-hexanedione-induced chromosomal and DNA damage in rats: validation of computational predictions

(2018) Aliyu Muhammad et al.   DRUG AND CHEMICAL TOXICOLOGY

Rutin, a quercetin glycoside, alleviates acute endotoxemic kidney injury in C57BL/6 mice via suppression of inflammation and up-regulation of antioxidants and SIRT1

(2018) Mohammad-Reza Khajevand-Khazaei et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effects of rutin on lipopolysaccharide-induced heart injury in mice

(2018) Liu Xianchu et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

BisGMA analogues as monomers and diluents for dental restorative composite materials

(2018) Rohit Srivastava et al.   Materials Science & Engineering C-Materials for Biological Applications

Evaluation of phenotypic and functional stability of RAW 264.7 cell line through serial passages

(2018) Bartłomiej Taciak et al.   PLoS One

Cadmium nitrate-induced neuronal apoptosis is protected by N-acetyl-l-cysteine via reducing reactive oxygen species generation and mitochondria dysfunction

(2018) Chien-Ying Lee et al.   BIOMEDICINE & PHARMACOTHERAPY

Safrole induced cytotoxicity, DNA damage, and apoptosis in macrophages via reactive oxygen species generation and Akt phosphorylation

(2018) Kuang-Jen Chien et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Rutin Attenuates Vancomycin-Induced Nephrotoxicity by Ameliorating Oxidative Stress, Apoptosis, and Inflammation in Rats

(2018) Shaoqi Qu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A novel rutin-fucoidan complex based phytotherapy for cervical cancer through achieving enhanced bioavailability and cancer cell apoptosis

(2018) Murugesan Sathiya Deepika et al.   BIOMEDICINE & PHARMACOTHERAPY

Bisphenol A exhibits cytotoxic or genotoxic potential via oxidative stress-associated mitochondrial apoptotic pathway in murine macrophages

(2018) Fu-Mei Huang et al.   FOOD AND CHEMICAL TOXICOLOGY

Protective effect of rutin isolated from Spermococe hispida against cobalt chloride-induced hypoxic injury in H9c2 cells by inhibiting oxidative stress and inducing apoptosis

(2018) Lakshmi Sundaram.R et al.   PHYTOMEDICINE

Long-term culture with lipopolysaccharide induces dose-dependent cytostatic and cytotoxic effects in THP-1 monocytes

(2017) Jennifer Mytych et al.   TOXICOLOGY IN VITRO

Modulation of reactive oxygen species production, apoptosis and cell cycle in pleural exudate cells of carrageenan-induced acute inflammation in rats by rutin

(2017) Stephen Adeniyi Adefegha et al.   Food & Function

Rutin hydrate ameliorates cadmium chloride-induced spatial memory loss and neural apoptosis in rats by enhancing levels of acetylcholine, inhibiting JNK and ERK1/2 activation and activating mTOR signalling

(2017) Ghada A. Abdel-Aleem et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Rutin Acid Ameliorates Neural Apoptosis Induced by Traumatic Brain Injury via Mitochondrial Pathways in Mice

(2016) Xiaofu Zhai et al.   NEUROIMMUNOMODULATION

Caspase-8 and Caspase-9 Functioned Differently at Different Stages of the Cyclic Stretch-Induced Apoptosis in Human Periodontal Ligament Cells

(2016) Yaqin Wu et al.   PLoS One

NOX4 NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease

(2015) Aleksandr E. Vendrov et al.   ANTIOXIDANTS & REDOX SIGNALING

Macrophage defense mechanisms against intracellular bacteria

(2015) Günter Weiss et al.   IMMUNOLOGICAL REVIEWS

3,4-Dihydroxytoluene, a metabolite of rutin, inhibits inflammatory responses in lipopolysaccharide-activated macrophages by reducing the activation of NF-κB signaling

(2014) Kang-Yi Su et al.   BMC Complementary and Alternative Medicine

ROS Function in Redox Signaling and Oxidative Stress

(2014) Michael Schieber et al.   CURRENT BIOLOGY

Rutin improves endotoxin-induced acute lung injury via inhibition of iNOS and VCAM-1 expression

(2014) Yi-Chun Huang et al.   ENVIRONMENTAL TOXICOLOGY

Rutin decreases lipopolysaccharide-induced acute lung injury via inhibition of oxidative stress and the MAPK–NF-κB pathway

(2014) Chung-Hsin Yeh et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antioxidant Mechanism of Rutin on Hypoxia-Induced Pulmonary Arterial Cell Proliferation

(2014) Qian Li et al.   MOLECULES

Rutin from Dendropanax morbifera Leveille Protects Human Dopaminergic Cells Against Rotenone Induced Cell Injury Through Inhibiting JNK and p38 MAPK Signaling

(2014) Se-Eun Park et al.   NEUROCHEMICAL RESEARCH

Effects of antioxidants on DNA-double strand breaks in human gingival fibroblasts exposed to methacrylate based monomers

(2013) Susanne Lottner et al.   DENTAL MATERIALS

The upregulation of tumour necrosis factor-α and surface antigens expression on macrophages by bisphenol A-glycidyl-methacrylate

(2012) Y.-H. Kuan et al.   INTERNATIONAL ENDODONTIC JOURNAL

The role of DNA damage and caspase activation in cytotoxicity and genotoxicity of macrophages induced by bisphenol-A-glycidyldimethacrylate

(2012) Y.-C. Li et al.   INTERNATIONAL ENDODONTIC JOURNAL

How much do resin-based dental materials release? A meta-analytical approach

(2011) K.L. Van Landuyt et al.   DENTAL MATERIALS

Bisphenol A-glycidyl methacrylate induces a broad spectrum of DNA damage in human lymphocytes

(2010) Kinga Drozdz et al.   ARCHIVES OF TOXICOLOGY

The role of reactive oxygen species and hemeoxygenase-1 expression in the cytotoxicity, cell cycle alteration and apoptosis of dental pulp cells induced by BisGMA

(2010) Mei-Chi Chang et al.   BIOMATERIALS

Mitochondria and cell death: outer membrane permeabilization and beyond

(2010) Stephen W. G. Tait et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death

(2009) Subhadip Raychaudhuri et al.   APOPTOSIS

Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts

(2009) Ebru Urcan et al.   DENTAL MATERIALS

Rutin inhibits hydrogen peroxide-induced apoptosis through regulating reactive oxygen species mediated mitochondrial dysfunction pathway in human umbilical vein endothelial cells

(2009) Guohua Gong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular Toxicology of Substances Released from Resin–Based Dental Restorative Materials

(2009) Athina Bakopoulou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES