Open conformation of tetraspanins shapes interaction partner networks on cell membranes

Structural insights into tetraspanin CD9 function

(2020) Rie Umeda et al.   Nature Communications

Tetraspanin CD53 Promotes Lymphocyte Recirculation by Stabilizing L-Selectin Surface Expression

(2020) Maria C. Demaria et al.   iScience

Targeting the Tetraspanins with Monoclonal Antibodies in Oncology: Focus on Tspan8/Co-029

(2019) Mathilde Bonnet et al.   Cancers

CD81 is a novel immunotherapeutic target for B cell lymphoma

(2019) Felipe Vences-Catalán et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling

(2019) Zev J. Greenberg et al.   JOURNAL OF IMMUNOLOGY

RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex

(2019) Deepti Soodgupta et al.   Cell Reports

Immune Targeting of Tetraspanins Involved in Cell Invasion and Metastasis

(2018) Felipe Vences-Catalán et al.   Frontiers in Immunology

The Many and Varied Roles of Tetraspanins in Immune Cell Recruitment and Migration

(2018) Louisa Yeung et al.   Frontiers in Immunology

CD19 alterations emerging after CD19-directed immunotherapy cause retention of the misfolded protein in the endoplasmic reticulum

(2018) Asen Bagashev et al.   MOLECULAR AND CELLULAR BIOLOGY

Pathogen lineage-based genome-wide association study identified CD53 as susceptible locus in tuberculosis

(2017) Yosuke Omae et al.   JOURNAL OF HUMAN GENETICS

CD19 Isoforms Enabling Resistance to CART-19 Immunotherapy Are Expressed in B-ALL Patients at Initial Diagnosis

(2017) Jeannette Fischer et al.   JOURNAL OF IMMUNOTHERAPY

Tetraspanin microdomains control localized protein kinase C signaling in B cells

(2017) Malou Zuidscherwoude et al.   Science Signaling

Tetraspanin microdomains control localized protein kinase C signaling in B cells

(2017) Malou Zuidscherwoude et al.   Science Signaling

The specificity of homomeric clustering of CD81 is mediated by its δ-loop

(2017) Yahya Homsi et al.   FEBS Open Bio

CD19-targeted CAR T-cell therapeutics for hematologic malignancies: interpreting clinical outcomes to date

(2016) Jae H. Park et al.   BLOOD

Resistance to anti-CD19/CD3 BiTE in acute lymphoblastic leukemia may be mediated by disrupted CD19 membrane trafficking

(2016) Friederike Braig et al.   BLOOD

Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket

(2016) Brandon Zimmerman et al.   CELL

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

Tetraspanin CD81 Promotes Tumor Growth and Metastasis by Modulating the Functions of T Regulatory and Myeloid-Derived Suppressor Cells

(2015) Felipe Vences-Catalán et al.   CANCER RESEARCH

Tetraspanins as therapeutic targets in hematological malignancy: a concise review

(2015) Kyle A. Beckwith et al.   Frontiers in Physiology

The Extracellular δ-Domain is Essential for the Formation of CD81 Tetraspanin Webs

(2014) Yahya Homsi et al.   BIOPHYSICAL JOURNAL

Solution Structure, Membrane Interactions, and Protein Binding Partners of the Tetraspanin Sm-TSP-2, a Vaccine Antigen from the Human Blood FlukeSchistosoma mansoni

(2014) Xinying Jia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tetraspanins at a glance

(2014) S. Charrin et al.   JOURNAL OF CELL SCIENCE

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The TspanC8 Subgroup of Tetraspanins Interacts with A Disintegrin and Metalloprotease 10 (ADAM10) and Regulates Its Maturation and Cell Surface Expression

(2012) Elizabeth J. Haining et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81

(2012) Sundaresan Rajesh et al.   JOURNAL OF VIROLOGY

Recent developments in classical density modification

(2010) Kevin Cowtan   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Lateral organization of membrane proteins: tetraspanins spin their web

(2009) Stéphanie Charrin et al.   BIOCHEMICAL JOURNAL

Sperm–egg adhesion and fusion in mammals

(2009) Peter Sutovsky   EXPERT REVIEWS IN MOLECULAR MEDICINE

CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields

(2009) K. Vanommeslaeghe et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Intron Evolution: Testing Hypotheses of Intron Evolution Using the Phylogenomics of Tetraspanins

(2009) Antonio Garcia-España et al.   PLoS One

Hepatocyte Permissiveness to Plasmodium Infection Is Conveyed by a Short and Structurally Conserved Region of the CD81 Large Extracellular Domain

(2008) Samir Yalaoui et al.   PLoS Pathogens