Targeting the Tetraspanins with Monoclonal Antibodies in Oncology: Focus on Tspan8/Co-029

Investigational therapies targeting CD37 for the treatment of B-cell lymphoid malignancies

(2018) Magdalena Witkowska et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Antibody-drug conjugates: Design and development for therapy and imaging in and beyond cancer, LabEx MAbImprove industrial workshop, July 27–28, 2017, Tours, France

(2018) Camille Martin et al.   mAbs

Evaluation of an Anti-HER2 Nanobody Labeled with 225Ac for Targeted α-Particle Therapy of Cancer

(2018) Marek Pruszynski et al.   MOLECULAR PHARMACEUTICS

Alpha-Emitters and Targeted Alpha Therapy in Oncology: from Basic Science to Clinical Investigations

(2018) Mehran Makvandi et al.   Targeted Oncology

Immune Targeting of Tetraspanins Involved in Cell Invasion and Metastasis

(2018) Felipe Vences-Catalán et al.   Frontiers in Immunology

Multi-factorial modulation of colorectal carcinoma cells motility – partial coordination by the tetraspanin Co-029/tspan8

(2017) Yingying Zhu et al.   Oncotarget

Tetraspanin 8 (TSPAN 8) as a potential target for radio-immunotherapy of colorectal cancer

(2017) Aurelie Maisonial-Besset et al.   Oncotarget

Antibody PEGylation in bioorthogonal pretargeting with trans-cyclooctene/tetrazine cycloaddition: in vitro and in vivo evaluation in colorectal cancer models

(2017) Aurélie Rondon et al.   Scientific Reports

Crystal Structure of a Full-Length Human Tetraspanin Reveals a Cholesterol-Binding Pocket

(2016) Brandon Zimmerman et al.   CELL

Tetraspanin CD37 protects against the development of B cell lymphoma

(2016) Charlotte M. de Winde et al.   JOURNAL OF CLINICAL INVESTIGATION

Les tétraspanines dans la physiopathologie de la peau

(2016) Ingrid Masse et al.   M S-MEDECINE SCIENCES

Establishment of the In Vivo Efficacy of Pretargeted Radioimmunotherapy Utilizing Inverse Electron Demand Diels-Alder Click Chemistry

(2016) Jacob L. Houghton et al.   MOLECULAR CANCER THERAPEUTICS

Therapeutic targeting of tetraspanin8 in epithelial ovarian cancer invasion and metastasis

(2016) C S Park et al.   ONCOGENE

Targeted Radionuclide Therapy of Melanoma

(2016) Abdullah Norain et al.   SEMINARS IN NUCLEAR MEDICINE

Pancreatic cancer stem cell markers and exosomes - the incentive push

(2016) Sarah Heiler et al.   WORLD JOURNAL OF GASTROENTEROLOGY

EWI-2 negatively regulates TGF-β signaling leading to altered melanoma growth and metastasis

(2015) Hong-Xing Wang et al.   CELL RESEARCH

Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL Network Phase II Trial

(2015) S Ferrero et al.   LEUKEMIA

The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding

(2015) Shijing Yue et al.   Oncotarget

Pretargeted imaging using bioorthogonal chemistry in mice

(2014) Raffaella Rossin et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Tetraspanins at a glance

(2014) S. Charrin et al.   JOURNAL OF CELL SCIENCE

First-in-Human Molecular Imaging of HER2 Expression in Breast Cancer Metastases Using the 111In-ABY-025 Affibody Molecule

(2014) J. Sorensen et al.   JOURNAL OF NUCLEAR MEDICINE

Effect of an anti-human Co-029/tspan8 mouse monoclonal antibody on tumor growth in a nude mouse model

(2014) Naouel Ailane et al.   Frontiers in Physiology

Tetraspanins in Extracellular Vesicle Formation and Function

(2014) Zoraida Andreu et al.   Frontiers in Immunology

Integrin-Free Tetraspanin CD151 Can Inhibit Tumor Cell Motility upon Clustering and Is a Clinical Indicator of Prostate Cancer Progression

(2013) T. D. Palmer et al.   CANCER RESEARCH

General overview of radioimmunotherapy of solid tumors

(2013) Isabelle Navarro-Teulon et al.   Immunotherapy

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

Tetraspanin CD151 as a target for antibody-based cancer immunotherapy

(2011) Jean-François Haeuw et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Analysis of patient survival in a Phase I trial of systemic targeted α-therapy for metastatic melanoma

(2011) Barry J Allen et al.   Immunotherapy

Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion

(2010) O Berthier-Vergnes et al.   BRITISH JOURNAL OF CANCER

E-Cadherin/p120-Catenin and Tetraspanin Co-029 Cooperate for Cell Motility Control in Human Colon Carcinoma

(2010) C. Greco et al.   CANCER RESEARCH

Sequential Cytarabine and  -Particle Immunotherapy with Bismuth-213-Lintuzumab (HuM195) for Acute Myeloid Leukemia

(2010) T. L. Rosenblat et al.   CLINICAL CANCER RESEARCH

Lateral organization of membrane proteins: tetraspanins spin their web

(2009) Stéphanie Charrin et al.   BIOCHEMICAL JOURNAL

A novel therapeutic strategy with anti-CD9 antibody in gastric cancers

(2009) Taisei Nakamoto et al.   JOURNAL OF GASTROENTEROLOGY

Targeting of tetraspanin proteins — potential benefits and strategies

(2008) Martin E. Hemler   NATURE REVIEWS DRUG DISCOVERY