Crystal Structure of African Swine Fever Virus dUTPase Reveals a Potential Drug Target

From “A”IV to “Z”IKV: Attacks from Emerging and Re-emerging Pathogens

(2018) George F. Gao   CELL

CASTp 3.0: computed atlas of surface topography of proteins

(2018) Wei Tian et al.   NUCLEIC ACIDS RESEARCH

African swine fever: A re-emerging viral disease threatening the global pig industry

(2018) P.J. Sánchez-Cordón et al.   VETERINARY JOURNAL

A proteomic atlas of the African swine fever virus particle

(2018) Alí Alejo et al.   JOURNAL OF VIROLOGY

Emergence of African Swine Fever in China, 2018

(2018) Xintao Zhou et al.   Transboundary and Emerging Diseases

Crystal structure of the C-terminal fragment of NS1 protein from yellow fever virus

(2017) Haiyuan Wang et al.   Science China-Life Sciences

African Swine Fever Virus: A Review

(2017) et al.   Viruses-Basel

Transmission routes of African swine fever virus to domestic pigs: current knowledge and future research directions

(2016) Claire Guinat et al.   VETERINARY RECORD

Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells

(2016) Erik C Hansen et al.   eLife

Life without dUTPase

(2016) Csaba Kerepesi et al.   Frontiers in Microbiology

Structural genomics for drug design against the pathogenCoxiella burnetii

(2015) Matthew C. Franklin et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The EBV-Encoded dUTPase Activates NF- B through the TLR2 and MyD88-Dependent Signaling Pathway

(2014) M.-E. Ariza et al.   JOURNAL OF IMMUNOLOGY

dUTPases, the unexplored family of signalling molecules

(2013) José R Penadés et al.   CURRENT OPINION IN MICROBIOLOGY

Molecular Modeling ofMycobacterium TuberculosisdUTpase: Docking and Catalytic Mechanism Studies

(2012) Teodorico C. Ramalho et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Abundant Non-canonical dUTP Found in Primary Human Macrophages Drives Its Frequent Incorporation by HIV-1 Reverse Transcriptase

(2011) Edward M. Kennedy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Crystal Structure of theLeishmania majorDeoxyuridine Triphosphate Nucleotidohydrolase in Complex with Nucleotide Analogues, dUMP, and Deoxyuridine

(2011) Glyn R. Hemsworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design

(2011) G. Lu et al.   JOURNAL OF VIROLOGY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Keeping Uracil Out of DNA: Physiological Role, Structure and Catalytic Mechanism of dUTPases

(2008) Beáta G Vértessy et al.   ACCOUNTS OF CHEMICAL RESEARCH