A systems genetics study of swine illustrates mechanisms underlying human phenotypic traits

Genetic dissection of blood lipid traits by integrating genome-wide association study and gene expression profiling in a porcine model

(2013) Congying Chen et al.   BMC GENOMICS

A joint genomewide association analysis of pig leg weakness and its related traits in an F2 population and a Sutai population1

(2013) Y. M. Guo et al.   JOURNAL OF ANIMAL SCIENCE

Genome-wide association mapping of blood cell traits in mice

(2013) Richard C. Davis et al.   MAMMALIAN GENOME

Genome-Wide Association Study of Meat Quality Traits in a White Duroc×Erhualian F2 Intercross and Chinese Sutai Pigs

(2013) Junwu Ma et al.   PLoS One

GWAS of blood cell traits identifies novel associated loci and epistatic interactions in Caucasian and African-American children

(2012) Jin Li et al.   HUMAN MOLECULAR GENETICS

Analyses of pig genomes provide insight into porcine demography and evolution

(2012) Martien A. M. Groenen et al.   NATURE

Genetic Analysis of Hematological Parameters in Incipient Lines of the Collaborative Cross

(2012) Samir N. P. Kelada et al.   G3-Genes Genomes Genetics

Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation

(2012) Jun Zhu et al.   PLOS BIOLOGY

Detection of quantitative trait loci for growth- and fatness-related traits in a large-scale White Duroc × Erhualian intercross pig population

(2011) H. Ai et al.   ANIMAL GENETICS

Identification of a second gene associated with variation in vertebral number in domestic pigs

(2011) Satoshi Mikawa et al.   BMC GENETICS

A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort

(2011) D. M. Greenawalt et al.   GENOME RESEARCH

Heterozygous inactivation of Gnas in adipose-derived mesenchymal progenitor cells enhances osteoblast differentiation and promotes heterotopic ossification

(2011) Robert J Pignolo et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Variants modulating the expression of a chromosome domain encompassing PLAG1 influence bovine stature

(2011) Latifa Karim et al.   NATURE GENETICS

Hypocholesterolemia is associated negatively with hemolysate lipid peroxidation in sickle cell anemia patients

(2010) Oztas Er Yesim et al.   CLINICAL AND EXPERIMENTAL MEDICINE

The repression of Notch signaling occurs via the destabilization of mastermind-like 1 by Mesp2 and is essential for somitogenesis

(2010) N. Sasaki et al.   DEVELOPMENT

Disabled-2 is required for mesoderm differentiation of murine embryonic stem cells

(2010) Chien-Ling Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

Automated Network Analysis Identifies Core Pathways in Glioblastoma

(2010) Ethan Cerami et al.   PLoS One

The segmentation clock mechanism moves up a notch

(2010) Sarah Gibb et al.   TRENDS IN CELL BIOLOGY

Hepcidin in Obese Children as a Potential Mediator of the Association between Obesity and Iron Deficiency

(2009) Emanuele Miraglia del Giudice et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The transcriptional network for mesenchymal transformation of brain tumours

(2009) Maria Stella Carro et al.   NATURE

Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

(2009) Santhi K Ganesh et al.   NATURE GENETICS

Iron deficiency and obesity: the contribution of inflammation and diminished iron absorption

(2009) James P McClung et al.   NUTRITION REVIEWS

Dab2 stabilizes Axin and attenuates Wnt/β-catenin signaling by preventing protein phosphatase 1 (PP1)–Axin interactions

(2009) Y Jiang et al.   ONCOGENE

Design of a High Density SNP Genotyping Assay in the Pig Using SNPs Identified and Characterized by Next Generation Sequencing Technology

(2009) Antonio M. Ramos et al.   PLoS One

Meta-Analysis of Genome-Wide Scans for Human Adult Stature Identifies Novel Loci and Associations with Measures of Skeletal Frame Size

(2009) Nicole Soranzo et al.   PLoS Genetics

A genome-wide scan for quantitative trait loci affecting limb bone lengths and areal bone mineral density of the distal femur in a White Duroc × Erhualian F2 population

(2008) Huirong Mao et al.   BMC GENETICS

Quantitative trait loci for porcine baseline erythroid traits at three growth ages in a White Duroc × Erhualian F2 resource population

(2008) Zhengzhi Zou et al.   MAMMALIAN GENOME

Transcription analysis in the MeLiM swine model identifies RACK1 as a potential marker of malignancy for human melanocytic proliferation

(2008) Giorgia Egidy et al.   Molecular Cancer

Variations in DNA elucidate molecular networks that cause disease

(2008) Yanqing Chen et al.   NATURE

Genetics of gene expression and its effect on disease

(2008) Valur Emilsson et al.   NATURE

Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks

(2008) Jun Zhu et al.   NATURE GENETICS

Many sequence variants affecting diversity of adult human height

(2008) Daniel F Gudbjartsson et al.   NATURE GENETICS

Mapping the Genetic Architecture of Gene Expression in Human Liver

(2008) Eric E Schadt et al.   PLOS BIOLOGY