Unique immunological profile in patients with COVID-19

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China

(2020) Qiurong Ruan et al.   INTENSIVE CARE MEDICINE

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

Fatal COVID-19 infections: Is NK cell dysfunction a link with autoimmune HLH?

(2020) Mohammed S. Osman et al.   AUTOIMMUNITY REVIEWS

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

The Innate Immune System: Fighting on the Front Lines or Fanning the Flames of COVID-19?

(2020) Julia L. McKechnie et al.   Cell Host & Microbe

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Functional exhaustion of antiviral lymphocytes in COVID-19 patients

(2020) Meijuan Zheng et al.   Cellular & Molecular Immunology

Reduced Siglec‐7 expression on NK cells predicts NK cell dysfunction in primary hepatocellular carcinoma

(2020) L. Tao et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Characteristics and prognostic factors of disease severity in patients with COVID-19: The Beijing experience

(2020) Ying Sun et al.   JOURNAL OF AUTOIMMUNITY

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Viral and host factors related to the clinical outcome of COVID-19

(2020) Xiaonan Zhang et al.   NATURE

Could hemophagocytic lymphohistiocytosis be the core issue of severe COVID-19 cases?

(2020) Violetta Opoka-Winiarska et al.   BMC Medicine

Immunological and inflammatory profiles in mild and severe cases of COVID-19

(2020) Jin-Wen Song et al.   Nature Communications

Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

(2020) Sara De Biasi et al.   Nature Communications

Natural killer cell immunotypes related to COVID-19 disease severity

(2020) Christopher Maucourant et al.   Science Immunology

Harnessing innate immunity in cancer therapy

(2019) Olivier Demaria et al.   NATURE

Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells

(2019) Nicole Marquardt et al.   Nature Communications

The Ikaros family in lymphocyte development

(2018) Beate Heizmann et al.   CURRENT OPINION IN IMMUNOLOGY

Lack of Siglec-7 expression identifies a dysfunctional natural killer cell subset associated with liver inflammation and fibrosis in chronic HCV infection

(2015) Stefania Varchetta et al.   GUT

The Transcription Factor NFAT Promotes Exhaustion of Activated CD8 + T Cells

(2015) Gustavo J. Martinez et al.   IMMUNITY

Increased Tim-3 expression in peripheral NK cells predicts a poorer prognosis and Tim-3 blockade improves NK cell-mediated cytotoxicity in human lung adenocarcinoma

(2015) Liyun Xu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Peripheral natural killer cell maturation depends on the transcription factor Aiolos

(2014) M. L. Holmes et al.   EMBO JOURNAL

Tim-3 Negatively Mediates Natural Killer Cell Function in LPS-Induced Endotoxic Shock

(2014) Hongyan Hou et al.   PLoS One

HIV Infection Deregulates Tim-3 Expression on Innate Cells

(2013) Constance A.M. Finney et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Adult haemophagocytic syndrome

(2013) Manuel Ramos-Casals et al.   LANCET

Aberrantly Decreased Levels of NKG2D Expression in Children with Kawasaki Disease

(2013) X. Ge et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Tim-3/galectin-9 signaling pathway mediates T-cell dysfunction and predicts poor prognosis in patients with hepatitis B virus-associated hepatocellular carcinoma

(2012) Hang Li et al.   HEPATOLOGY