Article
Biochemistry & Molecular Biology
Le Ma, Wenwen Jiang, Xiaowei Xun, Mingzhuo Liu, Xiao Han, Jiale Xie, Maohu Wang, Quanchao Zhang, Zhaoxiang Peng, Haiyong Ao
Summary: Utilizing mussel-inspired chemistry, a polydopamine/polyethyleneimine coated bacterial cellulose was constructed with homogeneous silver nanoparticles (AgNPs). The obtained AgNPs@PPBC exhibited excellent antibacterial activities and cytocompatibility. In vivo assays showed that AgNPs@PPBC dressing could effectively treat infected wounds and promote wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Liang Zhang, Yuning Yu, Sen Zheng, Lvling Zhong, Juanqin Xue
Summary: A novel silver-based cellulose wound dressing was developed by adding graphene oxide and polydopamine to fix AgNPs onto bacterial cellulose. The composite material showed good conductivity and thermogenic properties, promoting wound healing while releasing Ag+ for antibacterial effects, with excellent biocompatibility demonstrated in vitro cytotoxicity tests.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Physical
Mahdi Barjasteh, Seyed Mohsen Dehnavi, Shahab Ahmadi Seyedkhani, Seyed Yahya Rahnamaee, Mortaza Golizadeh
Summary: The novel silver-based metal-organic framework (SOF) was synthesized using an environmentally-friendly process, and it was incorporated into a dual nanosized chitosan/bacterial cellulose (CS/BC) fibrous composite. The resulting CS/BC-SOF nanocomposite showed excellent antibacterial activity against E. coli and S. aureus strains, and it also exhibited high biocompatibility and enhanced wound healing in animal studies. The synthesized nanocomposites have great potential for use as wound dressing platforms.
SURFACES AND INTERFACES
(2023)
Article
Microbiology
Daria Ciecholewska-Jusko, Adam Junka, Karol Fijalkowski
Summary: This study successfully achieved sustained release of octenidine dihydrochloride through modified bacterial cellulose materials, demonstrating antibacterial activity and exudate absorption capacity, with no cytotoxicity. The findings suggest the potential application of cross-linked bacterial cellulose impregnated with octenidine dihydrochloride in wound treatment.
MICROBIOLOGICAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Gabriela Isopencu, Iuliana Deleanu, Cristina Busuioc, Ovidiu Oprea, Vasile-Adrian Surdu, Mihaela Bacalum, Roberta Stoica, Anicuta Stoica-Guzun
Summary: Bacterial cellulose (BC) is a biopolymer studied intensively for biomedical applications. However, it lacks antimicrobial activity and has limited water retention capacity. To address these limitations, BC composites with carboxymethyl cellulose (CMC) and turmeric extract (TE) were developed using citric acid (CA) as the crosslinking agent. These composites showed high swelling degrees, adsorbing exudate from chronic wounds, and exhibited potential antibacterial properties against Escherichia coli, Staphylococcus aureus, and Candida albicans. The composites were also found to be non-toxic to fibroblast cells, making them promising candidates for wound dressing applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Md Kaiser Haider, Azeem Ullah, Muhammad Nauman Sarwar, Yusuke Saito, Lei Sun, Soyoung Park, Ick Soo Kim
Summary: The study demonstrates the synthesis of CuO nanoparticles on electrospun cellulose nanofibers using alkali lignin as a reducing agent, showing potential as wound dressing material with excellent antibacterial efficacy and cell compatibility.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Applied
Chennan Liu, Junhong Ling, Li-Ye Yang, Xiao-kun Ouyang, Nan Wang
Summary: The development of a new type of dressing to combat bacterial resistance is of great importance. A carbon nitride-polydopamine-silver complex (C3N4-PDA-Ag) was prepared using C3N4 and silver nanoparticles (Ag NPs) to achieve a synergistic antimicrobial effect. The C3N4-PDA-Ag complex was further modified with chitosan (CS) to form a C3N4-PDA-Ag@CS film. The results showed that the C3N4-PDA-Ag@CS film exhibited superior antibacterial activity and biocompatibility, and promoted wound healing in infected mice.
CARBOHYDRATE POLYMERS
(2023)
Article
Materials Science, Paper & Wood
Nghi Thi-Phuong Nguyen, Huy Hoang Nguyen, Hoan Ngoc Doan, Kien Trung Pham, Khiem Van Nguyen, Binh Thanh Vu, Tin Dai Luong, Bach Thang Phan, Hanh Kieu Thi Ta, Ngoc Quyen Tran, Tuan-Ngan Tang, Nhi Ngoc-Thao Dang, Thi-Hiep Nguyen
Summary: The study found that adding chitosan oligosaccharide to bacterial cellulose membranes can improve their hemostatic properties, although it may decrease the mechanical strength of the membranes. The modified bacterial cellulose membrane with 2 w/v% chitosan oligosaccharide solution (BC-COS2) demonstrated excellent hemostasis promotion in in vitro and in vivo experiments.
Article
Chemistry, Multidisciplinary
Hsiu-Wen Chien, Ming-Yen Tsai, Chia-Jung Kuo, Ching-Lo Lin
Summary: A method was developed to create PDA/PEI/Ag nanocomplexes on cellulose filter papers, achieving significant bacterial reduction through gravity filtration. The technology could be utilized for industrial production and treatment of microbial-contaminated drinking water.
Review
Engineering, Environmental
Mehdi Rasouli, Masoud Soleimani, Simzar Hosseinzadeh, Javad Ranjbari
Summary: Despite advancements in wound healing, delayed wound closure remains a global health challenge. Bacterial cellulose (BC) has attracted attention for its features in wound healing and tissue regeneration, but modifications are necessary to enhance antibacterial properties and cell adhesion.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2023)
Article
Pharmacology & Pharmacy
Paul-Octavian Stanescu, Ionut-Cristian Radu, Rebeca Leu Alexa, Ariana Hudita, Eugenia Tanasa, Jana Ghitman, Oana Stoian, Aristidis Tsatsakis, Octav Ginghina, Catalin Zaharia, Mikhail Shtilman, Yaroslav Mezhuev, Bianca Galateanu
Summary: In this study, biocomposites based on bacterial cellulose and chitosan membranes tailored with antimicrobial loaded poly(N-isopropylacrylamide)/polyvinyl alcohol nanoparticles were prepared. Investigations on the chemistry, structure, morphology, size distribution, and in vitro release behaviors of the materials were conducted, showing promising characteristics for their potential as a biocompatible and antibacterial wound dressing.
Article
Dermatology
Ran Zhao, Chenyuyao Zhao, Yushen Zhang, Yi Wan, Yibing Wang
Summary: This study retrospectively reviewed cases from the past 5 years and found that bacterial cellulose dressing had better outcomes compared to allogenic skin in paediatric burn wounds after dermabrasion surgery. The BCD group had longer surgery time, shorter healing time, fewer dressing changes, and lower rates of skin grafting.
INTERNATIONAL WOUND JOURNAL
(2023)
Article
Materials Science, Biomaterials
Zhifei Yang, Fangfang Feng, Wenwen Jiang, Le Ma, Mingzhuo Liu, Kai Li, Yizao Wan, Haiyong Ao
Summary: A copper ion-loaded cellulose dressing with excellent antibacterial performance was successfully prepared through the co-deposition of polydopamine and copper ions. The dressing retains the original nanopore structure of cellulose and promotes wound healing.
BIOMATERIALS ADVANCES
(2022)
Review
Biochemistry & Molecular Biology
Saharman Gea, Imam Budi Putra, Dharma Lindarto, Khatarina Meldawati Pasaribu, Yanggi Saraswati, Myrtha Karina, Ronn Goei, Alfred Iing Yoong Tok
Summary: Diabetic foot ulcer is a common complication of diabetes mellitus. This study focused on the development of BC/Z. acanthopodium microencapsulated wound dressing composites and evaluated their potential as a DFU wound dressing. The results showed that the wound dressings exhibited good antibacterial effect and accelerated the wound closure process.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Biochemistry & Molecular Biology
Shuaiwen Hou, Zhaopeng Xia, Jiajun Pan, Ning Wang, Hanchao Gao, Jingli Ren, Xuekui Xia
Summary: This review provides a comprehensive introduction to the microbial production of bacterial cellulose (BC) and discusses the functional deficiencies of BC as a wound dressing. It highlights the application of BC composites in wound management and prospects for low-cost production and high-value-added product development of BC-based wound dressings.
MACROMOLECULAR BIOSCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Prasanna S. Bakshi, D. Selvakumar, K. Kadirvelu, N. S. Kumar
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2020)
Article
Chemistry, Physical
T. Krishnaveni, K. Lakshmi, K. Kadirvelu, M. Kaveri
Review
Environmental Sciences
Srinivas Ravi Manoj, Chinnannan Karthik, Krishna Kadirvelu, Padikasan Indra Arulselvi, Thangavel Shanmugasundaram, Benedict Bruno, Mani Rajkumar
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2020)
Article
Toxicology
Monika Jain, Vinod Kumar Garg, Rashmi Paliwal, Krishna Kadirvelu, Smita Chaudhry
Summary: The study used chemically treated sunflower stems to adsorb Cd(II), and experimental results under optimized conditions showed a removal rate of 99.8%, in agreement with model predictions.
Article
Engineering, Biomedical
Sankaralingam Kanagasubbulakshmi, Krishnasamy Lakshmi, Krishna Kadirvelu
Summary: A prosthetic scaffold development utilizing fluorescent nanofiber was reported to enhance reepithelialization in wistar albino rats. The novel approach involved constructing a biocompatible fluorescent nanofiber and assessing its biodegradation and antimicrobial properties to monitor tissue regeneration effectively. The developed scaffold not only supported tissue regeneration but also acted as an antimicrobial agent, showing promising results for infection free soft tissue regeneration.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2021)
Article
Environmental Sciences
Seema Joshi, Navish Kataria, V. K. Garg, K. Kadirvelu
Article
Environmental Sciences
Sathisaran Umamaheswari, Sheela Priyadarshinee, Monojit Bhattacharjee, Krishna Kadirvelu, Mathan Ramesh
Summary: The study shows that polystyrene microplastics induce various toxic effects in zebrafish, including disrupting the antioxidant defense system, causing histopathological lesions, and altering gene expression patterns.
Article
Environmental Sciences
Kannan Maharajan, Sellamani Muthulakshmi, Chinnannan Karthik, Bojan Nataraj, Kanthan Nambirajan, Devan Hemalatha, Swaminathan Jiji, Krishna Kadirvelu, Ke-chun Liu, Mathan Ramesh
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Biology
Naveen Kumar Kalagatur, Elsayed Fathi Abd-Allah, Sudhakar Poda, Krishna Kadirvelu, Abeer Hashem, Venkataramana Mudili, Chandranayaka Siddaiah
Summary: The study revealed that DON induces apoptotic demise in neuronal cells through oxidative stress, while pre-treatment with 1mM of quercetin (QUE) can counteract the neurotoxic effects of DON and protect cells from damage.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Srividya Swaminathan, Jebiti Haribabu, Naveen Kumar Kalagatur, Maroli Nikhil, Nithya Balakrishnan, Nattamai S. P. Bhuvanesh, Krishna Kadirvelu, Ponmalai Kolandaivel, Ramasamy Karvembu
Summary: The synthesis of fourteen new Ru-II-arene complexes were characterized and found to exhibit high toxicity towards IMR-32 cancer cells, with two complexes showing the highest activity and the ability to induce apoptosis and cell cycle arrest. These complexes also demonstrated good binding affinity with receptors commonly overexpressed in cancer cells.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Thenmozhi Sukumar, Krishna Kadirvelu
Summary: A novel composite core-shell nanofibers with improved mechanical strength and fire resistance were prepared using co-axial electrospinning technique. The core-shell morphology and presence of metal oxide were confirmed through imaging and analysis techniques. The thermal, chemical, and mechanical properties were studied, and the fire retardant properties were tested. The results demonstrated the potential of the prepared material for fire resistance applications.
Article
Chemistry, Multidisciplinary
S. Thenmozhi, N. Dharmaraj, K. Kadirvelu
Summary: In this study, palladium oxide nanofibers (PdO NF) with a diameter of 75 nm were prepared by electrospinning technique and used as catalysts for the cross-coupling of challenging bromo, chloro and fluoro benzonitriles. The successfulness and efficiency of this catalytic system were confirmed by the coupling products and proposed mechanism.
Article
Chemistry, Multidisciplinary
T. Krishnaveni, M. Kaveri, K. Kadirvelu
Summary: Palladium(ii) oxide nanoparticles were prepared using a hydrothermal method with quercetin as a capping agent, which showed good catalytic activity in the synthesis of propargylamines. The catalyst exhibited high turnover number and frequency, as well as excellent recyclability for multiple cycles.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Physical
T. Krishnaveni, K. Lakshmi, M. Kaveri, K. Kadirvelu
MOLECULAR CATALYSIS
(2020)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
