TRPV4-Mediated Epithelial Junction Disruption in Allergic Rhinitis Triggered by House Dust Mites

The Transient Receptor Potential Channel Vanilloid 1 (TRPV1) is Critical in Innate Airway Epithelial Responses to Protease Allergens

(2020) Caspar Schiffers et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Physical and immunological barrier of human primary nasal epithelial cells from non-allergic and allergic donors

(2020) Carolin Bergougnan et al.   World Allergy Organization Journal

Epithelial barriers in allergy and asthma

(2020) Peter W. Hellings et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Cytokine and inflammatory mediator effects on TRPV4 function in choroid plexus epithelial cells

(2019) Stefanie Simpson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

House dust mites activate nociceptor–mast cell clusters to drive type 2 skin inflammation

(2019) Nadine Serhan et al.   NATURE IMMUNOLOGY

Emerging roles of the protease allergen Der p 1 in house dust mite–induced airway inflammation

(2018) Andy Chevigné et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

TRPV4 inhibition attenuates stretch-induced inflammatory cellular responses and lung barrier dysfunction during mechanical ventilation

(2018) N. Pairet et al.   PLoS One

Barrier dysfunction in the nasal allergy

(2018) Ayumi Fukuoka et al.   ALLERGOLOGY INTERNATIONAL

Transient Receptor Potential Ion Channels Mediate Adherens Junctions Dysfunction in a Toluene Diisocyanate-Induced Murine Asthma Model

(2018) Lihong Yao et al.   TOXICOLOGICAL SCIENCES

Silica nanoparticles inhibit the cation channel TRPV4 in airway epithelial cells

(2017) Alicia Sanchez et al.   Particle and Fibre Toxicology

Decreased Expression of E-cadherin and ZO-1 in the Nasal Mucosa of Patients with Allergic Rhinitis: Altered Regulation of E-cadherin by IL-4, IL-5, and TNF-alpha

(2016) Hyun-Ji Lee et al.   American Journal of Rhinology & Allergy

Capsaicin for Rhinitis

(2016) Wytske Fokkens et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Impaired barrier function in patients with house dust mite–induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression

(2016) Brecht Steelant et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Barrier Epithelial Cells and the Control of Type 2 Immunity

(2015) Hamida Hammad et al.   IMMUNITY

House Dust Mite Respiratory Allergy: An Overview of Current Therapeutic Strategies

(2015) Moisés A. Calderón et al.   Journal of Allergy and Clinical Immunology-In Practice

Epithelial barrier function: At the front line of asthma immunology and allergic airway inflammation

(2014) Steve N. Georas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Sensitisation of TRPV4 by PAR2 is independent of intracellular calcium signalling and can be mediated by the biased agonist neutrophil elastase

(2014) Silvia Sostegni et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

TRPV4-Mediated Calcium Influx and Ciliary Activity in Human Native Airway Epithelial Cells

(2013) Lisa Alenmyr et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Transient receptor potential (TRP) channels in the airway: role in airway disease

(2013) M S Grace et al.   BRITISH JOURNAL OF PHARMACOLOGY

Protease-activated Receptor 2 (PAR2) Protein and Transient Receptor Potential Vanilloid 4 (TRPV4) Protein Coupling Is Required for Sustained Inflammatory Signaling

(2013) Daniel P. Poole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

House dust mite allergen Der p 1 effects on sinonasal epithelial tight junctions

(2013) Oswaldo A. Henriquez et al.   International Forum of Allergy & Rhinology

Epidermal growth factor receptor signalling contributes to house dust mite-induced epithelial barrier dysfunction

(2010) I. H. Heijink et al.   EUROPEAN RESPIRATORY JOURNAL

Induction of IL-6 and IL-8 by House Dust Mite Allergen Der p1 in Cultured Human Nasal Epithelial Cells Is Associated with PAR/PI3K/NFĸB Signaling

(2010) Jianbo Shi et al.   ORL-Journal for Oto-Rhino-Laryngology Head and Neck Surgery

Proteolytically Active Allergens Cause Barrier Breakdown

(2008) Truus Roelandt et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Shear stress regulates aquaporin-5 and airway epithelial barrier function

(2008) V. K. Sidhaye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA