Article
Fisheries
Michael McGowan, Simon MacKenzie, Nikos Steiropoulos, Manfred Weidmann
Summary: The study tested the efficiency of a qRT-PCR assay for NKA alpha 1a mRNA in assessing seawater readiness of freshwater salmon smolts. The results showed high sensitivity in both lab and mobile assays, with indications of obscured results due to environmental heavy metal contamination.
Article
Oncology
Shutaro Sumiyoshi, Atsushi Shiozaki, Toshiyuki Kosuga, Hiroki Simizu, Michihiro Kudo, Jun Kiuchi, Tomohiro Arita, Hirotaka Konishi, Shuhei Komatsu, Yoshiaki Kuriu, Takeshi Kubota, Hitoshi Fujiwara, Yukiko Morinaga, Eiichi Konishi, Eigo Otsuji
Summary: Na(+)/K+-ATPase & alpha;1 subunit (ATP1A1) exhibits aberrant expression in various types of cancer and its levels in specific tissues are associated with the development of cancer. However, the mechanism and signaling pathways underlying the effects of ATP1A1 in colon cancer (CC) have not been elucidated, and its prognostic impact remains unknown.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Biology
Daphne Z. Hoh, Hsin-Han Lee, Naohisa Wada, Wei-An Liu, Min R. Lu, Cheng-Kuo Lai, Huei-Mien Ke, Pei-Feng Sun, Sen-Lin Tang, Wen-Hsin Chung, Ying-Lien Chen, Chia-Lin Chung, Isheng Jason Tsai
Summary: This study investigates the genome diversity and transcriptome responses of the Fusarium solani species complex (FSSC), which includes fungal pathogens responsible for mortality in animals and plants. The study provides insights into the evolution of FSSC chromosomes and establishes an animal model for fungal pathogens.
Article
Clinical Neurology
Daniel G. Calame, Cristina Moreno Vadillo, Seth Berger, Timothy Lotze, Marwan Shinawi, Javaher Poupak, Corina Heller, Julie Cohen, Richard Person, Aida Telegrafi, Chalongchai Phitsanuwong, Kaylene Fiala, Isabelle Thiffault, Florencia Del Viso, Dihong Zhou, Emily A. Fleming, Tomi Pastinen, Ali Fatemi, Sruthi Thomas, Samuel Pascual, Rosa J. Torres, Carmen Prior, Clara Gomez-Gonzalez, Saskia Biskup, James R. Lupski, Dragan Maric, Miguel Holmgren, Debra Regier, Sho T. Yano
Summary: Calame et al. report that genetic disorders of ATP1A3 can cause spasticity resembling cerebral palsy. They identify a genetic variant that leads to leakage of ions through the sodium-potassium pump and suggest it as a potential rare cause of spastic paraparesis. This study highlights the importance of ATP1A3 in neurological syndromes and provides insight into the molecular basis of phenotypic variability.
Article
Biochemical Research Methods
Ritesh Sharma, Sameer Shrivastava, Sanjay Kumar Singh, Abhinav Kumar, Sonal Saxena, Raj Kumar Singh
Summary: Advancements in genomics have reduced the cost and time of genome sequencing, leading to a vast amount of data in genome databases. The developed model AniAMPpred can identify potential antimicrobial proteins (PAPs) in animal genomes, outperforming other classifiers and providing insights into protein functionality. An online prediction server based on this model is freely accessible for researchers.
BRIEFINGS IN BIOINFORMATICS
(2021)
Article
Agriculture, Multidisciplinary
Jinghua Zhu, Zengxin Li, Meng Zhang, Weiwei Qin, Yoonseong Park, Yueping He
Summary: This study utilized RNA-seq to identify a set of transporter and receptor genes enriched in the excretory organs of the brown planthopper (BPH). RNA interference assays showed that the knockdown of certain genes significantly affected the survival and honeydew secretion of BPH. These genes may serve as potential targets for insect control.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Cell Biology
Wei Chen, Lei Wang, Pengfei Liang, Jason Mast, Clausell Mathis, Catherine Y. Liu, Jin Wei, Jie Zhang, Liying Fu, Luis A. Juncos, Jacentha Buggs, Ruisheng Liu
Summary: This study demonstrates the potential therapeutic effect of using a synchronization modulation electric field to activate Na/K pumps and maintain cellular functions during renal ischemia-reperfusion injury.
SCIENCE TRANSLATIONAL MEDICINE
(2022)
Article
Fisheries
Reem Rida, Razan Zein-Eddine, Sawsan Kreydiyyeh, Antonio Garza de Yta, Imad Patrick Saoud
Summary: This study evaluated the effects of different salinities on the survival, growth, and osmoregulation in redclaw crayfish. The results showed that as salinity increased, the growth rate of redclaw crayfish decreased while sodium potassium ATPase activity and sodium potassium chloride cotransporter expression increased.
JOURNAL OF THE WORLD AQUACULTURE SOCIETY
(2021)
Article
Multidisciplinary Sciences
Noushin Mohammadifard, Faezeh Moazeni, Fatemeh Azizian-Farsani, Mojgan Gharipour, Elham Khosravi, Ladan Sadeghian, Asieh Mansouri, Shahin Shirani, Nizal Sarrafzadegan
Summary: This study examined the effect of genetic variation in salt taste receptors on dietary salt intake and blood pressure in the Iranian population. It found that certain genotypes were associated with higher sodium consumption and diastolic blood pressure. These genetic variations may be related to hypertension and cardiovascular disease risk in this population.
SCIENTIFIC REPORTS
(2023)
Article
Physics, Applied
Kiyotaka Tanaka, Yoshiyuki Kawata, Sang Hyo Kweon, Goon Tan, Takeshi Yoshimura, Isaku Kanno
Summary: Epitaxial growth of lead-free (K,Na)NbO3 (KNN) thin films on (001)SrRuO3/Pt/ZrO2/Si substrates was achieved by using RF magnetron sputtering. The thin films exhibited similar lattice constants and spontaneous polarization as KNN single crystals. Moreover, the thin films had low dielectric constants and relatively high converse piezoelectric coefficients achievable at low voltages.
APPLIED PHYSICS LETTERS
(2022)
Article
Fisheries
Yating Mou, Bing Li, Yiran Hou, Rui Jia, Jian Zhu
Summary: This study investigated the response mechanism of fish to chronic H2O2 exposure and found that it causes incomplete gill structure, decreases potassium concentration while increasing sodium concentration in the plasma, and raises calcium level but decreases potassium and chlorine levels in the gills. Moreover, H2O2 exposure activates the calcium signaling pathway and affects the expression levels of ion-regulation-related genes. Overall, chronic H2O2 exposure alters gill structure, disturbs ion transport, and negatively affects ion equilibrium and osmotic pressure.
Article
Chemistry, Multidisciplinary
Zhi Gao, Aaron Wildenborg, Conrad A. Kocoj, Eric Liu, Caden Sheofsky, Abdelsalam Rawashdeh, Hongwei Qu, Peijun Guo, Jae Yong Suh, Ankun Yang
Summary: Alkali metals have low optical losses but high reactivity, limiting their exploration in optical properties. Sodium has been demonstrated as a low-loss plasmonic material. In this study, we used a thermo-assisted nanoscale embossing technique to fabricate plasmonic nanostructures from pure potassium and NaK liquid alloys. We achieved high-quality-factor resonances in the near-infrared region, expanding the material library for alkali metal plasmonics and liquid plasmonics.
Article
Medicine, Research & Experimental
Elisabeth Petter, Carmen Scheibenbogen, Peter Linz, Christian Stehning, Klaus Wirth, Titus Kuehne, Marcus Kelm
Summary: This study found that muscle sodium content in patients with ME/CFS was higher than in healthy controls before and after exercise. Furthermore, there was an inverse correlation between muscle sodium content and handgrip strength. These findings suggest that sodium overload may play a role in the pathophysiology of ME/CFS and could be a potential therapeutic target.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Medicine, Research & Experimental
George J. Dugbartey
Summary: Hydrogen sulfide (H2S), previously recognized as a toxic gas, has now been acknowledged as an endogenously produced gaseous signaling molecule with diverse physiological and pathological functions at low concentrations. This review focuses on the renal production and functions of H2S, as well as its potential as a targeted therapeutic agent for renal pathologies such as hypertensive nephropathy, diabetic kidney disease, and water balance disorders.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Plant Sciences
Hui Zhang, Qun Hu
Summary: In this study, the TOM1 gene family was found to have a promoting effect on tobacco mosaic virus replication. The TOM1 family originated in the Chlorophyta division and showed a high degree of conservation. These findings not only revealed the conservation of a gene module for promoting virus replication but also provided a valuable strategy for developing TMV-resistant crops.
MOLECULAR PLANT PATHOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Fuqiang Ge, Qiaoling Yu, Jun Zhang, Yaoyao Han, Dongfa Zhu, Xi Xie
Summary: The E93 gene was identified and found to be widely distributed in adult tissues of the swimming crab. The expression levels of PtE93 mRNA in Y-organ and epidermis fluctuated during the molt cycle, suggesting its involvement in juvenile molting. Treatment with 20E induced PtE93 expression, while treatment with MF showed the opposite effect. The study also observed a negative correlation between PtE93 and ecdysteroid biosynthesis genes.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Manuel Marrero, Oscar Monroig, Jose A. Perez, Monica B. Betancor, Ana Galindo, Ana Bolanos, N. Guadalupe Acosta, Covadonga Rodriguez
Summary: This study investigated the combined effects of partial dietary replacement of fish oil (FO) by vegetable oil (VO) and reduced ambient salinity on the fatty acid composition of C. labrosus juveniles. The results showed that C. labrosus is able to biosynthesise EPA and DHA from ALA, and low salinity conditions can upregulate the gene expression related to fatty acid metabolism. Fish reared on FO20 diet showed the highest amount of n-3 LC-PUFA in muscle.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Davide Degli Esposti, Aureline Lalouette, Karen Gaget, Louveline Lepeule, Zineb Chaabi, Maxime Lepretre, Anabelle Espeyte, Nicolas Delorme, Herve Queau, Laura Garnero, Federica Calevro, Arnaud Chaumot, Olivier Geffard
Summary: Metal pollution has significant effects on aquatic environments, and metallothioneins play important roles in maintaining metal homeostasis and detoxification. This study identified two metallothionein-coding transcripts in Gammarus fossarum and investigated their organ-specific expression patterns. The results showed that mt1 was more strongly induced after cadmium exposure, and mt1 was more highly induced in the caeca compared to the gills for any metal exposure. Additionally, mt2 was more inducible in the gills than in the caeca for cadmium and zinc exposure at the individual level.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Cuihong You, Shuangshuang Miao, Zhiyong Xie, Siyuan Lin, Shuqi Wang, Cuiying Chen, Li Lin, Yanhua Huang, Meng Zhou, Yewei Dong, Yuanyou Li, Ping Zhuang
Summary: The rabbitfish S. guttatus was found to have the capability for LC-PUFA biosynthesis, with the expression of related genes varying temporally and spatially during embryogenesis and being influenced by ambient salinity.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Saydur Rahman, Mohammad Maruf Billah, Victor Rangel, Esmirna Cantu
Summary: Global warming has severe impacts on the reproductive fitness of marine invertebrates. In this study, the researchers used various techniques to investigate the effects of high temperatures on global DNA methylation, cellular apoptosis, and nitrative stress in the gonads of Atlantic sea urchins.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
E. S. Kladchenko, A. A. Tkachuk, M. S. Podolskaya, A. Yu. Andreyeva
Summary: This study investigated the osmotic stability and cellular responses of hemocytes in Mediterranean mussel and Pacific oyster. The results revealed that both species showed cellular volume changes and alterations in mitochondrial membrane potential upon hypoosmotic swelling. These findings provide insights into the cellular responses of bivalve mollusks to osmotic stress.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Yuya Ohhara, Chiemi Sagisaka, Kimiko Yamakawa-Kobayashi
Summary: This study investigated the biosynthetic capacity of n-3 PUFAs in the terrestrial invertebrate Sinella dubiosa, and found that it can metabolize oleic, linolenic, and arachidonic acids to produce EPA, suggesting that it may serve as an EPA source in soil ecosystems.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Correction
Biochemistry & Molecular Biology
N. Perales-Garcia, D. Tovar-Ramirez, M. G. Martinez-Morales, B. P. Ceballos-Vazquez, D. A. Corona-Rojas, M. A. Salcedo-Meza, A. Garrido-Mora, F. Vega-Villasante, H. Nolasco-Soria
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
N. Perales-Garcia, D. Tovar-Ramirez, M. G. Martinez-Morales, B. P. Ceballos-Vazquez, D. A. Corona-Rojas, M. A. Salcedo-Meza, A. Garrido-Mora, F. Vega-Villasante, H. Nolasco-Soria
Summary: This study provides the first report on the digestive tract pH of the pygmy octopus. The pH of the digestive tract regions was found to be lower than 7.0 and did not differ significantly between wild and captive octopuses. The digestive gland had the lowest pH values, but they were still above 5.0.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Carlos Espirito-Santo, Carmen Alburquerque, Francisco A. Guardiola, Rodrigo O. A. Ozorio, Leonardo J. Magnoni
Summary: Swimming has physiological effects on farmed fish, but the potential link between swimming and oxidative stress is still poorly understood. This study investigated the impact of different moderate swimming conditions on the antioxidant status of gilthead seabream, revealing that swimming modulated the activity of antioxidant enzymes in the liver and skeletal muscle. Adequate swimming conditions were found to minimize oxidative stress in gilthead seabream.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Yingxin Zhang, Chaobin Qin, Junli Wang, Liping Yang, Xiao Yan, Shaoyang Zhi, Guoxing Nie
Summary: The study focuses on the expression patterns of PFK genes in response to glucose, insulin, and glucagon stimuli in grass carp. The findings suggest that PFK family genes have different or even opposite expression patterns in various tissues, which may contribute to glucose intolerance in fish.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jianshuang Li, Likang Lyu, Haishen Wen, Yun Li, Xiaojie Wang, Yijia Yao, Xin Qi
Summary: This study investigated the transcriptional regulation of estrogen receptors (ESRs) on isotocin receptors (itrs) in guppies, and found that estrogen can regulate oxytocin receptor expression in ovoviviparous teleosts. The study also demonstrated that ESR1 represses itr2 promoter activity in an estrogen-dependent manner, while overexpression of ESR2a or ESR2b enhances itr2 promoter activity.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Wan-Xin Li, Li-Ting Cai, Yan-Ping Huang, Yuan-Qing Huang, Shu-Hui Pan, Zhi-Long Liu, Charles Brighton Ndandala, Gang Shi, Si-Ping Deng, Hong-Juan Shi, Guang-Li Li, Dong-Neng Jiang
Summary: In this study, it was found that S. argus has two lep genes, with lepa highly expressed in the liver and lepb not detected in any tissue. lepa was found to play a role in regulating female reproduction in S. argus.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Li-Xiang Wu, Xiao-Ying Tan, Yi-Chuang Xu, Hua Zheng, Xiao-Lei Wei, Wu-Hong Lv, Zhi Luo
Summary: This study investigates the mechanisms underlying the activation of lipophagy in yellow catfish under high glucose-induced lipid deposition. The SIRT1-NRF2-TFEB pathway is proposed to mediate lipophagy activation, and lipophagy helps alleviate high glucose-induced lipid deposition. This study provides insights into the control of lipophagy in response to metabolic stress.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2024)