Loss of miR-101-3p Promotes Transmigration of Metastatic Breast Cancer Cells through the Brain Endothelium by Inducing COX-2/MMP1 Signaling

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MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

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Clinical Value of miR-101-3p and Biological Analysis of its Prospective Targets in Breast Cancer: A Study Based on The Cancer Genome Atlas (TCGA) and Bioinformatics

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Vascular mimicry formation is promoted by paracrine TGF-β and SDF1 of cancer-associated fibroblasts and inhibited by miR-101 in hepatocellular carcinoma

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miR-101 inhibits glioma cell invasion via the downregulation of COX-2

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Emerging Strategies for Treating Brain Metastases from Breast Cancer

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Roles of the Cyclooxygenase 2 Matrix Metalloproteinase 1 Pathway in Brain Metastasis of Breast Cancer

(2015) Kerui Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-122 – A key factor and therapeutic target in liver disease

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miR-509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF-α

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The Blood–Brain Barrier

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Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier

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Hsa-microRNA-181a is a regulator of a number of cancer genes and a biomarker for endometrial carcinoma in patients: a bioinformatic and clinical study and the therapeutic implication

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MiRNA-101 inhibits breast cancer growth and metastasis by targeting CX chemokine receptor 7

(2015) Jun-Tang Li et al.   Oncotarget

Cyclooxygenase-2, a Potential Therapeutic Target, Is Regulated by miR-101 in Esophageal Squamous Cell Carcinoma

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miR-101 Promotes Breast Cancer Cell Apoptosis by Targeting Janus Kinase 2

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MicroRNAs in Brain Metastases: Potential Role as Diagnostics and Therapeutics

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STRING v10: protein–protein interaction networks, integrated over the tree of life

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Role of the Blood-Brain Barrier in the Formation of Brain Metastases

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HIV-1 Tat C Modulates Expression of miRNA-101 to Suppress VE-Cadherin in Human Brain Microvascular Endothelial Cells

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The role of claudin-5 in blood-brain barrier (BBB) and brain metastases (Review)

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First microRNA mimic enters clinic

(2013) Aaron Bouchie   NATURE BIOTECHNOLOGY

Antitumor activity of the selective cyclooxygenase-2 inhibitor, celecoxib, on breast cancer in Vitro and in Vivo

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Downregulation of miR-101 in gastric cancer correlates with cyclooxygenase-2 overexpression and tumor growth

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MiR-101 Is Involved in Human Breast Carcinogenesis by Targeting Stathmin1

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Enforced Expression of miR-101 Inhibits Prostate Cancer Cell Growth by Modulating the COX-2 PathwayIn Vivo

(2011) Yubin Hao et al.   Cancer Prevention Research

MicroRNA-1258 Suppresses Breast Cancer Brain Metastasis by Targeting Heparanase

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A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

(2011) Kim J. Png et al.   NATURE

The biology of brain metastases—translation to new therapies

(2011) April F. Eichler et al.   Nature Reviews Clinical Oncology

MicroRNA-mediated breast cancer metastasis: from primary site to distant organs

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Genes that mediate breast cancer metastasis to the brain

(2009) Paula D. Bos et al.   NATURE

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

MiR-101 downregulation is involved in cyclooxygenase-2 overexpression in human colon cancer cells

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Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

MicroRNAs accurately identify cancer tissue origin

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