Lipoxygenase Inhibition Activity of Coumarin Derivatives—QSAR and Molecular Docking Study

An extensive study of coumarin synthesis via Knoevenagel condensation in choline chloride based deep eutectic solvents

(2020) Melita Lončarić et al.   CURRENT ORGANIC SYNTHESIS

Recent Advances in the Synthesis of Coumarin Derivatives from Different Starting Materials

(2020) Melita Lončarić et al.   Biomolecules

Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential

(2019) Ola S. Afifi et al.   BIOORGANIC CHEMISTRY

Potential of faba bean lipase and lipoxygenase to promote formation of volatile lipid oxidation products in food models

(2019) Anna-Maija Lampi et al.   FOOD CHEMISTRY

Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX

(2018) Aikaterini Peperidou et al.   MOLECULES

Application of Docking Analysis in the Prediction and Biological Evaluation of the Lipoxygenase Inhibitory Action of Thiazolyl Derivatives of Mycophenolic Acid

(2018) Evangelia Tsolaki et al.   MOLECULES

Environmentally Friendly Approach to Knoevenagel Condensation of Rhodanine in Choline Chloride: Urea Deep Eutectic Solvent and QSAR Studies on Their Antioxidant Activity

(2018) Maja Molnar et al.   MOLECULES

O-prenylated 3-carboxycoumarins as a novel class of 15-LOX-1 inhibitors

(2017) Atena Jabbari et al.   PLoS One

Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives

(2016) Pavan Srivastava et al.   BIOORGANIC CHEMISTRY

Synthesis and evaluation of novel quinazolinone-1,2,3-triazoles as inhibitors of lipoxygenase

(2016) Fatemeh Farjadmand et al.   JOURNAL OF CHEMICAL RESEARCH

Recent progress in the drug development of coumarin derivatives as potent antituberculosis agents

(2015) Rangappa S. Keri et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 5-benzylidenerhodanine-3-acetic acid derivatives as AChE and 15-LOX inhibitors

(2015) Negah Shafii et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Oxylipins in the spikemoss Selaginella martensii: Detection of divinyl ethers, 12-oxophytodienoic acid and related cyclopentenones

(2015) Anna V. Ogorodnikova et al.   PHYTOCHEMISTRY

The structural basis for specificity in lipoxygenase catalysis

(2015) Marcia E. Newcomer et al.   PROTEIN SCIENCE

Synthesis and Evaluation of Coumarin–Resveratrol Hybrids as 15-Lipoxygenaze Inhibitors

(2015) Samira Rahmani-Nezhad et al.   SYNTHETIC COMMUNICATIONS

Structural modifications of coumarin derivatives: Determination of antioxidant and lipoxygenase (LOX) inhibitory activity

(2014) Marina Roussaki et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Effect of information leakage and method of splitting (rational and random) on external predictive ability and behavior of different statistical parameters of QSAR model

(2014) Vijay H. Masand et al.   MEDICINAL CHEMISTRY RESEARCH

Stress-dependent regulation of 13-lipoxygenases and 13-hydroperoxide lyase in olive fruit mesocarp

(2014) María N. Padilla et al.   PHYTOCHEMISTRY

Effects of recombinant lipoxygenase on wheat flour, dough and bread properties

(2013) Chong Zhang et al.   FOOD RESEARCH INTERNATIONAL

QSARINS: A new software for the development, analysis, and validation of QSAR MLR models

(2013) Paola Gramatica et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Identification of lipoxygenase (LOX) genes putatively involved in fruit flavour formation in apple (Malus × domestica)

(2013) Jörg Vogt et al.   Tree Genetics & Genomes

Conversion of human 5-lipoxygenase to a 15-lipoxygenase by a point mutation to mimic phosphorylation at Serine-663

(2012) Nathaniel C. Gilbert et al.   FASEB JOURNAL

On the Use of the Metric rm 2 as an Effective Tool for Validation of QSAR Models in Computational Drug Design and Predictive Toxicology

(2012) K. Roy et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Extraction, Isolation And Characterization Of Bioactive Compounds From Plants’ Extracts

(2011) S Sasidharan et al.   African Journal of Traditional Complementary and Alternative Medicines

A review on coumarins as acetylcholinesterase inhibitors for Alzheimer’s disease

(2011) Preet Anand et al.   BIOORGANIC & MEDICINAL CHEMISTRY

iGEMDOCK: a graphical environment of enhancing GEMDOCK using pharmacological interactions and post-screening analysis

(2011) Kai-Cheng Hsu et al.   BMC BIOINFORMATICS

Molecular enzymology of lipoxygenases

(2010) Igor Ivanov et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A novel synthesis of 3-aryl coumarins and evaluation of their antioxidant and lipoxygenase inhibitory activity

(2010) Marina Roussaki et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Cationic substrates of soybean lipoxygenase-1

(2010) Lucas E. Chohany et al.   BIOORGANIC CHEMISTRY

Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors

(2009) Theodoros Symeonidis et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts

(2009) Georgia Melagraki et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Kukoamine A analogs with lipoxygenase inhibitory activity

(2009) Dimitra Hadjipavlou-Litina et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Antioxidant activities of coumarins from Korean medicinal plants and their structure–activity relationships

(2009) Phuong Thien Thuong et al.   PHYTOTHERAPY RESEARCH

Radical scavenging capacities of some thiazolylthiazolidine-2,4-dione derivatives

(2008) Oya Bozdağ-Dündar et al.   MEDICINAL CHEMISTRY RESEARCH