Apohemoglobin-haptoglobin complexes attenuate the hypertensive response to low-molecular-weight polymerized hemoglobin

Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme

(2020) Carlos J. Munoz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Prepare to adapt: blood supply and transfusion support during the first 2 weeks of the 2019 novel coronavirus ( COVID ‐19) pandemic affecting Washington State

(2020) Monica B. Pagano et al.   TRANSFUSION

Adenosine‐induced transient hypotension for carotid artery injury during endoscopic skull‐base surgery: case report and review of the literature

(2019) Judd H. Fastenberg et al.   International Forum of Allergy & Rhinology

Novel manufacturing method for producing apohemoglobin and its biophysical properties

(2019) Ivan S. Pires et al.   BIOTECHNOLOGY AND BIOENGINEERING

Controlled Polymerization and Ultrafiltration Increase the Consistency of Polymerized Hemoglobin for Use as an Oxygen Carrier

(2019) Donald A. Belcher et al.   BIOCONJUGATE CHEMISTRY

Comprehensive Biochemical and Biophysical Characterization of Hemoglobin-Based Oxygen Carrier Therapeutics: All HBOCs Are Not Created Equally

(2018) Fantao Meng et al.   BIOCONJUGATE CHEMISTRY

The quaternary state of polymerized human hemoglobin regulates oxygenation of breast cancer solid tumors: A theoretical and experimental study

(2018) Donald A. Belcher et al.   PLoS One

Molecular Size Modulates Pharmacokinetics, Biodistribution, and Renal Deposition of the Drug Delivery Biopolymer Elastin-like Polypeptide

(2018) Marija Kuna et al.   Scientific Reports

Normalization of hemoglobin-based oxygen carrier-201 induced vasoconstriction: targeting nitric oxide and endothelin

(2017) Yannick J. Taverne et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mechanisms of Toxicity and Modulation of Hemoglobin-Based Oxygen Carriers (HBOCs)

(2017) Abdu I. Alayash   SHOCK

An Inter-regional US Blood Supply Simulation Model to Evaluate Blood Availability to Support Planning for Emergency Preparedness and Medical Countermeasures

(2017) Arianna Simonetti et al.   Disaster Medicine and Public Health Preparedness

Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation

(2017) Donald Andrew Belcher et al.   PLoS One

Haptoglobin Preserves Vascular Nitric Oxide Signaling during Hemolysis

(2016) Christian A. Schaer et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Blood Substitutes

(2014) Andre F. Palmer et al.   Annual Review of Biomedical Engineering

Effects of a hemoglobin-based oxygen carrier (HBOC-201) and derivatives with altered oxygen affinity and viscosity on systemic and microcirculatory variables in a top-load rat model

(2014) Bjorn Kyungsuck Song et al.   MICROVASCULAR RESEARCH

Haptoglobin, hemopexin, and related defense pathways—basic science, clinical perspectives, and drug development

(2014) Dominik J. Schaer et al.   Frontiers in Physiology

Resuscitation from hemorrhagic shock using polymerized hemoglobin compared to blood

(2013) Daniel Ortiz et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Haptoglobin Preferentially Binds β but Not α Subunits Cross-Linked Hemoglobin Tetramers with Minimal Effects on Ligand and Redox Reactions

(2013) Yiping Jia et al.   PLoS One

Encapsulation of hemoglobin inside liposomes surface conjugated with poly(ethylene glycol) attenuates their reactions with gaseous ligands and regulates nitric oxide dependent vasodilation

(2012) Shahid Rameez et al.   BIOTECHNOLOGY PROGRESS

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

(2012) D. J. Schaer et al.   BLOOD

Reactivity of Polymersome Encapsulated Hemoglobin with Physiologically Important Gaseous Ligands: Oxygen, Carbon Monoxide, and Nitric Oxide

(2012) Shahid Rameez et al.   MACROMOLECULES

Down Selection of Polymerized Bovine Hemoglobins for Use as Oxygen Releasing Therapeutics in a Guinea Pig Model

(2012) Jin Hyen Baek et al.   TOXICOLOGICAL SCIENCES

Simple Method for Preparing Poly(ethylene glycol)-Surface-Conjugated Liposome-Encapsulated Hemoglobins: Physicochemical Properties, Long-Term Storage Stability, and Their Reactions with O2, CO, and NO

(2011) Shahid Rameez et al.   LANGMUIR

Hemoglobin-based Oxygen Carriers: First, Second or Third Generation? Human or Bovine? Where are we Now?

(2009) Lena M. Napolitano   CRITICAL CARE CLINICS

Effects of the molecular mass of tense-state polymerized bovine hemoglobin on blood pressure and vasoconstriction

(2009) Pedro Cabrales et al.   JOURNAL OF APPLIED PHYSIOLOGY

HBOC-201 Vasoactivity in a Phase III Clinical Trial in Orthopedic Surgery Subjects—Extrapolation of Potential Risk for Acute Trauma Trials

(2009) Daniel Freilich et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Prevention of the Pulmonary Vasoconstrictor Effects of HBOC-201 in Awake Lambs by Continuously Breathing Nitric Oxide

(2008) Binglan Yu et al.   ANESTHESIOLOGY

Tangential flow filtration of hemoglobin

(2008) Andre F. Palmer et al.   BIOTECHNOLOGY PROGRESS