Targeting NF-κB Signaling by Calebin A, a Compound of Turmeric, in Multicellular Tumor Microenvironment: Potential Role of Apoptosis Induction in CRC Cells

Colorectal cancer statistics, 2020

(2020) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Carcinogenesis of Pancreatic Ductal Adenocarcinoma

(2020) Peter Storz et al.   GASTROENTEROLOGY

Calebin A Potentiates the Effect of 5-FU and TNF-β (Lymphotoxin α) against Human Colorectal Cancer Cells: Potential Role of NF-κB

(2020) Constanze Buhrmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Evidence that TNF-β induces proliferation in colorectal cancer cells and resveratrol can down-modulate it

(2019) Constanze Buhrmann et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Calebin-A induced death of malignant peripheral nerve sheath tumor cells by activation of histone acetyltransferase

(2019) Ming-Jen Lee et al.   PHYTOMEDICINE

Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol

(2019) Constanze Buhrmann et al.   Nutrients

Targeting Tumor Microenvironment for Cancer Therapy

(2019) Catarina Roma-Rodrigues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Lymphotoxin-α promotes tumor angiogenesis in HNSCC by modulating glycolysis in a PFKFB3-dependent manner

(2019) Jie-Gang Yang et al.   INTERNATIONAL JOURNAL OF CANCER

Natural products for treating colorectal cancer: A mechanistic review

(2019) Xuan-mei Huang et al.   BIOMEDICINE & PHARMACOTHERAPY

Colorectal cancer

(2019) Evelien Dekker et al.   LANCET

Evidence That Calebin A, a Component of Curcuma Longa Suppresses NF-κB Mediated Proliferation, Invasion and Metastasis of Human Colorectal Cancer Induced by TNF-β (Lymphotoxin)

(2019) Constanze Buhrmann et al.   Nutrients

Role of the NF-κB signaling pathway in the pathogenesis of colorectal cancer

(2019) Atena Soleimani et al.   GENE

Role of the NFκB-signaling pathway in cancer

(2018) Longzheng Xia et al.   OncoTargets and Therapy

Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells

(2018) Constanze Buhrmann et al.   Nutrients

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Biophysics of Tumor Microenvironment and Cancer Metastasis - A Mini Review

(2018) Bashar Emon et al.   Computational and Structural Biotechnology Journal

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Calebin A, a novel component of turmeric, suppresses NF-κB regulated cell survival and inflammatory gene products leading to inhibition of cell growth and chemosensitization

(2017) Amit K. Tyagi et al.   PHYTOMEDICINE

Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α

(2017) Constanze Buhrmann et al.   PLoS One

Phytomedicine—Modulating oxidative stress and the tumor microenvironment for cancer therapy

(2016) Yu-Ting Cheng et al.   PHARMACOLOGICAL RESEARCH

Roles of NF-κB in Cancer and Inflammatory Diseases and Their Therapeutic Approaches

(2016) Mi Park et al.   Cells

Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer

(2015) Mehdi Shakibaei et al.   BMC CANCER

Cancer prevention and therapy through the modulation of the tumor microenvironment

(2015) Stephanie C. Casey et al.   SEMINARS IN CANCER BIOLOGY

Colorectal cancer

(2015) Ernst J. Kuipers et al.   Nature Reviews Disease Primers

Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric

(2013) Bharat B. Aggarwal et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration

(2012) Valbona Luga et al.   CELL

Multitargeting by turmeric, the golden spice: From kitchen to clinic

(2012) Subash C. Gupta et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Turmeric (Curcuma longa) inhibits inflammatory nuclear factor (NF)-κB and NF-κB-regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis

(2011) Ji H. Kim et al.   MOLECULAR NUTRITION & FOOD RESEARCH

TNF-α-Induced Mitochondrial Alterations in Human T Cells Requires FADD and Caspase-8 Activation but Not RIP and Caspase-3 Activation

(2010) Mehdi Shakibaei et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of NF-κB Signaling by Quinacrine Is Cytotoxic to Human Colon Carcinoma Cell Lines and Is Synergistic in Combination with Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) or Oxaliplatin

(2010) Tanvi S. Jani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammation and cancer: how friendly is the relationship for cancer patients?

(2009) Bharat B Aggarwal et al.   CURRENT OPINION IN PHARMACOLOGY

Calebin-A induces apoptosis and modulates MAPK family activity in drug resistant human gastric cancer cells

(2008) Yan Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TNF: A master switch for inflammation to cancer

(2008) Gautam Sethi   Frontiers in Bioscience-Landmark

Targeting Nuclear Factor- B Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis

(2008) G. Sethi et al.   MOLECULAR CANCER RESEARCH

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE