Common biochemical properties of metabolic genes recurrently dysregulated in tumors

Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers

(2018) Xinxin Peng et al.   Cell Reports

A Landscape of Metabolic Variation across Tumor Types

(2018) Ed Reznik et al.   Cell Systems

Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas

(2018) S. R. Rosario et al.   Nature Communications

Genome scale metabolic modeling of cancer

(2017) Avlant Nilsson et al.   METABOLIC ENGINEERING

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

(2017) Jiyeon Kim et al.   NATURE

Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

(2017) Grant M. Fischer et al.   Pigment Cell & Melanoma Research

Serine and Functional Metabolites in Cancer

(2017) Alice C. Newman et al.   TRENDS IN CELL BIOLOGY

Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling

(2017) Sriram Chandrasekaran et al.   Cell Reports

Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition

(2017) Keisha N. Hardeman et al.   Scientific Reports

Integrated analysis of gene expression and copy number identified potential cancer driver genes with amplification-dependent overexpression in 1,454 solid tumors

(2017) Keiichi Ohshima et al.   Scientific Reports

The Emerging Hallmarks of Cancer Metabolism

(2016) Natalya N. Pavlova et al.   Cell Metabolism

Metabolic rewiring in melanoma

(2016) B I Ratnikov et al.   ONCOGENE

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

Modeling cancer metabolism on a genome scale

(2015) K. Yizhak et al.   Molecular Systems Biology

Molecular drivers of cellular metabolic reprogramming in melanoma

(2015) Cecilie Abildgaard et al.   TRENDS IN MOLECULAR MEDICINE

Prognostic and therapeutic significance of ribonucleotide reductase small subunit M2 in estrogen-negative breast cancers

(2014) Hang Zhang et al.   BMC CANCER

Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling

(2014) R. Agren et al.   Molecular Systems Biology

Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer

(2014) Roland Nilsson et al.   Nature Communications

Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer

(2014) Keren Yizhak et al.   eLife

Pathway-Centric Integrative Analysis Identifies RRM2 as a Prognostic Marker in Breast Cancer Associated with Poor Survival and Tamoxifen Resistance

(2014) Nagireddy Putluri et al.   NEOPLASIA

Heterogeneity of tumor-induced gene expression changes in the human metabolic network

(2013) Jie Hu et al.   NATURE BIOTECHNOLOGY

Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

(2012) Patrick S. Ward et al.   CANCER CELL

Glucose transporters in cancer metabolism

(2012) Kehinde Adekola et al.   CURRENT OPINION IN ONCOLOGY

How cancer metabolism is tuned for proliferation and vulnerable to disruption

(2012) Almut Schulze et al.   NATURE

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

(2011) Jason W Locasale et al.   NATURE GENETICS

Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

SABIO-RK--database for biochemical reaction kinetics

(2011) U. Wittig et al.   NUCLEIC ACIDS RESEARCH

Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models

(2010) Nathan E Lewis et al.   Molecular Systems Biology

PrognoScan: a new database for meta-analysis of the prognostic value of genes

(2009) Hideaki Mizuno et al.   BMC Medical Genomics

Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity

(2009) T. D. Pfister et al.   MOLECULAR CANCER THERAPEUTICS

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Network-based prediction of human tissue-specific metabolism

(2008) Tomer Shlomi et al.   NATURE BIOTECHNOLOGY